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Isoforms Recommended:	ErbB3/HER3

Results for "

ERBB3/HER3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) EGFR (7) ERK (2) PARP (1) PROTACs (1) Survivin (1)
By Research Areas:	Cancer (6)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99866

Duligotuzumab MEHD-7945A; RG 7597	EGFR	Others
Duligotuzumab (MEHD-7945A; RG 7597) is a humanized IgG-κ monoclonal antibody that specifically targets Her3 (ErbB3) .

HY-P99304

Lumretuzumab Anti-Human ERBB3 Recombinant Antibody	EGFR	Cancer
Lumretuzumab (Anti-Human ERBB3 Recombinant Antibody) is a humanized anti-HER3 *(ERBB3)* monoclonal antibody that can be used for the research of cancer .

HY-100848

TX1-85-1 1 Publications Verification	EGFR	Cancer
TX1-85-1 is an irreversible **Her3 (ErbB3) inhibitor with an IC₅₀** of 23 nM. TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling .

HY-P99275

Patritumab 1 Publications Verification Human Anti-ERBB3 Recombinant Antibody	EGFR Akt ERK PARP Survivin	Cancer
Patritumab (Human Anti-ERBB3 Recombinant Antibody) is a neutralizing monoclonal antibody to *ERBB3. Patritumab shows a synergy with Cetuximab (HY-P9905), potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis* and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors .

HY-P991245

*Anti-ERBB3/HER3* (SGP1)**	EGFR	Cancer
Anti-ERBB3/HER3 (SGP1) is a human monoclonal antibody (mAb) targeting *ERBB3/HER3. Anti-ERBB3/HER3* (SGP1) inhibits Neuregulin stimulated growth of cultured breast cancer cells. Anti-ERBB3/HER3 (SGP1) can be used in breast cancer research .

HY-P991241

*Anti-ERBB3/HER3* (29Z6)**	EGFR	Cancer
Anti-ERBB3/HER3 (29Z6) is an antibody inhibitor, targeting to human ERBB3/HER3.

HY-118998

TX2-121-1	PROTACs EGFR ERK Akt	Cancer
TX2-121-1 is a potent and selective **Her3 (ErbB3) degrader that contains a hydrophobic adamantane moiety. TX2-121-1 has an IC₅₀** of 49 nM for Her3. TX2-121-1 inhibits Her3-dependent signaling and heterodimerization of Her3. TX2-121-1 has the ability to inhibit cell proliferation. TX2-121-1 can be used in the study of tumors. (Pink: Her3 inhibitor (HY-164988); Black: Linker; Blue: Adamantane (HY-N2427)) .

Cat. No.	Product Name	Target	Research Area

HY-P99866

Duligotuzumab MEHD-7945A; RG 7597	EGFR	Others
Duligotuzumab (MEHD-7945A; RG 7597) is a humanized IgG-κ monoclonal antibody that specifically targets Her3 (ErbB3) .

HY-P99304

Lumretuzumab Anti-Human ERBB3 Recombinant Antibody	EGFR	Cancer
Lumretuzumab (Anti-Human ERBB3 Recombinant Antibody) is a humanized anti-HER3 *(ERBB3)* monoclonal antibody that can be used for the research of cancer .

HY-P99275

Patritumab 1 Publications Verification Human Anti-ERBB3 Recombinant Antibody	EGFR Akt ERK PARP Survivin	Cancer
Patritumab (Human Anti-ERBB3 Recombinant Antibody) is a neutralizing monoclonal antibody to *ERBB3. Patritumab shows a synergy with Cetuximab (HY-P9905), potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis* and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors .

HY-P991245

*Anti-ERBB3/HER3* (SGP1)**	EGFR	Cancer
Anti-ERBB3/HER3 (SGP1) is a human monoclonal antibody (mAb) targeting *ERBB3/HER3. Anti-ERBB3/HER3* (SGP1) inhibits Neuregulin stimulated growth of cultured breast cancer cells. Anti-ERBB3/HER3 (SGP1) can be used in breast cancer research .

HY-P991241

*Anti-ERBB3/HER3* (29Z6)**	EGFR	Cancer
Anti-ERBB3/HER3 (29Z6) is an antibody inhibitor, targeting to human ERBB3/HER3.

Recombinant Proteins Recommended:

ErbB3/HER3

Species:	Human (10) Rhesus Macaque (3) Rat (2) Mouse (1)
Tag:	His (10) Tag Free (1) Avi (3) GST (1) Fc (5)
Source:	HEK293 (15) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P72625

	HER3 Protein, Human (HEK293, His) Receptor tyrosine-protein kinase ERBB-3; ERBB3; HER3	Human	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Human (HEK293, His) is the recombinant human-derived HER3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P74891

	HER3 Protein, Rat (HEK293, His) Receptor tyrosine-protein kinase ERBB-3; ERBB3; HER3	Rat	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Rat (HEK293, His) is the recombinant rat-derived HER3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76968

	HER3 Protein, Rhesus Macaque (HEK293, Fc) Receptor tyrosine-protein kinase ERBB-3; ERBB3; HER3	Rhesus Macaque	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived HER3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72625A

	HER3 Protein, Human (HEK293, His, solution) Receptor tyrosine-protein kinase ERBB-3; ERBB3; HER3	Human	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Human (HEK293, His, solution) is the recombinant human-derived HER3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P74892

	HER3 Protein, Rat (HEK293, Fc) Receptor tyrosine-protein kinase ERBB-3; ERBB3; HER3	Rat	HEK293
	HER3 is a tyrosine-protein kinase that is a key cell surface receptor for neuregulin. ErbB2 and ErbB3 can form dimers and activate signaling pathways including MAPK, PI3K/Akt and PLC纬 to promote tumor development. HER3 Protein, Rat (HEK293, Fc) is the recombinant rat-derived HER3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76967

	HER3 Protein, Rhesus Macaque (HEK293) Receptor tyrosine-protein kinase ERBB-3; ERBB3; HER3	Rhesus Macaque	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Rhesus Macaque (HEK293) is the recombinant Rhesus Macaque-derived HER3 protein, expressed by HEK293 , with tag free.

HY-P74893

	HER3 Protein, Human (sf9, His-GST) Receptor tyrosine-protein kinase ERBB-3; ERBB3; HER3	Human	Sf9 insect cells
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Human (sf9, His-GST) is the recombinant human-derived HER3 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P76969

	HER3 Protein, Rhesus Macaque (HEK293, His) Receptor tyrosine-protein kinase ERBB-3; ERBB3; HER3	Rhesus Macaque	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived HER3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77554

	HER3 Protein, Human (Biotinylated, HEK293, His) Receptor tyrosine-protein kinase ERBB-3; ERBB3; HER3	Human	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived HER3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P70857

	HER3 Protein, Mouse (HEK293, His) Proto-oncogene-like protein c-ERBB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3	Mouse	HEK293
	HER3 Protein, a vital tyrosine-protein kinase and neuregulin cell surface receptor, activates upon binding to neuregulin-1 (NRG1), enhancing phosphorylation on tyrosine residues and associating with the p85 subunit of phosphatidylinositol 3-kinase. It is also activated by CSPG5 and plays a crucial role in regulating myeloid cell differentiation. HER3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived HER3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P78452

	HER3 Protein, Human (HEK293, His-Avi) ERBB3; ERBB-3; HER3; HER3c-ERBB-3; LCCS2; MDA-BF-1; MGC88033; p180-ERBB3; p45-sERBB3; p85-sERBB3; ERBB3	Human	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Human (HEK293, His-Avi) is the recombinant human-derived HER3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P70322

	HER3 Protein, Human (HEK293, Fc) rHuReceptor tyrosine-protein kinase ERBB-3/HER3, Fc; Proto-oncogene-like protein c-ERBB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3	Human	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Human (HEK293, Fc) is the recombinant human-derived HER3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P704661

	HER3 Protein, Human (HEK293, mFc) rHuReceptor tyrosine-protein kinase ERBB-3/HER3, Fc; Proto-oncogene-like protein c-ERBB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3	Human	HEK293

HY-P72375

	HER3 Protein, Human (Biotinylated, HEK293, His-Avi) Proto-oncogene-like protein c-ERBB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3	Human	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived HER3 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.

HY-P70323

	HER3 Protein, Human (312a.a, HEK293, Fc) rHuReceptor tyrosine-protein kinase ERBB-3/HER3-312AA, Fc; Proto-oncogene-like protein c-ERBB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3	Human	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Human (312a.a, HEK293, Fc) is the recombinant human-derived HER3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P701281

	FITC-labeled HER3 Protein, Human (HEK293, His-Avi) ERBB3; HER3; LCCS2; MDA-BF-1; MGC88033; c-ERBB3; ERBB3-S; p180-ERBB3; p45-sERBB3; p85-sERBB3	Human	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. FITC-labeled HER3 Protein, Human (HEK293, His) is the recombinant human-derived FITC-labeled HER3 protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

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HY-P84183

	ERBB3 Antibody (YA3880) HER3; c-ERBB3	WB, ICC/IF, ELISA	Human

HY-P80659

	ErbB 3 Antibody (YA457) ERBB3; HER3; Receptor tyrosine-protein kinase ERBB-3; Proto-oncogene-like protein c-ERBB-3; Tyrosine kinase-type cell surface receptor HER3	WB	Human
	ErbB 3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 148 kDa, targeting to ErbB 3. It can be used for WB assays with tag free, in the background of Human.

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