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E.coli metabolite

" in MedChemExpress (MCE) Product Catalog:

18

Inhibitors & Agonists

1

Peptides

14

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-133154
    Carboxyaminoimidazole ribotide
    2 Publications Verification

    CAIR; 4-Carboxy-AIR

    		 Endogenous Metabolite Infection
    Carboxyaminoimidazole ribotide (CAIR) is a metabolite of E. coli. Carboxyaminoimidazole ribotide can be used to detect distinctive features of E. coli PurE active site and synthesis fungal de novo purine .
    Carboxyaminoimidazole ribotide
  • HY-113247
    trans-trans-Muconic acid

    		Endogenous Metabolite Metabolic Disease
    trans-trans-Muconic acid is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in human. trans-trans-Muconic acid is mutagenic in an E. coli assay .
    trans-trans-Muconic acid
  • HY-141465
    3-Hydroxybutyryl-CoA

    		Endogenous Metabolite Metabolic Disease
    3-Hydroxybutyryl-CoA is a metabolite which can be found in mouse or E.coli, et al. 3-Hydroxybutyryl-CoA has a 3-hydroxybutanoyl as the S-acyl component, and is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan .
    3-Hydroxybutyryl-CoA
  • HY-E70248
    S-(3-Hydroxydodecanoate)-CoA

    		Endogenous Metabolite Others
    S-(3-Hydroxydodecanoate)-CoACoenzyme A, a Coenzyme A, is a metabolite that can be found or produced in E. coli (strain K12, MG1655) .
    S-(3-Hydroxydodecanoate)-CoA
  • HY-154871
    α-D-Glucosamine 1-phosphate

    		Endogenous Metabolite Others
    α-D-Glucosamine 1-phosphate is an E.coli metabolite. α-D-Glucosamine 1-phosphate is one of the precursors of peptidoglycan synthesis .
    α-D-Glucosamine 1-phosphate
  • HY-177337
    N-Didesmethyladitoprim

    N-Didesmethyl-ADP

    		 Drug Metabolite Antifolate Bacterial Infection
    N-Didesmethyladitoprim is a metabolite of Aditoprime (HY-139743). Aditoprime is a selective bacterial dihydrofolate reductase (DHFR) inhibitor with IC50s of 47 and 520 nM for E.coli and L.casei DHFR , respectively. Aditoprime inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime has a broad-spectrum antibacterial activity and excellent pharmacokinetics .
    N-Didesmethyladitoprim
  • HY-148197
    Glutathionylspermidine

    		Endogenous Metabolite Others
    Glutathionylspermidine is a peptide and a metabolite of E. coli .
    Glutathionylspermidine
  • HY-113270
    Actinine

    γ-Butyrobetaine; Deoxycarnitine

    		 Endogenous Metabolite Metabolic Disease
    Actinine (γ-Butyrobetaine) is an amino acid betaine aminobutyric acid zwitterion. Actinine acts as both a human metabolite and a metabolite of E. coli .
    Actinine
  • HY-N8515B
    UDP-3-O-acyl-GlcNAc diammonium

    UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium

    		 Endogenous Metabolite Others
    UDP-3-O-acyl-GlcNAc diammonium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .
    UDP-3-O-acyl-GlcNAc diammonium
  • HY-N8515
    UDP-3-O-acyl-GlcNAc

    UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine

    		 Endogenous Metabolite Infection
    UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .
    UDP-3-O-acyl-GlcNAc
  • HY-W585865
    UDP-3-O-acyl-GlcNAc Tris

    UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris

    		 Endogenous Metabolite Infection
    UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) Tris is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .
    UDP-3-O-acyl-GlcNAc Tris
  • HY-N8515C
    UDP-3-O-acyl-GlcNAc disodium

    UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine disodium

    		 Endogenous Metabolite Infection Others
    UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) disodium is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway .
    UDP-3-O-acyl-GlcNAc disodium
  • HY-113247R
    trans-trans-Muconic acid (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease
    trans-trans-Muconic acid (Standard) is the analytical standard of trans-trans-Muconic acid. This product is intended for research and analytical applications. trans-trans-Muconic acid is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in human. trans-trans-Muconic acid is mutagenic in an E. coli assay .
    trans-trans-Muconic acid (Standard)
  • HY-N8060
    Orotidine 5′-monophosphate

    Orotidine monophosphate; Orotidylic acid

    		 Endogenous Metabolite Others
    Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of?uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase .
    Orotidine 5′-monophosphate
  • HY-N8301
    Ilicicolin F

    LL-Z 1272ζ

    		 Bacterial Infection
    Ilicicolin F is a fungal metabolite that has been found in Fusarium and has diverse biological activities. It inhibits T. vivax alternative oxidase and the E. coli ubiquinol oxidase cytochrome bo (IC50s=0.43 and 0.37 μM, respectively) but not the E. coli ubiquinol oxidase cytochrome bd (IC50=85 μM).2 Ilicicolin F is active against the fungi A. fumigatus and C. albicans (MICs=1.66-3.33 and 6.66-13.33 μg/mL, respectively). It is cytotoxic to HeLa cells with an EC50 value of 0.003 μg/mL.
    Ilicicolin F
  • HY-W751002
    Orthosporin

    (+)-Orthosporin

    		 Endogenous Metabolite Bacterial HIV Reverse Transcriptase Infection
    Orthosporin ((+)-Orthosporin), a phytotoxic isocoumarin compound, is a microbial secondary metabolite. Orthosporin can be isolated from the endophytic fungus Lasiodiplodia tbeobromae. Orthosporin has potent antibacterial activity against B. subtilis, E. coli and P. aeruginosa. Orthosporin also has antioxidant activity against DPPH radical and antiviral activities with inhibition of HIV-1 reverse transcriptase activity .
    Orthosporin
  • HY-N7307
    Pachybasin

    		Bacterial Infection
    Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively .
    Pachybasin
  • HY-N8256
    (–)-Mycousnine

    Mycousunin

    		 Fungal Infection
    (–)-Mycousnine is a microbial metabolite and derivative of Usnic Acid (HY-N0656) originally isolated from M. nawae that has antibacterial and antifungal activities. It is active against the Gram-positive bacteria B. subtilis, K. rhizophila, and S. aureus (MICs=4, 8, and 4 g/ml, respectively) but not the Gram-negative bacteria E. coli, S. typhimurium, and K. pneumoniae (MICs=>128 g/ml for all).2 (–)-Mycousnine is also active against the fungi T. mentagrophytes, T. rubrum, and C. albicans (MICs=25, 25, and 100 μg/mL, respectively).
    (–)-Mycousnine

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