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Results for "

Dipeptidyl peptidase-4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Dipeptidyl Peptidase (46) AMPK (2) Apoptosis (2) Aryl Hydrocarbon Receptor (1) COX (1) Cytochrome P450 (1) Drug Intermediate (1) Endogenous Metabolite (1) Estrogen Receptor/ERR (1) GCGR (3) Glutathione Peroxidase (2) Glycosidase (3) Interleukin Related (4) Isotope-Labeled Compounds (4) JNK (2) Lipoxygenase (1) Neuropeptide Y Receptor (1) NF-κB (2) NOD-like Receptor (NLR) (3) P-glycoprotein (1) p38 MAPK (2) PPAR (1) Reactive Oxygen Species (ROS) (2) Reference Standards (5) TNF Receptor (2) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (10) Inflammation/Immunology (5) Metabolic Disease (43) Neurological Disease (7)

By Targets:

Dipeptidyl Peptidase (46)

AMPK (2)

Apoptosis (2)

Aryl Hydrocarbon Receptor (1)

COX (1)

Cytochrome P450 (1)

Drug Intermediate (1)

Endogenous Metabolite (1)

Estrogen Receptor/ERR (1)

GCGR (3)

Glutathione Peroxidase (2)

Glycosidase (3)

Interleukin Related (4)

Isotope-Labeled Compounds (4)

JNK (2)

Lipoxygenase (1)

Neuropeptide Y Receptor (1)

NF-κB (2)

NOD-like Receptor (NLR) (3)

P-glycoprotein (1)

p38 MAPK (2)

PPAR (1)

Reactive Oxygen Species (ROS) (2)

Reference Standards (5)

TNF Receptor (2)

Toll-like Receptor (TLR) (1)

By Research Areas:

Cancer (4)

Cardiovascular Disease (10)

Inflammation/Immunology (5)

Metabolic Disease (43)

Neurological Disease (7)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Dipeptidyl Peptidase Kallikrein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14892A

Gemigliptin tartrate LC15-0444 tartrate	Dipeptidyl Peptidase	Metabolic Disease
Gemigliptin tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC₅₀ of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties. Gemigliptin tartrate can be used for the research of advanced glycation end products (AGE)-related diabetic complications .

HY-P2543

Neuropeptide Y (3-36) (human, rat)	Neuropeptide Y Receptor	Metabolic Disease
Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist. Neuropeptide Y (3-36) (human, rat) is a NPY metabolite formed from dipeptidyl peptidase-4 (DPP4). Neuropeptide Y (3-36) (human, rat) decreases release of norepinephrine via the Y2 receptor .

HY-10286

Dutogliptin PHX-1149 free base	Dipeptidyl Peptidase	Metabolic Disease
Dutogliptin (PHX-1149 free base) is an orally available, potent, and selective **dipeptidyl peptidase-4 (DPP4**) inhibitor for the treatment of type 2 diabetes mellitus.

HY-112668

Retagliptin phosphate 1 Publications Verification SP2086 phosphate	Dipeptidyl Peptidase	Metabolic Disease
Retagliptin phosphate (SP2086 phosphate) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. Retagliptin phosphate can be used for type 2 diabetes mellitus (T2DM) research .

HY-N10362

Ellipyrone B	Dipeptidyl Peptidase	Metabolic Disease
Ellipyrone B, an antihyperglycemic γ-pyrone enclosed macrocyclic polyketide, shows inhibition potential against **dipeptidyl peptidase-4 (IC₅₀=0.48 mM) .**

HY-N10360

Ellipyrone A	Dipeptidyl Peptidase	Metabolic Disease
Ellipyrone A, a γ-pyrone enclosed macrocyclic poyketide, shows inhibition potential against **dipeptidyl peptidase-4 (IC₅₀=0.35 mM). Ellipyrone A also has anti-carbolytic property against α-glucosidase (IC₅₀=0.74 mM) and α-amylase (IC₅₀=0.59 mM) .**

HY-N8134

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one	Dipeptidyl Peptidase	Metabolic Disease
2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with dipeptidyl peptidase-4 (DPP-4) and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities .

HY-175590

DPP-4-IN-17	Dipeptidyl Peptidase	Metabolic Disease
DPP-4-IN-17 is an orally active and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with an IC₅₀ value of 0.12 nM. DPP-4-IN-17 increases the enzyme's K_m value (75.73 μM vs. 27.18 μM of substrate alone) and reduces catalytic efficiency. DPP-4-IN-17 reduces blood glucose levels and reverses weight loss in Streptozotocin (STZ) (HY-13753)/Nicotinamide (NA) (HY-B0150)-induced diabetic rats. DPP-4-IN-17 can be used for the study of type 2 diabetes mellitus (T2DM) .

HY-10286A

Dutogliptin tartrate PHX-1149	Dipeptidyl Peptidase	Metabolic Disease
Dutogliptin tartrate (PHX-1149) is an orally available, potent, and selective **dipeptidyl peptidase-4 (DPP4**) inhibitor for the treatment of type 2 diabetes mellitus.

HY-170800

DPP-4-IN-15	Dipeptidyl Peptidase	Others
DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC₅₀ of 8.24 μM .

HY-112668A

Retagliptin 1 Publications Verification SP2086	Dipeptidyl Peptidase	Metabolic Disease
Retagliptin (SP2086) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. Retagliptin can be used for type 2 diabetes mellitus (T2DM) research .

HY-10285A

Saxagliptin hydrate 5 Publications Verification BMS-477118 hydrate	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin hydrate (BMS-477118 hydrate) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrate has the peotential for type 2 diabetes mellitus research .

HY-10285

Saxagliptin 5 Publications Verification BMS-477118	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-16448

Saxagliptin hydrochloride 5 Publications Verification BMS-477118 hydrochloride	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin hydrochloride (BMS-477118 hydrochloride) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrochloride has the peotential for type 2 diabetes mellitus research .

HY-163335

MPO-IN-7	Glutathione Peroxidase Dipeptidyl Peptidase Glycosidase	Cardiovascular Disease Inflammation/Immunology
MPO-IN-7 (compound MDC) is a myeloperoxidase inhibitor with the IC₅₀ values of 41 μM, 25 μM and 4.5 μM towards α-Glucosidase, dipeptidyl peptidase-4 and myeloperoxidase, respectively. MPO-IN-7 shows antioxidant and anti-inflammatory activity in vitro .

HY-112668B

Retagliptin hydrochloride SP2086 hydrochloride	Dipeptidyl Peptidase GCGR	Others
Retagliptin (SP2086) hydrochloride is a potent inhibitor of beta-amino acids and dipeptidyl peptidase-4 (DPP-4). Retagliptin (SP2086) hydrochloride inhibits type 2 diabetes and improves glycemic control by prolonging the action of intestinal hormones such as glucagon-like peptide-1 (GLP-1) .

HY-10285AR

Saxagliptin hydrate (Standard) BMS-477118 hydrate (Standard)	Reference Standards Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin (hydrate) (Standard) is the analytical standard of Saxagliptin (hydrate). This product is intended for research and analytical applications. Saxagliptin hydrate (BMS-477118 hydrate) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (Ki = 0.6-1.3 nM) inhibitor. Saxagliptin hydrate has the peotential for type 2 diabetes mellitus research .

HY-113015R

Stearoylethanolamide (Standard)	Endogenous Metabolite Reference Standards	Neurological Disease
Saxagliptin (hydrochloride) (Standard) is the analytical standard of Saxagliptin (hydrochloride). This product is intended for research and analytical applications. Saxagliptin hydrochloride (BMS-477118 hydrochloride) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (Ki = 0.6-1.3 nM) inhibitor. Saxagliptin hydrochloride has the peotential for type 2 diabetes mellitus research .

HY-16448R

Saxagliptin hydrochloride (Standard) BMS-477118 hydrochloride (Standard)	Reference Standards Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin (hydrochloride) (Standard) is the analytical standard of Saxagliptin (hydrochloride). This product is intended for research and analytical applications. Saxagliptin hydrochloride (BMS-477118 hydrochloride) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (Ki = 0.6-1.3 nM) inhibitor. Saxagliptin hydrochloride has the peotential for type 2 diabetes mellitus research .

HY-P1141

GLP-1(9-36)amide	GCGR	Metabolic Disease
GLP-1(9-36)amide is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide acts as an antagonist to the human pancreatic GLP-1 receptor .

HY-10285R

Saxagliptin (Standard) BMS-477118 (Standard)	Reference Standards Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin (Standard) is the analytical standard of Saxagliptin. This product is intended for research and analytical applications. Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-P1141A

GLP-1(9-36)amide TFA	GCGR	Metabolic Disease
GLP-1(9-36)amide TFA is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide TFA acts as an antagonist to the human pancreatic GLP-1 receptor .

HY-155704

Lyciumamide A	PPAR	Others
DPP-IV-IN-5 is isolated from the fruits of Lycium barbarum. DPP-IV-IN-5 exerts moderate agonistic activities for peroxisome proliferator-activated receptor (PPARγ) with EC₅₀ values of 10.09 - 44.26 μM and also presents inhibitory activity on dipeptidyl peptidase-4 (DPPIV) with an IC₅₀ value of 47.13 μM .

HY-14892

Gemigliptin LC15-0444	Dipeptidyl Peptidase	Metabolic Disease Cancer
Gemigliptin (LC15-0444 ) is a highly selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC₅₀ of 10.3 nM for human recombinant DPP-4. Gemigliptin exhibits potent anti-glycation properties. Gemigliptin can be used for the research of advanced glycation end products (AGE)-related diabetic complications .

HY-10285S2

Saxagliptin-13C2 BMS-477118-¹³C₂	Isotope-Labeled Compounds Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin- ¹³C₂ (BMS-477118- ¹³C₂) is ¹³C labeled Saxagliptin. Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-14892B

Gemigliptin tartrate hydrate LC15-0444 tartrate hydrate	Dipeptidyl Peptidase	Metabolic Disease
Gemigliptin (LC15-0444 ) tartrate hydrate is a selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC₅₀ of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate hydrate exhibits potent anti-glycation properties. Gemigliptin tartrate hydrate can be used for the research of advanced glycation end products (AGE)-related diabetic complications .

HY-163332

MPO-IN-6	Glycosidase Dipeptidyl Peptidase Glutathione Peroxidase	Cardiovascular Disease
MPO-IN-6 (compound ADC) is an electrophile with good antioxidant and anti-inflammatory properties. MPO-IN-6 is a myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD) inhibitor with IC₅₀s of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 is a potential cardiovascular preventive agent .

HY-10285S

Saxagliptin-15N,d2 hydrochloride BMS-477118-¹⁵N,d₂ Hydrochloride	Isotope-Labeled Compounds Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin-15N,d2 Hydrochloride (BMS-477118-15N,d2 Hydrochloride) is the ¹⁵N and deuterium labeled isotope of Saxagliptin (HY-10285). Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-174832

DPP-4-IN-16	Dipeptidyl Peptidase	Metabolic Disease
DPP-4-IN-16 (Compound 92) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor (IC₅₀=0.8 nM). DPP-4-IN-16 inhibits DPP-4-mediated degradation of incretins (e.g., GLP-1 and GIP) to promote insulin secretion and reduce blood glucose. DPP-4-IN-16 is promising for research of type 2 diabetes .

HY-110051

DPP4-In hydrochloride	Interleukin Related TNF Receptor NOD-like Receptor (NLR)	Inflammation/Immunology
DPP4-In (hydrochloride) is an inhibitor of dipeptidyl peptidase 4 (DPP4) that can reduce DPP4 expression .

HY-131250

N-Boc-Sitagliptin	Dipeptidyl Peptidase	Metabolic Disease
N-Boc-Sitagliptin is an intermediate in the synthesis of the dipeptidyl peptidase 4 (DPP-4) inhibitor Sitagliptin (HY-13749).

HY-Z3637

(–)-Sitagliptin carbamoyl glucuronide	Dipeptidyl Peptidase	Metabolic Disease
(–)-Sitagliptin carbamoyl glucuronide is a minor metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor Sitagliptin (HY-13749).

HY-176000

Sulphostin	Dipeptidyl Peptidase	Inflammation/Immunology Cancer
Sulphostin is a covalent inhibitor of dipeptidyl peptidase 4 (DPP4), dipeptidyl peptidase 9 (DPP9), and dipeptidyl peptidase 8 (DPP8) with IC₅₀ values of 79, 1392, 6930 nM, respectively. Sulphostin causes phosphosulfamate modification, irreversibly inhibits the enzyme activity. Sulphostin can be used for inflammation and cancer study .

HY-W003592A

L-Orinithine lactam hydrochloride	Drug Intermediate	Others
L-Orinithine lactam hydrochloride is a synthetic intermediate. L-Orinithine lactam (hydrochloride) can be used in the synthesis of dipeptidyl peptidase 4 (DPP-4) inhibitors, as well as signaling peptides .

HY-N4069

Lupinalbin A Boeravinone L	Estrogen Receptor/ERR Aryl Hydrocarbon Receptor Dipeptidyl Peptidase Glycosidase	Metabolic Disease
Lupinalbin A (Boeravinone L) is a dipeptidyl peptidase 4 (DPP4) and α-glucosidase inhibitor with IC₅₀ values of 45.2 and 53.4 µM, respectively. Lupinalbin A exhibits antidiabetic activity .

HY-A0299A

H-Gly-Pro-Hyp-OH acetate	Dipeptidyl Peptidase	Metabolic Disease
H-Gly-Pro-Hyp-OH acetate is a dipeptidyl peptidase 4 (DPP-4) inhibitor with an IC₅₀ value of 2.51 mM. H-Gly-Pro-Hyp-OH acetate is promising for research of diabetes .

HY-14877

Anagliptin 3 Publications Verification SK-0403	Dipeptidyl Peptidase	Cardiovascular Disease Metabolic Disease
Anagliptin (SK-0403) is a highly selective, potent, orally active inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC₅₀ of 3.8 nM, and less selective at DPP-8 and DDP-9 with IC₅₀s of 68 nM and 60 nM, respectively .

HY-14877A

Anagliptin hydrochloride SK-0403 hydrochloride	Dipeptidyl Peptidase	Cardiovascular Disease Metabolic Disease
Anagliptin (SK-0403) hydrochloride is a highly selective, potent, orally active inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC₅₀ of 3.8 nM, and less selective at DPP-8 and DDP-9 with IC₅₀s of 68 nM and 60 nM, respectively .

HY-15981

Omarigliptin MK-3102	Dipeptidyl Peptidase	Neurological Disease Metabolic Disease
Omarigliptin (MK-3102) is a potent, selective, orally active and cross the blood-brain barrier dipeptidyl peptidase 4 (DPP-4) inhibitor. Omarigliptin shows anti-parkinsonian activity. Omarigliptin has the neuroprotective effect to improve diabetes-associated cognitive dysfunction .

HY-N6079

Timosaponin A1	Lipoxygenase Dipeptidyl Peptidase COX	Metabolic Disease Cancer
Timosaponin A1, a natural steroidal saponin, is a 5-lipoxygenase (5-LO), COX-2, and dipeptidyl peptidase 4 (DPP-4) inhibitor with IC₅₀s of 3.29 µM, 36.43 µM, and 33.25 µM, respectively .

HY-170569

Cetagliptin	Dipeptidyl Peptidase Cytochrome P450 P-glycoprotein	Metabolic Disease
Cetagliptin is an orally active inhibitor for **dipeptidyl peptidase 4 (DPP-4) and CYP2D6 (IC₅₀ of 6 µM). Cetagliptin is a substrate for P-glycoprotein**. Cetagliptin reduces the GLP-1 degradation, maintains the level of postprandial blood sugar, and can be used in type 2 diabetes mellitus research .

HY-151383

DPP-4-IN-1	Dipeptidyl Peptidase	Metabolic Disease
DPP-4-IN-1 (compound d1) is a potent DPP-4 (dipeptidyl peptidase 4) inhibitor, with an IC₅₀of 49 nM. DPP-4-IN-1 is a structurally analogs of Alogliptin (HY-A0023A). DPP-4-IN-1 can be used for diabetes research .

HY-151384

DPP-4-IN-2	Dipeptidyl Peptidase	Metabolic Disease
DPP-4-IN-2 (compound b2) is a potent DPP-4 (dipeptidyl peptidase 4) inhibitor, with an IC₅₀of 79 nM. DPP-4-IN-2 is a structurally analogs of Alogliptin (HY-A0023A). DPP-4-IN-2 can be used for diabetes research .

HY-14877R

Anagliptin (Standard)	Dipeptidyl Peptidase	Cardiovascular Disease Metabolic Disease
Anagliptin (Standard) is the analytical standard of Anagliptin. This product is intended for research and analytical applications. Anagliptin (SK-0403) is a highly selective, potent, orally active inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC50 of 3.8 nM, and less selective at DPP-8 and DDP-9 with IC50s of 68 nM and 60 nM, respectively .

HY-15981R

Omarigliptin (Standard) MK-3102 (Standard)	Reference Standards Dipeptidyl Peptidase	Neurological Disease Metabolic Disease
Omarigliptin (Standard) is the analytical standard of Omarigliptin. This product is intended for research and analytical applications. Omarigliptin (MK-3102) is a potent, selective, orally active and cross the blood-brain barrier dipeptidyl peptidase 4 (DPP-4) inhibitor. Omarigliptin shows anti-parkinsonian activity. Omarigliptin has the neuroprotective effect to improve diabetes-associated cognitive dysfunction .

HY-14877S1

Anagliptin-d7 SK-0403₇	Isotope-Labeled Compounds Dipeptidyl Peptidase	Cardiovascular Disease Metabolic Disease
Anagliptin-d₇ (SK-0403-d₇) is deuterium labeled Anagliptin. Anagliptin (SK-0403) is a highly selective, potent, orally active inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC₅₀ of 3.8 nM, and less selective at DPP-8 and DDP-9 with IC₅₀s of 68 nM and 60 nM, respectively .

HY-14806A

Teneligliptin hydrobromide Maximum Cited Publications 6 Publications Verification MP-513 hydrobromide	Dipeptidyl Peptidase NOD-like Receptor (NLR) Interleukin Related AMPK Reactive Oxygen Species (ROS) Apoptosis p38 MAPK NF-κB JNK	Cardiovascular Disease Neurological Disease Metabolic Disease
Teneligliptin (MP-513) hydrobromide is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor (IC₅₀s: 0.37 and 0.29 nM for the human and rat DPP-4, respectively). Teneligliptin hydrobromide improves blood glucose levels and can be used in researches related to type 2 diabetes mellitus .

HY-14806

Teneligliptin Maximum Cited Publications 6 Publications Verification MP-513	Dipeptidyl Peptidase	Cardiovascular Disease Neurological Disease Metabolic Disease
Teneligliptin (MP-513) hydrobromide hydrate is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor (IC₅₀s: 0.37 and 0.29 nM for the human and rat DPP-4, respectively). Teneligliptin hydrobromide hydrate improves blood glucose levels and can be used in researches related to type 2 diabetes mellitus .

HY-14806B

Teneligliptin hydrobromide hydrate Maximum Cited Publications 6 Publications Verification MP-513 hydrobromide hydrate	NOD-like Receptor (NLR) Interleukin Related AMPK Reactive Oxygen Species (ROS) Toll-like Receptor (TLR) NF-κB JNK p38 MAPK Apoptosis	Cardiovascular Disease Neurological Disease Metabolic Disease
Teneligliptin (MP-513) hydrobromide hydrate is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor (IC₅₀s: 0.37 and 0.29 nM for the human and rat DPP-4, respectively). Teneligliptin hydrobromide hydrate improves blood glucose levels and can be used in researches related to type 2 diabetes mellitus .

HY-158315

NZ-97	Dipeptidyl Peptidase	Inflammation/Immunology
NZ-97 is an inhibitor for dipeptidyl peptidase 4 (DPP4) with an IC₅₀ of 18 nM. NZ-97 exhibits a low initial plasma exposure with C_max of 0.13 µM, which is eliminated in 8 h. NZ-97 ameliorates damage in the Lipopolysaccharides (HY-D1056)-induced lung injury and Bleomycin (HY-108345)-induced lung fibrosis in mice model .

Cat. No.	Product Name	Target	Research Area

HY-P2543

Neuropeptide Y (3-36) (human, rat)	Neuropeptide Y Receptor	Metabolic Disease
Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist. Neuropeptide Y (3-36) (human, rat) is a NPY metabolite formed from dipeptidyl peptidase-4 (DPP4). Neuropeptide Y (3-36) (human, rat) decreases release of norepinephrine via the Y2 receptor .

HY-P1141

GLP-1(9-36)amide	GCGR	Metabolic Disease
GLP-1(9-36)amide is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide acts as an antagonist to the human pancreatic GLP-1 receptor .

HY-P1141A

GLP-1(9-36)amide TFA	GCGR	Metabolic Disease
GLP-1(9-36)amide TFA is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide TFA acts as an antagonist to the human pancreatic GLP-1 receptor .

Species:	Human (4) Mouse (2) Cynomolgus (3)
Tag:	His (4) Tag Free (2) Avi (1) Fc (3)
Source:	HEK293 (9)

Cat. No.	Compare	Product Name	Species	Source

HY-P75429

	*CD26/Dipeptidyl* Peptidase 4 Protein, Mouse (HEK293, Fc)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Mouse	HEK293
	CD26/dipeptidyl peptidase 4 is a key cell surface receptor for T cell activation. It binds to ADA, CAV1, IGF2R and PTPRC to promote T cell proliferation and NF-kappa-B activation. CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P72975

	*CD26/Dipeptidyl* Peptidase 4 Protein, Human (HEK293)** 2 Publications Verification Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Human	HEK293
	The CD26/dipeptidyl peptidase 4 protein is a cell surface glycoprotein receptor that induces T cell proliferation and NF-kappa-B activation. CD26 also works with FAP to promote pericellular proteolysis, endothelial cell migration, and invasion of the extracellular matrix. CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293) is the recombinant human-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with tag free.

HY-P72976

	*CD26/Dipeptidyl* Peptidase 4 Protein, Human (HEK293, Fc)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Human	HEK293
	The CD26/dipeptidyl peptidase 4 protein is a cell surface glycoprotein receptor that induces T cell proliferation and NF-kappa-B activation. CD26 also works with FAP to promote pericellular proteolysis, endothelial cell migration, and invasion of the extracellular matrix. CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, Fc) is the recombinant human-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P76876

	*CD26/Dipeptidyl* Peptidase 4 Protein, Cynomolgus (HEK293, His)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Cynomolgus	HEK293
	CD26/Dipeptidyl Peptidase 4 Protein is a serine membrane anchored exopeptidase, belonging to dipeptidyl peptidase (DPP) family. CD26/Dipeptidyl Peptidase 4 Protein is widely expressed in a variety of tissues and many cells. CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76877

	*CD26/Dipeptidyl* Peptidase 4 Protein, Cynomolgus (HEK293, Fc)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Cynomolgus	HEK293
	CD26/Dipeptidyl Peptidase 4 Protein is a serine membrane anchored exopeptidase, belonging to dipeptidyl peptidase (DPP) family. CD26/Dipeptidyl Peptidase 4 Protein is widely expressed in a variety of tissues and many cells. CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P70017

	*CD26/Dipeptidyl* Peptidase 4 Protein, Human (HEK293, His)** rHuDipeptidyl peptidase 4/CD26, His; Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26	Human	HEK293
	The CD26/dipeptidyl peptidase 4 protein is a cell surface glycoprotein receptor that induces T cell proliferation and NF-kappa-B activation. CD26 also works with FAP to promote pericellular proteolysis, endothelial cell migration, and invasion of the extracellular matrix. CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, His) is the recombinant human-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76875

	*CD26/Dipeptidyl* Peptidase 4 Protein, Cynomolgus (HEK293)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Cynomolgus	HEK293
	CD26/Dipeptidyl Peptidase 4 Protein is a serine membrane anchored exopeptidase, belonging to dipeptidyl peptidase (DPP) family. CD26/Dipeptidyl Peptidase 4 Protein is widely expressed in a variety of tissues and many cells. CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293) is the recombinant cynomolgus-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with tag free.

HY-P705426

	*CD26/Dipeptidyl* Peptidase 4 Protein, Mouse (HEK293, His)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Mouse	HEK293

HY-P705417

	*CD26/Dipeptidyl* Peptidase 4 Protein, Human (Biotinylated, HEK293, His-Avi)** Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Human	HEK293

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Cat. No.	Product Name	Chemical Structure

HY-10285S2

Saxagliptin-13C2
Saxagliptin- ¹³C₂ (BMS-477118- ¹³C₂) is ¹³C labeled Saxagliptin. Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-10285S

Saxagliptin-15N,d2 hydrochloride
Saxagliptin-15N,d2 Hydrochloride (BMS-477118-15N,d2 Hydrochloride) is the ¹⁵N and deuterium labeled isotope of Saxagliptin (HY-10285). Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-14877S1

Anagliptin-d7
Anagliptin-d₇ (SK-0403-d₇) is deuterium labeled Anagliptin. Anagliptin (SK-0403) is a highly selective, potent, orally active inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC₅₀ of 3.8 nM, and less selective at DPP-8 and DDP-9 with IC₅₀s of 68 nM and 60 nM, respectively .

HY-14806S2

Teneligliptin-d5

Teneligliptin-d₅ (MP-513-d₅) is deuterium labeled Teneligliptin. Teneligliptin (MP-513) hydrobromide hydrate is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor (IC₅₀s: 0.37 and 0.29 nM for the human and rat DPP-4, respectively). Teneligliptin hydrobromide hydrate improves blood glucose levels and can be used in researches related to type 2 diabetes mellitus .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82766

	CD26 Antibody (YA2511) DPP4; ADCP2; CD26; Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26; TP103; CD26	WB	Human, Mouse, Rat
	CD26 Antibody (YA2511) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD26.

HY-P81529

	CD26 Antibody (YA1274) ADCP2, CD26; DPP4; Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2 (ADCP-2); Dipeptidyl peptidase IV (DPP IV); T-cell activation antigen CD26; TP103	IHC-P	Human
	CD26 Antibody (YA1274) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD26.

HY-P84979

	CD26 Antibody (YA4671) DPP4; ADCP2; CD26; Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26; TP103; CD26; CD26 nanobody	ELISA, FC	Human
	CD26 Antibody (YA4671) is a mouse-derived and non-conjugated monoclonal antibody, targeting to CD26. It can be applicated for ELISA, FC assays, in the background of human.