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Results for "

Dioscorea. bulbifera L

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0429
    Diosbulbin B
    1 Publications Verification

    		 Apoptosis MDM-2/p53 Bcl-2 Family CDK Cancer
    Diosbulbin B, a diterpene lactone, is an anticancer agent. Diosbulbin B is an orally active component of Dioscorea. bulbifera L. Diosbulbin B can inhibit cell proliferation, induce G0/G1 phase arrest and apoptosis. Diosbulbin B can induce autophagy and mitochondrial dysfunction. Diosbulbin B can induce liver injury. Diosbulbin B can be used for the research of cancer, such as non-small cell lung cancer (NSCLC) .
    Diosbulbin B
  • HY-N7047
    8-Epidiosbulbin E acetate

    		Bacterial Infection
    8-Epidiosbulbin E acetate, a furanoid, is abundant in Dioscorea bulbifera L.. 8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. 8-Epidiosbulbin E acetate induces liver injury in mice .
    8-Epidiosbulbin E acetate
  • HY-N3768
    Diosbulbin L

    		Others Others
    Diosbulbin L is a Diterpenoids product that can be isolated from the rhizomes of Dioscorea bulbifera. .
    Diosbulbin L
  • HY-N3767
    Diosbulbin J

    		Others Others
    Diosbulbin J is a Diterpenoids product that can be isolated from the roots of Dioscorea bulbifera .
    Diosbulbin J
  • HY-N3765
    Diosbulbin D

    		Apoptosis Metabolic Disease
    Diosbulbin D is a potential hepatotoxic compound that can be isolated from Dioscorea bulbifera L.. Diosbulbin D induces apoptosis in L-02 cells .
    Diosbulbin D
  • HY-N3764
    Diosbulbin C

    		Akt Dihydrofolate reductase (DHFR) Endogenous Metabolite Others
    Diosbulbin C is a diterpene lactone component, which can be extracted from traditional Chinese medicine Dioscorea bulbifera L.. Diosbulbin C possesses high anticancer activity in non-small cell lung cancer (NSCLC). Diosbulbin C could induce cell cycle arrest at G0/G1 phase in NSCLC. Diosbulbin C also inhibits the proliferation of NSCLC cells, possibly by downregulating the expression/activation of AKT, DHFR, and TYMS .
    Diosbulbin C

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