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Results for "

Degradable Kinome

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-137342
    SB1-G-187

    		PROTACs Src IRAK Bcr-Abl Cancer
    SB1-G-187 is a GNF-7-based multi-kinase PROTAC degrader that induces potent degradation of YES1, IRAK1, LYN, etc. SB1-G-187 mediates kinase degradation in a partially p97/VCP-dependent manner. SB1-G-187 can be utilized to develop new strategies for treating difficult diseases (Pink: multi-kinase ligand (HY-125142); Blue: CRBN ligand (HY-A0003)) .
    SB1-G-187

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