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Deglycobleomycin

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-174276
    Deglycobleomycin

    		DNA/RNA Synthesis Metabolic Disease
    Deglycobleomycin is an RNA cleavage agent targeting r(CUG) repeat sequences. Deglycobleomycin can selectively cleave r(CUG) exp after binding to a small molecule that recognizes r(CUG) exp. The DNA cleavage efficiency of deglycobleomycin is much lower than that of Bleomycin A5 (Pingyangmycin) (HY-N10470). However, deglycobleomycin has enhanced selective cleavage activity against r(CUG) exp. Deglycobleomycin can be used to study diseases related to r(CUG) exp expansion (such as myotonic dystrophy type 1); and for the development of drugs that precisely target and cleave pathogenic RNA .
    Deglycobleomycin

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