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Dealkylation

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-77910
    4-(4-Bromophenyl)-4-hydroxypiperidine

    BPHP

    		 Drug Metabolite Neurological Disease
    4-(4-Bromophenyl)-4-hydroxypiperidine (BPHP) is a metabolite of Bromperidol (BRO) (HY-B0901) and is produced by N-dealkylation of BRO .
    4-(4-Bromophenyl)-4-hydroxypiperidine
  • HY-177482
    Pro-PTX

    		Drug Intermediate Others
    Pro-PTX is an inactive prodrug of Paclitaxel (HY-B0015). Pro-PTX does not show cytotoxicity against cancer cells, such as A549, U87 and HBVP cells. Pro-PTX can be converted into Paclitaxel through dealkylation catalyzed by Pd nanosheets in agarose and alginate hydrogels .
    Pro-PTX
  • HY-119536
    Norsufentanil

    		Cytochrome P450 Neurological Disease
    Sufentanil is a potent synthetic opioid analgesic. Norsufentanil, a metabolite of sufentanil, is produced by the oxidative N-dealkylation of the liver cytochrome P450 isomer. Norsufentanil has analgesic activity .
    Norsufentanil
  • HY-W707158
    Norfenfluramine hydrochloride

    (±)-Norfenfluramine hydrochloride

    		 Drug Metabolite Neurological Disease
    Norfenfluramine hydrochloride ((±)-Norfenfluramine hydrochloride) is the primary metabolite of Fenfluramine, formed through N-dealkylation of Fenfluramine. Norfenfluramine hydrochloride is also a potent anorexiant. Norfenfluramine hydrochloride can regulate serotonergic neurotransmission. In addition, Norfenfluramine hydrochloride exhibits sedative effects after acute administration .
    Norfenfluramine hydrochloride
  • HY-15899
    Des(benzylpyridyl) Atazanavir

    		HIV Protease HIV Drug Metabolite Infection
    Des(benzylpyridyl) Atazanavir (compound M1) is a N-dealkylation product of Atazanavir (HY-17367) metabolite. Atazanavir is a highly selective HIV-1 protease inhibitor. Des(benzylpyridyl) Atazanavir may contribute to the effectiveness Atazanavir but also to the toxicity and interactions. Des(benzylpyridyl) Atazanavir can be used for further research of Atazanavir effects .
    Des(benzylpyridyl) Atazanavir

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