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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
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DPC-X3 cells

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175589
    XSJ81

    		Topoisomerase Apoptosis Bcl-2 Family Cancer
    XSJ81 is an orally active anti-cancer agent. XSJ81 significantly inhibits the proliferation of ampullary carcinoma (AC) DPC-X3 cells with an IC50 of 0.655 μM. XSJ81 inhibits the colony formation, arrests cell cycle at the G2/M phase and inhibits the migration in DPC-X3 cells. XSJ81 induces DNA damage and apoptosis in DPC-X3 cells. XSJ81 demonstrates significant anti-tumor efficacy in mice bearing DPC-X3 xenografts. XSJ81 can be used for the study of ampullary carcinoma .
    XSJ81

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