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DNA gyrase B-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147945
    DNA gyrase B-IN-1

    		DNA/RNA Synthesis Bacterial Infection
    DNA gyrase B-IN-1 (compound 13) is a potent DNA gyrase B inhibitor. DNA gyrase B-IN-1 shows inhibition of P. aeruginosa DNA gyrase B, with an IC50 of 2.2 μM. DNA gyrase B-IN-1 has good binding affinity and stability .
    DNA gyrase B-IN-1
  • HY-B0395E
    (1S,2R,7S)-Sitafloxacin

    (1S,2R,7S)-DU-6859a; DU-6856

    		 Antibiotic Bacterial Topoisomerase Infection
    (1S,2R,7S)-Sitafloxacin (DU-6856) is an enantiomer of Sitafloxacin (HY-B0395). (1S,2R,7S)-Sitafloxacin is a topoisomerase inhibitor. (1S,2R,7S)-Sitafloxacin is an antibiotic. (1S,2R,7S)-Sitafloxacin has inhibitory activity against Escherichia coli DNA gyrase (IC50 0.18 μg/mL) and Staphylococcus aureus topoisomerase IV. (1S,2R,7S)-Sitafloxacin has antibacterial activity and can be used in the study of various bacterial infections .
    (1S,2R,7S)-Sitafloxacin

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