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Results for "

DGK-zeta-inhibitor

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-156574
    DGKζ-IN-4

    		DGK Cancer
    DGKζ-IN-4 is a DGK-zeta inhibitor. DGKζ-IN-4 can be used as an active component of pharmaceutical compositions. DGKζ-IN-4 is used to treat cancers associated with immune cell activation or cancers resistant to anti-PD-1 antibody/anti-PD-11 antibody treatment .
    DGKζ-IN-4
  • HY-153343
    Veludacigib
    3 Publications Verification

    BAY 2965501

    		 DGK Cancer
    BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer .
    Veludacigib
  • HY-170427
    DGKζ-IN-10

    		DGK Inflammation/Immunology
    DGKζ-IN-10 (compound 349) is a DGKζ inhibitor, with an IC50 ≤200 nM .
    DGKζ-IN-10
  • HY-170426
    DGKζ-IN-9

    		DGK Inflammation/Immunology
    DGKζ-IN-9 (compound 73) is a DGKζ inhibitor, with an IC50 ≤200 nM .
    DGKζ-IN-9
  • HY-160123
    DGKζ-IN-5

    		DGK Cancer
    DGKζ-IN-5 is a DGKζ inhibitor (WO2023125681A1; compound A27a) .
    DGKζ-IN-5
  • HY-156572
    DGKζ-IN-3

    		DGK Cancer
    DGKζ-IN-3 is a DGK-zeta-inhibitor. DGKζ-IN-3 is used in liquid and solid cancer and other diacylglycerol kinase zeta (DGK-ζ) regulation of diseases .
    DGKζ-IN-3
  • HY-169318
    DGKζ-IN-7

    		DGK Interleukin Related Inflammation/Immunology Cancer
    DGKζ-IN-7 (compound 97) is an oral active DGKζ inhibitor with the IC50 of 33.4 nM. DGKζ-IN-6 inhibits the secretion of IL-2 and can be used for study of cancer and autoimmune diseases .
    DGKζ-IN-7
  • HY-169317
    DGKζ-IN-6

    		DGK Interleukin Related Inflammation/Immunology Cancer
    DGKζ-IN-6 (compound 40) is an oral active DGKζ inhibitor with the IC50 of 45.5 nM. DGKζ-IN-6 inhibits the secretion of IL-2 and can be used for study of cancer and autoimmune diseases .
    DGKζ-IN-6
  • HY-178327
    DGKα&ζ-IN-2

    		DGK Interleukin Related Inflammation/Immunology Cancer
    DGKα/ζ-IN-2 is a potent, orally active and selective dual DGKα/ζ inhibitor with IC50 values of 23 nM (DGKα) and 1.2 nM (DGKζ). DGKα/ζ-IN-2 exhibits selectivity over other DGK isoforms, such as DGKβ and DGKγ. DGKα/ζ-IN-2 shows robust and dose-dependent immune activation in the presence of antigen presentation in an OT-1 murine model. DGKα/ζ-IN-2 can be used for antitumor immunity .
    DGKα&ζ-IN-2
  • HY-159649
    BMS-986408

    		DGK Cancer
    BMS-986408 is an orally active dual DGK α/ζ inhibitor that restores T cell-mediated anti-tumor immunity by enhancing T cell signaling .
    BMS-986408
  • HY-153343A
    (S)-Veludacigib

    (S)-BAY 2965501

    		 DGK ERK Cancer
    (S)-BAY 2965501 is the left-handed isomer of BAY 2965501 (HY-153343). BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer .
    (S)-Veludacigib

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