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DGAT-1 inhibitor 2 (Standard)

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-50670R
    DGAT-1 inhibitor 2 (Standard)

    		Reference Standards Acyltransferase Reactive Oxygen Species (ROS) HSP PERK Metabolic Disease
    DGAT-1 inhibitor 2 (Standard) is the analytical standard of DGAT-1 inhibitor 2 (HY-50670). This product is intended for research and analytical applications. DGAT-1 inhibitor 2 is an orally active DGAT-1 inhibitor with IC50 values of 15 nM and 9 nM for human DGAT-1 and rat DGAT-1, respectively. DGAT-1 inhibitor 2 increases ROS concentration, GRP78, and PERK protein abundance. DGAT-1 inhibitor 2 increases SREBF1, CPT1A, and MTTP mRNA in fatty acid-treated cells. DGAT-1 inhibitor 2 improves obesity .
    DGAT-1 inhibitor 2 (Standard)

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