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Results for "

DAB452

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

3

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-A0248A
    Polymyxin B1
    1 Publications Verification

    		 Bacterial Infection
    Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
    Polymyxin B1
  • HY-W966282
    Aplindore

    DAB-452

    		 Dopamine Receptor Neurological Disease
    Aplindore (DAB-452) is a potent agonist of the dopamine D2 receptor, with the pKi of 9.1. Aplindore plays an important role in Parkinson's disease research .
    Aplindore
  • HY-129507
    Aplindore fumarate

    DAB-452 fumarate

    		 Dopamine Receptor Neurological Disease
    Aplindore fumarate (DAB-452 fumarate) is a dopamine D2 receptor partial agonist. Aplindore fumarate could be used in studies of Parkinson's disease and schizophrenia .
    Aplindore fumarate
  • HY-107027
    Polymyxin E2 sulfate

    		Antibiotic Infection
    Polymyxin E2 sulfate is an antibiotic produced by the soil bacterium Bacillus polymyxa .
    Polymyxin E2 sulfate
  • HY-P11232
    NAB815

    		Toll-like Receptor (TLR) Bacterial Infection
    NAB815 is a specific inhibitor of the Stx2a (Kd = 0.01 μM)/TLR4 interaction. NAB815 inhibits the neutrophil/Stx2a interaction (IC50 = 0.057 μg/mL). NAB815 inhibits the formation of Stx2-containing extracellular vesicles (EVs) produced by leukocytes and platelets and reduces their toxic effects in cellular (Vero cells) and animal models (CD-1 mice). NAB815 reduces bacterial loads in the kidneys, urine, and bladders of Escherichia coli-infected mice. NAB815 is useful in the study of hemolytic uremic syndrome (HUS) .
    NAB815

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