Cxcl9

By Targets:	Apoptosis (1) Arrestin (1) c-Fms (1) C-type Lectin-like Receptors (CTLRs) (1) CXCR (4) Fungal (1) G Protein-coupled Receptor Kinase (GRK) (1) IFNAR (1) Interleukin Related (1) JAK (2) Small Interfering RNA (siRNA) (1) STAT (1) TNF Receptor (1)
By Research Areas:	Cancer (5) Infection (1) Inflammation/Immunology (5)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990255

*Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5)*	CXCR	Inflammation/Immunology Cancer
Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) is an anti-mouse *CXCL9/MIG* IgG monoclonal antibody. Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) can reduce tumor infiltration of CD8 ⁺ cytotoxic T cells (CTLs). Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) can prolong the survival of transplanted hearts. Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) can be used for research on immunology and cancer such as prostate cancer .

HY-W505771

Seselin	Fungal	Infection Inflammation/Immunology Cancer
Seselin is an anticancer, antinociceptive, anti-inflammatory and antifungal agent. Seselin is orally active .

HY-RS03396

CXCL9 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CXCL9 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCL9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CXCL9 Human Pre-designed siRNA Set A CXCL9 Human Pre-designed siRNA Set A

HY-P10301

CXCL9(74-103)	CXCR	Cancer
CXCL9(74-103) is a derivative peptide of CXCL9 that has a high affinity for glycosaminoglycans (GAGs) and can bind to GAGs. CXCL9(74-103) possesses anti-angiogenic properties, capable of reducing EGF, VEGF165, and FGF-2-mediated angiogenesis processes in vitro, without exhibiting cytotoxicity .

HY-167884

PF-1367550	JAK	Inflammation/Immunology
PF-1367550 is a pan-JAK inhibitor. PF-1367550 can decrease the levels of release of CXCL9, CXCL10 and CXCL11 from primary airway epithelial cells .

HY-162415

CSF1R-IN-22	c-Fms Apoptosis	Cancer
CSF1R-IN-22 (Compound C19) is an orally effective CSF-1R selective inhibitor (IC₅₀<6 nM). CSF1R-IN-22 enhances the secretion of CXCL9 from M2 macrophages, increases CD8 ⁺ T cell infiltration. CSF1R-IN-22 boosts anti-tumor immune responses of anti-PD-1, and induces apoptosis in tumor cells. CSF1R-IN-22 can effectively reprogram M2-like TAMs (tumor-associated macrophages) to the M1 phenotype and reshape the TME by inducing the recruitment of CD8 ⁺ T cells into tumors and reducing the infiltration of immunosuppressive Tregs and MDSCs .

HY-P991610

S-095029 Sym025	C-type Lectin-like Receptors (CTLRs)	Cancer
S-095029 is a humanized IgG1 monoclonal antibody inhibitor targeting NKG2A. S-095029 significantly attenuates Fc-effector functions, inhibits the interaction with its ligand HLA-E, and increases the antibody-dependent cellular cytotoxicity mediated by other Fc-competent mAbs. S-095029 has a potent antitumor activity with enhancement of killing activity and cytokine secretion (IFNγ, TNF-α and CXCL9) of NK and γδ T-cells in co-culture with cancer cells .

HY-165428

SCH-900875	CXCR Arrestin	Inflammation/Immunology
SCH-900875 is an orally active, brain-penetrant and selective CXCR3 receptor inhibitor, which also shows high selectivity over CXCR1 and CXCR2 receptors. SCH-900875 binds to CXCR3, blocking the binding of ligands CXCL9, CXCL10, and CXCL11, inhibiting downstream G protein and β-arrestin signaling pathways to suppress inflammatory cell migration. SCH-900875 is promising for research of autoimmune diseases (rheumatoid arthritis, multiple sclerosis) and inflammatory disorders (psoriasis, inflammatory bowel disease) .

HY-168971

Paeoniflorin-6′-O-benzene sulfonate CP-25	IFNAR STAT TNF Receptor Interleukin Related CXCR JAK G Protein-coupled Receptor Kinase (GRK)	Inflammation/Immunology
Paeoniflorin-6′-O-benzene sulfonate (CP-25) is the inhibitor for G protein-coupled receptor kinase 2 (GRK2) that inhibits the translocation of GRK2 to the cell membrane, inhibits JAK1/STAT3 signaling pathway. Paeoniflorin-6′-O-benzene sulfonate inhibits IL-17A/CXCL2-induced proliferation of HaCaT. Paeoniflorin-6′-O-benzene sulfonate reduces the levels of inflammatory factors and chemokines such as IL-17A, IL-17F, IFN-γ, TNF-α, IL-22, IL-23, CXCL2, CXCL3 and CXCL9, alleviates Imiquimod (HY-B0180)-induced psoriasis in mouse model .

Cat. No.	Product Name	Target	Research Area

HY-P10301

CXCL9(74-103)	CXCR	Cancer
CXCL9(74-103) is a derivative peptide of CXCL9 that has a high affinity for glycosaminoglycans (GAGs) and can bind to GAGs. CXCL9(74-103) possesses anti-angiogenic properties, capable of reducing EGF, VEGF165, and FGF-2-mediated angiogenesis processes in vitro, without exhibiting cytotoxicity .

Cat. No.	Product Name	Target	Research Area

HY-P990255

*Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5)*	CXCR	Inflammation/Immunology Cancer
Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) is an anti-mouse *CXCL9/MIG* IgG monoclonal antibody. Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) can reduce tumor infiltration of CD8 ⁺ cytotoxic T cells (CTLs). Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) can prolong the survival of transplanted hearts. Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) can be used for research on immunology and cancer such as prostate cancer .

HY-P991610

S-095029 Sym025	C-type Lectin-like Receptors (CTLRs)	Cancer
S-095029 is a humanized IgG1 monoclonal antibody inhibitor targeting NKG2A. S-095029 significantly attenuates Fc-effector functions, inhibits the interaction with its ligand HLA-E, and increases the antibody-dependent cellular cytotoxicity mediated by other Fc-competent mAbs. S-095029 has a potent antitumor activity with enhancement of killing activity and cytokine secretion (IFNγ, TNF-α and CXCL9) of NK and γδ T-cells in co-culture with cancer cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W505771

Seselin	Structural Classification Flavonoids Source classification Ficus erecta Thunb. var. beecheyana (Hook.et Arn.) King Plants Moraceae Other Flavonoids	Fungal
Seselin is an anticancer, antinociceptive, anti-inflammatory and antifungal agent. Seselin is orally active .

HY-167884

PF-1367550	Structural Classification Alkaloids Aristolochia debilis Sieb. et Zucc. Source classification Plants Aristolochiaceae	JAK
PF-1367550 is a pan-JAK inhibitor. PF-1367550 can decrease the levels of release of CXCL9, CXCL10 and CXCL11 from primary airway epithelial cells .

Recombinant Proteins Recommended:

CXCL9

Species:	Human (3) Rhesus Macaque (1) Mouse (1) Rabbit (1) Pig (1)
Tag:	His (5) SUMO (1) Tag Free (2)
Source:	HEK293 (2) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source

HY-P72675

	*MIG/CXCL9* Protein, Human (HEK293, His)** C-X-C motif chemokine 9; HuMIG; MIG; Cxcl9; CMK; SCYB9	Human	HEK293
	CXCL9, also known as MIG, is one member of the ELR-negative CXC chemokine subfamily, and can be induced by IFN-γ. CXCL9 binds to its receptor CXCR3 and can recruit CXCR3+ cells, such as effector T cells, regulatory T cells (Tregs) and CD8+ cytotoxic T cells. CXCL9 is involved in immunoregulatory and inflammatory processes, but it also play a key role in tumor growth, angiogenesis, and metastasis. MIG/CXCL9 Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 103 amino acids (T23-T125).

HY-P70008

	*MIG/CXCL9* Protein, Mouse (HEK293, His)** 1 Publications Verification rMuC-X-C motif chemokine 9/Cxcl9, His; C-X-C motif chemokine 9; Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; MIG; MuMIG; Protein m119; Small-inducible cytokine B9; Cxcl9; Mig; Scyb9	Mouse	HEK293
	CXCL9, also known as MIG, is one member of the ELR-negative CXC chemokine subfamily, and can be induced by IFN-γ. CXCL9 binds to its receptor CXCR3 and can recruit CXCR3+ cells, such as effector T cells, regulatory T cells (Tregs) and CD8+ cytotoxic T cells. CXCL9 is involved in immunoregulatory and inflammatory processes, but it also play a key role in tumor growth, angiogenesis, and metastasis. MIG/CXCL9 Protein, Mouse (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags.

HY-P7253

	*MIG/CXCL9* Protein, Human** 1 Publications Verification rHuMIG/Cxcl9; C-X-C motif chemokine 9; SCYB9	Human	E. coli
	CXCL9, also known as MIG, is one member of the ELR-negative CXC chemokine subfamily, and can be induced by IFN-γ. CXCL9 binds to its receptor CXCR3 and can recruit CXCR3+ cells, such as effector T cells, regulatory T cells (Tregs) and CD8+ cytotoxic T cells. CXCL9 is involved in immunoregulatory and inflammatory processes, but it also play a key role in tumor growth, angiogenesis, and metastasis. MIG/CXCL9 Protein, Human is produced in E.coil, and consists of 103 amino acids (T23-T125).

HY-P700050AF

	*Animal-Free MIG/CXCL9* Protein, Human (His)** MIG/Cxcl9; C-X-C motif chemokine 9; SCYB9	Human	E. coli
	MIG, also known as CXCL9 protein, occurs as a cytokine that affects the growth, movement, or activation state of cells involved in immune and inflammatory responses. Specifically, it acts as a potent chemoattractant for activated T cells, coordinating their migration. Animal-Free MIG/CXCL9 Protein, Human (His) is the recombinant human-derived animal-FreeMIG/CXCL9 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P77086

	*MIG/CXCL9* Protein, Rhesus Macaque** C-X-C motif chemokine 9; HuMIG; MIG; Cxcl9; CMK; SCYB9	Rhesus Macaque	E. coli
	CXCL9, also known as MIG, is one member of the ELR-negative CXC chemokine subfamily, and can be induced by IFN-γ. CXCL9 binds to its receptor CXCR3 and can recruit CXCR3+ cells, such as effector T cells, regulatory T cells (Tregs) and CD8+ cytotoxic T cells. CXCL9 is involved in immunoregulatory and inflammatory processes, but it also play a key role in tumor growth, angiogenesis, and metastasis. MIG/CXCL9 Protein, Rhesus Macaque is produced in E.coil, and consists of 103 amino acids (T23-T125).

HY-P700553

	*MIG/CXCL9* Protein, Rabbit (His-SUMO)** C-X-C motif chemokine 9; HuMIG; MIG; Cxcl9; CMK; SCYB9	Rabbit	E. coli
	The MIG/CXCL9 protein is part of the intercrine α family and is critical for chemokines involved in intercellular communication and immune responses. In this family, MIG/CXCL9 may play a key role in regulating inflammatory processes and influencing cellular interactions. MIG/CXCL9 Protein, Rabbit (His-SUMO) is the recombinant Rabbit-derived MIG/CXCL9 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P700235AF

	*Animal-Free MIG/CXCL9* Protein, Pig (His)** C-X-C motif chemokine 9; Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; MIG; MuMIG; Protein m119; Small-inducible cytokine B9; Cxcl9; Mig; Scyb9	Pig	E. coli
	The CXCL9 protein is part of the intercrine alpha family of chemokines critical for cell-to-cell communication and immune responses. In this family, CXCL9 may play a key role in regulating inflammatory processes and influencing cellular interactions. Animal-Free MIG/CXCL9 Protein, Pig (His) is the recombinant pig-derived animal-Free CXCL9 protein, expressed by E. coli , with N-His labeled tag.This product is for cell culture use only.

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HY-P84505

	CXCL9 Antibody (YA4202) CMK; MIG; Humig; SCYB9; crg-10	ICC/IF, FC, ELISA, ELISA	Human
	CXCL9 Antibody (YA4202) is a mouse-derived and non-conjugated IgG2a antibody, targeting to CXCL9. It can be applicated for ICC/IF, FC, ELISA, ELISA assays, in the background of human.

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Cat. No.	Product Name		Classification

HY-RS03396

CXCL9 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CXCL9 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCL9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cxcl9

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