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Results for "

Capivasertib

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15431
    Capivasertib
    60+ Cited Publications

    AZD5363

    		 Akt Autophagy Cancer
    Capivasertib (AZD5363) is an orally active and potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively.
    Capivasertib
  • HY-164460
    AZD1897

    		Pim Cancer
    AZD1897 is a PIM1, PIM2, and PIM3 inhibitor with IC50 values of less than 3 nM for these three PIM kinases. AZD1897 exhibits anticancer activity and synergistically inhibits the activity of acute myeloid leukemia (AML) cells in combination with Capivasertib (HY-15431). This synergistic inhibitory effect is achieved through the inhibition of the mTOR and MCL1 pathways .
    AZD1897
  • HY-15431A
    (R)-Capivasertib

    (R)-AZD5363

    		 Akt Cancer
    (R)-Capivasertib ((R)-AZD5363) is the R-enantiomer of Capivasertib (HY-15431) .
    (R)-Capivasertib

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