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Results for "

CaSR agonist

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CaSR (20) Biochemical Assay Reagents (1) Calcium Channel (1) Isotope-Labeled Compounds (1) Reference Standards (1)
By Research Areas:	Cancer (3) Endocrinology (4) Metabolic Disease (8) Neurological Disease (6)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: CaSR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-117851

AC-265347	CaSR	Metabolic Disease Endocrinology
AC-265347 is a calcium-sensing receptor (CaSR) agonist and positive allosteric modulator (ago-PAM) with the functional affinity (pK_B) of 5.1. AC-265347 can be used for the research of hyperparathyroidism and related diseases .

HY-107773

GSK3004774	CaSR	Metabolic Disease
GSK3004774 is a potent, nonabsorbable agonist of *CaSR, with an pEC₅₀* of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC₅₀ of 50 nM for human CaSR .

HY-P4376A

Gamma-Glu-Abu TFA	CaSR	Neurological Disease
Gamma-Glu-Abu TFA is the TFA salt form of Gamma-Glu-Abu (HY-P4376). Gamma-Glu-Abu TFA is an agonist for calcium sensing receptor (CaSR), that activates the *CaSR* with an EC₅₀ of 0.21 μM in HEK-293 cell .

HY-121584

Lycoperodine-1 Cyclomethyltryptophan	CaSR	Metabolic Disease
Lycoperodine-1 (Cyclomethyltryptophan) is an active product that can be isolated from tomato fruits (Lycopersicon sculentum). Lycoperodine-1 act as an agonist of Ca ²⁺ sensing receptors (CaSR) .

HY-139201B

Poly-D-lysine hydrobromide (MW 84000) PDLHB (MW 84000)	CaSR	Neurological Disease Cancer
Poly-D-lysine hydrobromide (MW 84000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a *CaSR* agonist peptide .

HY-17613

Evocalcet 3 Publications Verification KHK7580	CaSR	Metabolic Disease
Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .

HY-P4376

Gamma-Glu-Abu	CaSR	Neurological Disease
Gamma-Glu-Abu is an agonist for calcium sensing receptor (CaSR), that activates the *CaSR* with an EC₅₀ of 0.21 μM in HEK-293 cell .

HY-P11200

γ-Glu-Asn γ-Glutamylasparagine	Calcium Channel	Neurological Disease
γ-Glu-Asn (γ-Glutamylasparagine) is a calcium sensing receptor (CaSR) agonist. γ-Glu-Asn is a dipeptide composed of glutamic acid and asparagine .

HY-139201H

Poly-D-lysine hydrobromide (MW ≥300000) PDLHB (MW ≥300000)	CaSR	Others
Poly-D-lysine hydrobromide (PDLHB) (MW ≥300000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201E

Poly-D-lysine hydrobromide (MW 150000-300000) PDLHB (MW 150000-300000)	CaSR	Others
Poly-D-lysine hydrobromide (PDLHB) (MW 150000-300000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201C

Poly-D-lysine hydrobromide (MW 1000-5000) PDLHB (MW 1000-5000)	CaSR	Others
Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201A

Poly-D-lysine hydrobromide (MW 70000-150000) PDLHB (MW 70000-150000)	Biochemical Assay Reagents CaSR	Neurological Disease Cancer
Poly-D-lysine hydrobromide (MW 70000-150000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a *CaSR* agonist peptide .

HY-139201D

Poly-D-lysine hydrobromide (MW 4000-15000) PDLHB (MW 4000-15000)	CaSR	Others
Poly-D-lysine hydrobromide (PDLHB) (MW 4000-15000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201

Poly-D-lysine hydrobromide (MW 30000-70000) PDLHB (MW 30000-70000)	CaSR	Neurological Disease Metabolic Disease Cancer
Poly-D-lysine hydrobromide (MW 30000-70000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a *CaSR* agonist peptide .

HY-W843885

H-Glu-Thr-OH L-α-Glutamyl-L-threonine	CaSR	Others
H-Glu-Thr-OH (L-α-Glutamyl-L-threonine) is a dipeptide made up of two amino acids—glutamic acid (Glu) and threonine (Thr)—connected by a peptide bond, and it acts as an agonist for the extracellular calcium-sensing receptor (CaSR) .

HY-17613R

Evocalcet (Standard) KHK7580 (Standard)	Reference Standards CaSR	Metabolic Disease
Evocalcet (Standard) is the analytical standard of Evocalcet. This product is intended for research and analytical applications. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .

HY-121584R

Lycoperodine-1 (Standard)	CaSR	Metabolic Disease
Lycoperodine-1 (Standard) is the analytical standard of Lycoperodine-1. This product is intended for research and analytical applications. Lycoperodine-1 (Cyclomethyltryptophan) is an active product that can be isolated from tomato fruits (Lycopersicon sculentum). Lycoperodine-1 act as an agonist of Ca2+ sensing receptors (CaSR) .

HY-17613S

Evocalcet-d4 KHK7580-d₄	Isotope-Labeled Compounds CaSR	Metabolic Disease
Evocalcet-d₄ (KHK7580-d₄) is deuterium labeled Evocalcet. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .

HY-109106A

Upacicalcet sodium SK-1403; AJT240; PLS240	CaSR	Endocrinology
Upacicalcet sodium is a non-peptide calcimimetic that acts as a *CaSR* agonist (EC₅₀ = 10.8 nM). Upacicalcet sodium reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet sodium is useful for studying SHPT .

HY-109106

Upacicalcet SK-1403 free acid; AJT240 free acid; PLS240 free acid	CaSR	Endocrinology
Upacicalcet is a non-peptide calcimimetic that acts as a *CaSR* agonist (EC₅₀ = 10.8 nM). Upacicalcet reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet is useful for studying SHPT .

HY-109106B

(Rac)-Upacicalcet (Rac)-SK-1403 free acid; (Rac)-AJT240 free acid; (Rac)-PLS240 free acid	CaSR	Endocrinology
(Rac)-Upacicalcet is the racemate of Upacicalcet (HY-109106). Upacicalcet is a non-peptide calcimimetic that acts as a *CaSR* agonist (EC₅₀ = 10.8 nM). Upacicalcet reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet is useful for studying SHPT .

Cat. No.	Product Name	Type

HY-139201H

Poly-D-lysine hydrobromide (MW ≥300000) PDLHB (MW ≥300000)	Cell Assay Reagents
Poly-D-lysine hydrobromide (PDLHB) (MW ≥300000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201E

Poly-D-lysine hydrobromide (MW 150000-300000) PDLHB (MW 150000-300000)	Cell Assay Reagents
Poly-D-lysine hydrobromide (PDLHB) (MW 150000-300000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201C

Poly-D-lysine hydrobromide (MW 1000-5000) PDLHB (MW 1000-5000)	Cell Assay Reagents
Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

HY-139201D

Poly-D-lysine hydrobromide (MW 4000-15000) PDLHB (MW 4000-15000)	Cell Assay Reagents
Poly-D-lysine hydrobromide (PDLHB) (MW 4000-15000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide is a CaSR agonist peptide .

Cat. No.	Product Name	Target	Research Area

HY-P4376A

Gamma-Glu-Abu TFA	CaSR	Neurological Disease
Gamma-Glu-Abu TFA is the TFA salt form of Gamma-Glu-Abu (HY-P4376). Gamma-Glu-Abu TFA is an agonist for calcium sensing receptor (CaSR), that activates the *CaSR* with an EC₅₀ of 0.21 μM in HEK-293 cell .

HY-W843885

H-Glu-Thr-OH L-α-Glutamyl-L-threonine	CaSR	Others
H-Glu-Thr-OH (L-α-Glutamyl-L-threonine) is a dipeptide made up of two amino acids—glutamic acid (Glu) and threonine (Thr)—connected by a peptide bond, and it acts as an agonist for the extracellular calcium-sensing receptor (CaSR) .

HY-P4376

Gamma-Glu-Abu	CaSR	Neurological Disease
Gamma-Glu-Abu is an agonist for calcium sensing receptor (CaSR), that activates the *CaSR* with an EC₅₀ of 0.21 μM in HEK-293 cell .

HY-P11200

γ-Glu-Asn γ-Glutamylasparagine	Calcium Channel	Neurological Disease
γ-Glu-Asn (γ-Glutamylasparagine) is a calcium sensing receptor (CaSR) agonist. γ-Glu-Asn is a dipeptide composed of glutamic acid and asparagine .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-121584

Lycoperodine-1 Cyclomethyltryptophan	Structural Classification Alkaloids Source classification Solanum lycopersicum L. Solanaceae Plants Indole Alkaloids	CaSR
Lycoperodine-1 (Cyclomethyltryptophan) is an active product that can be isolated from tomato fruits (Lycopersicon sculentum). Lycoperodine-1 act as an agonist of Ca ²⁺ sensing receptors (CaSR) .

HY-121584R

Lycoperodine-1 (Standard)	Structural Classification Alkaloids Source classification Solanum lycopersicum L. Solanaceae Plants Indole Alkaloids	CaSR
Lycoperodine-1 (Standard) is the analytical standard of Lycoperodine-1. This product is intended for research and analytical applications. Lycoperodine-1 (Cyclomethyltryptophan) is an active product that can be isolated from tomato fruits (Lycopersicon sculentum). Lycoperodine-1 act as an agonist of Ca2+ sensing receptors (CaSR) .

Cat. No.	Product Name	Chemical Structure

HY-17613S

Evocalcet-d4
Evocalcet-d₄ (KHK7580-d₄) is deuterium labeled Evocalcet. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .

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CaSR agonist

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products