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Results for "

CYP3A biomarker

" in MedChemExpress (MCE) Product Catalog:

3

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3

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Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-113327
    1,3,7-Trimethyluric acid

    		Endogenous Metabolite Cancer
    1,3,7-Trimethyluric acid is the metabolite of caffeine. The metabolic ratio 1,3,7-Trimethyluric acid to caffeine can be evaluated as a biomarker to describe variability in CYP3A activity in a cohort .
    1,3,7-Trimethyluric acid
  • HY-113482
    1β-Hydroxydeoxycholic acid

    1β-OH-DCA

    		 Endogenous Metabolite Cytochrome P450 Metabolic Disease
    1β-Hydroxydeoxycholic acid (1β-OH-DCA), a secondary bile acid, is a CYP3A biomarker. Deoxycholic acid is specifically metabolized into 1β-Hydroxydeoxycholic acid by CYP3A4 and CYP3A7 using recombinant human CYP450 enzymes .
    1β-Hydroxydeoxycholic acid
  • HY-113327R
    1,3,7-Trimethyluric acid (Standard)

    		Drug Metabolite Endogenous Metabolite Cancer
    Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
    1,3,7-Trimethyluric acid (Standard)

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