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CSBP ligands

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175430
    TNF-α-IN-26

    		TNF Receptor Inflammation/Immunology
    TNF-α-IN-26 (Compound 18) is a TNF-α inhibitor with an IC50 of 0.10  μM for CSBP ligands. TNF-α-IN-26 inhibits LPS (HY-D1056)-stimulated TNF production in mice model. TNF-α-IN-26 can be used for inflammatory diseases research .
    TNF-α-IN-26
  • HY-178214
    CSBP ligand 1

    		Ser/Thr Kinase Lipoxygenase Inflammation/Immunology
    CSBP ligand 1 (Compound 36) is a ligand of CSBP, with an IC50 of 0.08 μM for CSBP binding. CSBP ligand 1 can inhibit the production of TNF in mice treated with LPS (HY-D1056). CSBP ligand 1 has no significant inhibitory activity against PGHS-1 (IC50: 16 μM) and 5-LO (IC50: 60 μM). CSBP ligand 1 can be used in the research of inflammation-related diseases .
    CSBP ligand 1

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