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CPS 021

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-174247
    CPS-021

    		PROTACs PAK Cadherin Cancer
    CPS-021 is a selective PAK4 PROTAC degrader with a DC50 of 50 nM. CPS-021 has potent antimigratory and invasive activity and significantly suppresses the invasion and metastasis of tumor cells in A549-luc lung metastasis mice model . Pink: PAK4 ligand (HY-174822); Blue: CRBN ligase ligand (HY-10984); Black: linker
    CPS-021
  • HY-174248
    PS21M

    		PROTACs PAK Cancer
    PS21M is a negative control of CPS-021 (HY-174247). PS21M cannot effectively degrade PAK4 in MDA-MB-231 cells. (Pink: Target Protein Ligand (HY-174822); Black: Linker; Blue: E3 Ligase Ligand (HY-W586822)) .
    PS21M

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