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Results for "

COL 3

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Recombinant Proteins

2

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13648
    Incyclinide
    5+ Cited Publications

    CMT-3; COL-3

    		 MMP Cancer
    Incyclinide (CMT-3, COL-3) is a matrix metalloproteinase (MMP) inhibitor and inhibiting angiogenesis, tumor growth and invasion, and metastasis.
    Incyclinide
  • HY-120006A
    (rel)-AR234960
    1 Publications Verification

    		 ERK Cardiovascular Disease
    (rel)-AR234960 is a selective and competitive agonist of the G protein-coupled receptor MAS. (rel)-AR234960 binds to the MAS receptor to activate the downstream ERK1/2 signaling pathway, inducing the expression of connective tissue growth factor (CTGF) and its downstream collagen subtype genes (such as COL1A1, COL3A1). (rel)-AR234960 promotes collagen synthesis in cardiac fibroblasts through the MAS-ERK1/2-CTGF pathway and aggravates extracellular matrix remodeling. (rel)-AR234960's in vitro effect can be blocked by the MAS inverse agonist AR244555 and MEK1 inhibitor. (rel)-AR234960 regulates the expression of cardiac fibrosis-related genes and can be used in the study of heart failure .
    (rel)-AR234960
  • HY-RS24184
    Col3a1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Col3a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Col3a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Col3a1 Rat Pre-designed siRNA Set A
    Col3a1 Rat Pre-designed siRNA Set A
  • HY-RS17719
    Col3a1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Col3a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Col3a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Col3a1 Mouse Pre-designed siRNA Set A
    Col3a1 Mouse Pre-designed siRNA Set A
  • HY-RS02982
    COL3A1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    COL3A1 Human Pre-designed siRNA Set A contains three designed siRNAs for COL3A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    COL3A1 Human Pre-designed siRNA Set A
    COL3A1 Human Pre-designed siRNA Set A
  • HY-172258
    5-HT2B antagonist-2

    		5-HT Receptor Cancer
    5-HT2B antagonist-2 (Compound 19c) is a 5HT2B receptor antagonist with an IC50 of 1.09 nM. 5-HT2B antagonist-2 can downregulate the expression of fibrosis-related genes α-SMA, Timp1, Col1a1, and Col3a1, and significantly reduce the deposition of fibrosis, thereby reducing the fibrotic area and inhibiting the fibrotic process in CCl4-induced liver fibrosis mouse models. 5-HT2B antagonist-2 can be used in the study of immune inflammatory-related diseases, particularly in the research of pulmonary fibrosis diseases .
    5-HT2B antagonist-2

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