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CMKLR1 antagonist 3

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-174140
    CMKLR1 antagonist 3

    		Chemerin Receptor Metabolic Disease Inflammation/Immunology
    CMKLR1 antagonist 3 (Compound VU0514009) is a competitive chemokine-like receptor 1 (CMKLR1) antagonist (EC50=2 nM). CMKLR1 antagonist 3 prevents chemerin-9-induced arrestin recruitment and receptor internalization, significantly reducing Ca 2+ flux response in HEK293 cells. CMKLR1 antagonist 3 is promising for research of inflammatory diseases and metabolic syndrome .
    CMKLR1 antagonist 3

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