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Results for "

CHAC1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

2

Natural
Products

2

Recombinant Proteins

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6929
    Angelic acid

    		Others Neurological Disease Cancer
    Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity [1] .
    Angelic acid
  • HY-RS02590
    CHAC1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CHAC1 Human Pre-designed siRNA Set A contains three designed siRNAs for CHAC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CHAC1 Human Pre-designed siRNA Set A
    CHAC1 Human Pre-designed siRNA Set A
  • HY-RS20883
    Chac1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Chac1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Chac1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Chac1 Mouse Pre-designed siRNA Set A
    Chac1 Mouse Pre-designed siRNA Set A
  • HY-RS27400
    Chac1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Chac1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Chac1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Chac1 Rat Pre-designed siRNA Set A
    Chac1 Rat Pre-designed siRNA Set A
  • HY-N6929R
    Angelic acid (Standard)

    		Reference Standards Others Neurological Disease Cancer
    Angelic acid (Standard)) is the analytical standard of Angelic acid (HY-N6929). This product is intended for research and analytical applications. Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity [1] .
    Angelic acid (Standard)
  • HY-P2060
    CGP 44099

    		Renin Cardiovascular Disease
    CGP 44099 is a renin inhibitor. CGP 44099 can be used to study the ischemic injury and reperfusion arrhythmias in rat hearts [1].
    CGP 44099

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