2. Search Result
Search Result
Results for "

CFT8634

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145925B
    CFT8634

    		PROTACs Epigenetic Reader Domain Cancer
    CFT8634 is an orally bioavailable PROTAC BRD9 targeted degrader based on the E3 ubiquitin ligase CRBN mechanism. CFT8634 can be used for the study of synovial sarcoma and SMARCB1-deficient solid tumors (Pink: BRD9 ligand (HY-169988); Blue: E3 ligase ligand (HY-169989); Black: linker (HY-169991). CFT8634 is a heterobifunctional molecule that binds to BRD9 at one end and recruits CRBN at the other end, which can inhibit the growth of tumor cells that depend on BRD9. CFT8634 can be used for the study of SMARCB1-related cancers (such as synovial sarcoma and malignant rhabdoid tumor) .
    CFT8634
  • HY-145925C
    (S,R)-CFT8634

    		PROTACs Epigenetic Reader Domain Cancer
    (S,R)-CFT8634 (compound 176) is a selective and orally active PROTAC-class BRD9 protein degrader. (S,R)-CFT8634 has the potential to study BRD9-mediated diseases, including but not limited to abnormal cell proliferation. (S,R)-CFT8634 consists of a target protein ligand (red part) BRD9 ligand-5 (HY-169988), an E3 ligase ligand (blue part) CRBN ligand-11 (HY-169989), and a PROTAC linker (black part) 1-(3,3-Difluoro-4-piperidinyl)piperazine (HY-169991). E3 ligase ligand and linker can form E3 Ligase Ligand-linker Conjugate 142 (HY-169990) .
    (S,R)-CFT8634
  • HY-169991
    1-(3,3-Difluoro-4-piperidinyl)piperazine

    		PROTAC Linkers Others
    1-(3,3-Difluoro-4-piperidinyl)piperazine is the PROTAC linker of CFT8634 (HY-145925B) and can be used in the synthesis of PROTACs .
    1-(3,3-Difluoro-4-piperidinyl)piperazine
  • HY-169990
    E3 Ligase Ligand-linker Conjugate 142

    		E3 Ligase Ligand-Linker Conjugates Cancer
    E3 Ligase Ligand-linker Conjugate 142 is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of CFT8634 (HY-145925B) .
    E3 Ligase Ligand-linker Conjugate 142
  • HY-169989
    CRBN ligand-11

    		Ligands for E3 Ligase Cancer
    CRBN ligand-11 is the E3 ubiquitin ligase ligand for CFT8634 (HY-145925B). CRBN ligand-11 can be used for the synthesis of PROTACs .
    CRBN ligand-11
  • HY-169988
    BRD9 ligand-5

    		Ligands for Target Protein for PROTAC Cancer
    BRD9 ligand-5 (Compound 172-11) is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). BRD9 ligand-5 can be utilized for the synthesis of CFT8634 (HY-145925B) .
    BRD9 ligand-5

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: