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CDK4/6/HDAC-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-170651
    CDK4/6/HDAC-IN-1

    		CDK HDAC Apoptosis Cancer
    CDK4/6/HDAC-IN-1 (Compound N14) is a dual-targeting inhibitor of CDK4/6 and HDAC (IC50: CDK4 = 7.23 nM, CDK6 = 13.20 nM, HDAC1 = 55.66 nM, HDAC6 = 48.38 nM). CDK4/6/HDAC-IN-1 induces cell Apoptosis and G0/G1 phase arrest through HDAC-p21-CDK signaling pathway. CDK4/6/HDAC-IN-1 inhibits hepatocellular carcinoma [1].
    CDK4/6/HDAC-IN-1

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