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Results for "

CBZ

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (9) Amino Acid Derivatives (9) Amyloid-β (1) Apoptosis (1) Autophagy (5) Beta-lactamase (3) Biochemical Assay Reagents (22) Calcium Channel (2) Caspase (1) Cathepsin (2) Cholinesterase (ChE) (1) COX (1) Drug Derivative (2) Drug Intermediate (3) Drug Isomer (1) Drug-Linker Conjugates for ADC (2) Factor Xa (1) Fluorescent Dye (4) Glutaminase (1) HDAC (2) HSV (1) Isotope-Labeled Compounds (6) Kallikrein (1) Liposome (1) Lipoxygenase (1) LYTACs (1) Microtubule/Tubulin (1) Mitophagy (5) MMP (1) mTOR (1) Potassium Channel (2) PROTAC Linkers (31) PROTACs (2) Reference Standards (2) Ser/Thr Protease (1) Sodium Channel (5) Stearoyl-CoA Desaturase (SCD) (2) Thrombin (1)
By Research Areas:	Cancer (54) Cardiovascular Disease (2) Infection (4) Inflammation/Immunology (3) Neurological Disease (11)
Click Chemistry:	Azide (2)

105

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0246

Carbamazepine Maximum Cited Publications 13 Publications Verification CBZ; NSC 169864	Sodium Channel Autophagy Mitophagy Potassium Channel Calcium Channel HDAC	Neurological Disease Cancer
Carbamazepine is an orally active pressure-sensitive sodium ion channel blocker with an IC₅₀ of 131 μM. Carbamazepine blocks voltage gated Na ⁺, Ca ²⁺, and K ⁺ channels, and is also a HDAC inhibitor (IC₅₀: 2 μM). Carbamazepine is an anticonvulsant and can be used for research of epilepsy and neuropathic pain .

HY-136626

Z-Ala-Ala-Asn-AMC 3 Publications Verification CBZ-Ala-Ala-Asn-AMC	Fluorescent Dye	Cancer
Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC .

HY-W103577

*1-(Cbz-amino)cyclopentanecarboxylic acid* CBZ-cycloleucine	Biochemical Assay Reagents	Others
1-(Cbz-amino)cyclopentanecarboxylic acid (Cbz-cycloleucine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W013905

Cbz-D-Valine	Amino Acid Derivatives	Others
Cbz-D-Valine is a valine derivative .

HY-P10198

Cbz-Lys-Lys-PABA-AMC diTFA	Fluorescent Dye	Others
Cbz-Lys-Lys-PABA-AMC diTFA is a fluorogenic peptide .

HY-160255

*N-Cbz-L-Cysteine* CBZ-cysteine	Beta-lactamase	Infection
N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) is a potent β-lactamase II inhibitor with a K_i value of 97 µM .

HY-160255A

*N-Cbz-D-Cysteine* CBZ-D-Cys	Beta-lactamase	Infection
N-Cbz-D-Cysteine (Cbz-D-Cys) (compound 5) is a potent β-lactamase II inhibitor with a K_i value of 20.1 µM .

HY-78897

CBZ-L-Isoleucine	Amino Acid Derivatives	Others
CBZ-L-Isoleucine is an isoleucine derivative .

HY-I1061

Cbz-L-Alloisoleucine	Amino Acid Derivatives	Others
Cbz-L-Alloisoleucine is an isoleucine derivative .

HY-126375R

Cbz-?Valaciclovir (Standard) Benzyloxycarbonyl valacyclovir (Standard)	Drug Intermediate Reference Standards	Infection
Cbz-Valaciclovir (Standard) is the analytical standard of Cbz-Valaciclovir. This product is intended for research and analytical applications. Cbz-Valaciclovir (Benzyloxycarbonyl valacyclovir) can be used to prepare Valaciclovir (HY-17425) and for antiviral research .

HY-P5027

Cbz-Lys-Arg-pNA	Ser/Thr Protease Kallikrein Factor Xa Thrombin	Cardiovascular Disease
Cbz-Lys-Arg-pNA is a peptide substrate containing pNA as the chromogenic group. Cbz-Lys-Arg-pNA is widely used in enzymatic analysis, including thrombin, plasmin, factor Xa and Kallikrein .

HY-W009503

Cbz-L-Aspartic anhydride	Amino Acid Derivatives	Others
Cbz-L-Aspartic anhydride is an aspartic acid derivative .

HY-150242A

Cbz-Ala-Ala-Asn TFA	Liposome	Others
Cbz-Ala-Ala-Asn TFA is a peptide that designed based on the sequence of the substrate of legumain. Legumain is a cysteine protease. Cbz-Ala-Ala-Asn TFA can be applied as a scaffold for drug delivery .

HY-400312

Cbz-D-Leu-Val-Boc	Biochemical Assay Reagents	Cancer
Cbz-D-Leu-Val-Boc is a peptide derivative.

HY-114267

Cbz-B3A	mTOR	Others
Cbz-B3A is a potent and selective inhibitor of mTORC1 signaling that appear to bind to ubiquilins 1, 2, and 4, and Cbz-B3A inhibits the phosphorylation of eIF4E-binding protein 1 (4EBP1).

HY-172292

Cbz-GGFG-Bn	Biochemical Assay Reagents	Others
Cbz-GGFG-Bn is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W009121

Cbz-D-Trp-OH	Stearoyl-CoA Desaturase (SCD)	Inflammation/Immunology Cancer
Cbz-D-Trp-OH is a competitive inhibitor of SCD, with IC₅₀ of 86 μM and K_i of 71 μM .

HY-126375

Cbz-Valaciclovir Benzyloxycarbonyl valacyclovir	Drug Intermediate HSV	Infection
Cbz-Valaciclovir (Benzyloxycarbonyl valacyclovir) can be used to prepare Valaciclovir (HY-17425) and for antiviral research .

HY-W011197

Cbz-L-Trp-OH	Stearoyl-CoA Desaturase (SCD)	Inflammation/Immunology Cancer
Cbz-L-Trp-OH is a competitive inhibitor of SCD, with an IC₅₀ of 2.5 μM and a K_i of 2.1 μM .

HY-44312

Cbz-TRIS tri-acid	Biochemical Assay Reagents	Others
Cbz-TRIS tri-acid is a small molecule compound containing several functional groups, including a carbamate group, a tris group, and three carboxylic acid groups.

HY-140490

Cbz-N-PEG10-acid	PROTAC Linkers	Cancer
Cbz-N-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-143832

Cbz-PEG5-Br	PROTAC Linkers	Cancer
Cbz-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W190968

Cbz-PEG2-bromide	PROTAC Linkers	Cancer
Cbz-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140443

Cbz-aminooxy-PEG8-acid	PROTAC Linkers	Cancer
Cbz-aminooxy-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W095029

Cbz-Gly-Pro-OH	Biochemical Assay Reagents	Others
Cbz-Gly-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W011750

Z-Pyr-OH CBZ-L-pyroglutamic acid	Biochemical Assay Reagents	Others
Z-Pyr-OH (Cbz-L-pyroglutamic acid) can be used as a biochemical assay reagent .

HY-159617

Cbz-Pip-2C-Pip-C-Pip	PROTAC Linkers	Cancer
Cbz-Pip-2C-Pip-C-Pip is a PROTAC linker. Cbz-Pip-2C-Pip-C-Pip can be used for synthesis PROTAC Cbl-b-IN-1 (HY-159608) .

HY-163382

Cbz-Gly-Pro-Ala-O-cinnamyl	Beta-lactamase Cholinesterase (ChE) Amyloid-β	Neurological Disease
Cbz-Gly-Pro-Ala-O-cinnamyl (compound 25) is a small peptide targeting BACE-1 and AChE with the IC₅₀ values of 0.02 μM and 1 μM, respectively. Cbz-Gly-Pro-Ala-O-cinnamyl shows neuroprotective effect and can be used for study of Alzheimer’s disease .

HY-140491

Cbz-N-amido-PEG20-acid	PROTAC Linkers	Cancer
Cbz-N-amido-PEG20-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140238

Cbz-N-PEG15-amine	PROTAC Linkers	Cancer
Cbz-N-PEG15-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140444

Cbz-aminooxy-PEG8-Boc	PROTAC Linkers	Cancer
Cbz-aminooxy-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-129352

Cbz-Phe-(Alloc)Lys-PAB-PNP	ADC Linker	Cancer
Cbz-Phe-(Alloc)Lys-PAB-PNP is an cleavable linker for antibody-drug conjugates (ADC) design.

HY-W009033

Cbz-Lys(Boc)-OH	Biochemical Assay Reagents Amino Acid Derivatives	Others
Cbz-Lys(Boc)-OH is a protected amino acid, primarily utilized in peptide synthesis, protein engineering, and drug development, particularly in research involving lysine residues .

HY-172790

Cbz-(S,S)-Pro-Pro-allyl	COX Lipoxygenase	Inflammation/Immunology
Cbz-(S,S)-Pro-Pro-allyl (compound 1a) is a dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase with IC₅₀ values of 0.146 nM, 0.003 nM, 0.64 nM for COX-1, COX-2, 5-LOX, respectively. Cbz-(S,S)-Pro-Pro-allyl has anti-inflammatory activity .

HY-47812

Cbz-D-Glu(Bn)-Gly-Gly-Gly-Gly	ADC Linker	Cancer
Cbz-(D-Glu)Bn-Gly-Gly-Gly-Gly is a cleavable ADC linker.

HY-133358

Cbz-NH-PEG12-C2-acid	PROTAC Linkers	Cancer
Cbz-NH-PEG12-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140489

Cbz-NH-PEG5-C2-acid	PROTAC Linkers	Cancer
Cbz-NH-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W019796

Cbz-NH-PEG4-C2-acid	PROTAC Linkers	Cancer
Cbz-NH-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-133359

Cbz-NH-PEG24-C2-acid	PROTAC Linkers	Cancer
Cbz-NH-PEG24-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140488

Cbz-NH-PEG3-C2-acid	PROTAC Linkers	Cancer
Cbz-NH-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-133360

Cbz-NH-PEG36-C2-acid	PROTAC Linkers	Cancer
Cbz-NH-PEG36-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-130192

Cbz-NH-PEG8-C2-acid	PROTAC Linkers	Cancer
Cbz-NH-PEG8-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-130443

Cbz-NH-PEG6-C2-acid	PROTAC Linkers	Cancer
Cbz-NH-PEG6-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140487

Cbz-NH-PEG2-C2-acid	PROTAC Linkers	Cancer
Cbz-NH-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-135923

Cbz-NH-PEG2-CH2COOH	PROTAC Linkers	Cancer
Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-135942

Cbz-NH-PEG8-CH2COOH	PROTAC Linkers	Cancer
Cbz-NH-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-135925

Cbz-NH-PEG1-CH2COOH	PROTAC Linkers	Cancer
Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-135919

Cbz-NH-PEG5-CH2COOH	PROTAC Linkers	Cancer
Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-133357

Cbz-NH-PEG10-CH2COOH	PROTAC Linkers	Cancer
Cbz-NH-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-135913

Cbz-NH-PEG3-CH2COOH	PROTAC Linkers	Cancer
Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Cat. No.	Product Name	Target	Research Area

HY-136626

Z-Ala-Ala-Asn-AMC 3 Publications Verification CBZ-Ala-Ala-Asn-AMC	Fluorescent Dye	Cancer
Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC .

HY-W013905

Cbz-D-Valine	Amino Acid Derivatives	Others
Cbz-D-Valine is a valine derivative .

HY-P10213

CbZ-Ala-Ala-Ala-Ala	Peptides	Others
CbZ-Ala-Ala-Ala-Ala is a modified peptide .

HY-P10198

Cbz-Lys-Lys-PABA-AMC diTFA	Fluorescent Dye	Others
Cbz-Lys-Lys-PABA-AMC diTFA is a fluorogenic peptide .

HY-78897

CBZ-L-Isoleucine	Amino Acid Derivatives	Others
CBZ-L-Isoleucine is an isoleucine derivative .

HY-I1061

Cbz-L-Alloisoleucine	Amino Acid Derivatives	Others
Cbz-L-Alloisoleucine is an isoleucine derivative .

HY-P5027

Cbz-Lys-Arg-pNA	Ser/Thr Protease Kallikrein Factor Xa Thrombin	Cardiovascular Disease
Cbz-Lys-Arg-pNA is a peptide substrate containing pNA as the chromogenic group. Cbz-Lys-Arg-pNA is widely used in enzymatic analysis, including thrombin, plasmin, factor Xa and Kallikrein .

HY-W009503

Cbz-L-Aspartic anhydride	Amino Acid Derivatives	Others
Cbz-L-Aspartic anhydride is an aspartic acid derivative .

HY-400312

Cbz-D-Leu-Val-Boc	Biochemical Assay Reagents	Cancer
Cbz-D-Leu-Val-Boc is a peptide derivative.

HY-P5040

Cbz-Pro-Leu-Gly-OH	Peptides	Neurological Disease
Cbz-Pro-Leu-Gly-OH is a tripeptide that can be used in Parkinson's disease research .

HY-W011750

Z-Pyr-OH CBZ-L-pyroglutamic acid	Biochemical Assay Reagents	Others
Z-Pyr-OH (Cbz-L-pyroglutamic acid) can be used as a biochemical assay reagent .

HY-P5008

Cbz-Asn-Gly-OH	Peptides	Others
Cbz-Asn-Gly-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5042

Cbz-Tyr-Ala-OH	Peptides	Others
Cbz-Tyr-Ala-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5024

Cbz-Ile-Pro-OH NSC 333754	Peptides	Others
Cbz-Ile-Pro-OH (NSC 333754) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5012

Cbz-Glu-Gly-OH NSC 186902	Peptides	Others
Cbz-Glu-Gly-OH (NSC 186902) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-134113

Z-Gly-Pro-Arg-pNA CBZ-Chromozym TH	Peptides	Others
Z-Gly-Pro-Arg-pNA (z-GPR-pNA) is a photometric substrate in Prostate-Specific Antigen (PSA) activation protease assays. Z-Gly-Pro-Arg-pNA (z-GPR-pNA) can be used for the test of trypsin activity .

HY-P1759

*N-CBZ-Phe-Arg-AMC* Z-FR-AMC	Cathepsin	Others
N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes .

HY-76317

Z-DL-Pro-OH N-CBZ-DL-proline; DL-CBZ-Proline	Amino Acid Derivatives	Others
Z-DL-Pro-OH (N-Cbz-DL-proline) is a proline derivative, can be used for the synthesis of agents or other compounds .

HY-75332

Z-D-Phg-OH D-CBZ phenylglycine	Amino Acid Derivatives	Others
Z-D-Phg-OH (D-Cbz phenylglycine) is a N-blocked amino acids with K_d values of 390 μM and 323 μM for tBuCQN and tBuCQD, respectively .

HY-P1759B

*N-CBZ-Phe-Arg-AMC TFA* Z-FR-AMC TFA	Cathepsin	Others
N-CBZ-Phe-Arg-AMC (Z-FR-AMC) TFA is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes .

HY-P1010

Z-LEHD-FMK 10+ Cited Publications	Caspase Apoptosis	Neurological Disease Cancer
Z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9, protects against lethal reperfusion injury and attenuates apoptosis. Z-LEHD-FMK exhibits the neuroprotective effect in a rat model of spinal cord trauma .

HY-P2269

MAIT-203	Drug Derivative	Cancer
MAIT-203, a cyclopentyalanin-derived peptidomimetic, potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. MAIT-203 binds APC-ARM with a K_i of 0.015 μM and a K_d of 0.036 μM. MAIT-203 significantly represses the migration and invasion of colorectal cancer cells.

HY-P2269A

MAIT-203 acetate	Drug Derivative	Cancer
MAIT-203 acetate is a cyclopentyalanin-derived peptidomimetic, potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. MAIT-203 acetate binds APC-ARM with a K_i value of 0.015 μM and aK_d value of 0.036 μM. MAIT-203 acetate significantly represses the migration and invasion of colorectal cancer cells .

HY-W003991

*N-Benzyl-N-Cbz-glycine*	Amino Acid Derivatives	Others
2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid is a Glycine (HY-Y0966) derivative .

HY-W060779

*(4R)-1-Cbz-4-hydroxy-D-proline methyl ester*	Amino Acid Derivatives	Others
1-Benzyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate is a proline derivative .

HY-P3106

(Z-Ala-Ala-Ala-Ala)2Rh110 (Z-Ala-Ala-Ala-Ala)2Rhodamine110; bis-CBZ-L-alanyl-L-arginine amide Rhodamine 110	Fluorescent Dye	Others
(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.

Cat. No.	Product Name	Chemical Structure

HY-B0246S

Carbamazepine-d10
Carbamazepine-d₁₀ is the deuterium labeled Carbamazepine. Carbamazepine (CBZ), a sodium channel blocker, is an anticonvulsant agent .

HY-B0246S2

Carbamazepine-d8
Carbamazepine-d₈ is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent, with an IC₅₀ of 131 μM .

HY-W653882

Carbamazepine-d2,15N
Carbamazepine-d2,15N is a deuterated labeled Carbamazepine-d2,15N .

HY-B0246S3

Carbamazepine-(Ph)d8
Carbamazepine-(Ph)d8 (CBZ-(Ph)d8; NSC 169864-(Ph)d8) is the deuterium labeled Carbamazepine-(Ph) (HY-B0246) .

HY-B0246S4

Carbamazepine-d4
Carbamazepine-d4 (CBZ-d4; NSC 169864-d4) is the deuterium labeled Carbamazepine-d4 (HY-B0246S4) .

HY-B0246S1

Carbamazepine-d2
Carbamazepine-d₂ is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent.

HY-W777099

*N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly[13C2,15N]-OBzl*
N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly[ ¹³C₂, ¹⁵N]-OBzl is the ¹³C- and ¹⁵N-labeled N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl.

Cat. No.	Product Name		Classification

HY-173261

Tri-GalNAc(OAc)3-Cbz		Azide
Tri-GalNAc(OAc)3-Cbz is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-159608

PROTAC Cbl-b-IN-1		Azide
PROTAC Cbl-b-IN-1 (compound 64) is a PROTAC targeting Cbl-b. PROTAC Cbl-b-IN-1 is composed of PROTAC target protein ligand Cbl-b-IN-21 (HY-159615), PROTAC Linker Cbz-Pip-2C-Pip-C-Pip (HY-159617) and E3 ubiquitin ligase ligand (3S) Lenalidomide-5-Br (HY-W797329), where the E3 ubiquitin ligase ligand + Linker conjugate is (3S) Lenalidomide-5-Pip-C-Pip-2C-Pip (HY-159618) ^{[1] ^.}

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