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C-286

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111573
    KCL-286

    C286

    		 RAR/RXR Others Neurological Disease Inflammation/Immunology
    KCL-286 (C286) is an orally active and brain-penetrant retinoic acid receptor (RAR) β2 agonist (EC50 = 1.9 nM). KCL-286 targets RARβ2 with good selectivity over RAR α (EC50 = 26 nM) and RAR γ (EC50 = 11 nM). KCL-286 activates RARβ2 in the injured neurons. KCL-286 induces axonal regeneration of both spinal and sensory nerves through the inhibitory environment of the CNS, modulates neuroinflammation and extracellular matrix molecules. KCL-286 can modulate the expression of CSPGs by neuronal secretion of decorin which promotes myelination and aids axonal growth. KCL-286 can be studied in research for area such as spinal cord injury and traumatic nerve injury .
    KCL-286
  • HY-CE00045A
    (10Z,13Z,16Z,19Z,22Z,25Z)-Octacosahexaenoyl-CoA

    C28:6(Omega-3)-CoA

    		 Biochemical Assay Reagents Others
    (10Z,13Z,16Z,19Z,22Z,25Z)-Octacosahexaenoyl-CoA (C28:6(Omega-3)-CoA) is an unsaturated fatty acyl-CoA.
    (10Z,13Z,16Z,19Z,22Z,25Z)-Octacosahexaenoyl-CoA

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