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Results for "

Brain cholinergic system

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W987949
    Z-4105

    		Others Neurological Disease
    Z-4105 (formula l) is a nootropic agent. Z-4105 restores the amnesic effect of electroconvulsive ehock (ECS) and methylazoxymethanol acetate (MAM), improving learning and memory function. Z-4105 increases the activity of the brain cholinergic system without affecting other neurotransmitter systems. Z-4105 significantly attenuates the neuropathic pain induced by chronic constrictive lesion (CCl) in the sciatic nerve of rat hind leg models and in the ligament of rat spinal nerve models. Z-4105 can be used for neuropathic pain and cerebral dysfunctional disorders research .
    Z-4105
  • HY-19085
    KW-6055

    		Cholinesterase (ChE) Neurological Disease
    KW-6055 is a benzylpyridine derivative with anti-amnesic effects. KW-6055 can increase the level of ACh in the brain cholinergic system and stimulate cholinergic neurons.
    KW-6055
  • HY-123934
    VU6007477

    		P-glycoprotein Neurological Disease
    VU6007477 is a brain-penetrant, selective M1 positive allosteric modulator (PAM) with an EC50 value of 230 nM. VU6007477 is also a human P-glycoprotein (P-gp) substrate with moderate permeability. VU6007477 displays improved central nervous system (CNS) penetration over the hydroxylated congeners. VU6007477 a pyranyl amide derivative, which is promising for research of robust cholinergic seizure activity .
    VU6007477

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