Search Result

Results for "

Ba-L

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (2) Antibiotic (3) Bacterial (4) CCR (5) Checkpoint Kinase (Chk) (2) CTLA-4 (2) CXCR (1) Cytochrome P450 (3) Drug-Linker Conjugates for ADC (1) Fungal (4) HIV (4) Interleukin Related (1) Microtubule/Tubulin (3) Mitochondrial Metabolism (1) Neurokinin Receptor (1) NOD-like Receptor (NLR) (1) PD-1/PD-L1 (2) Reference Standards (1) Small Interfering RNA (siRNA) (7) TNF Receptor (2)
By Research Areas:	Cancer (6) Endocrinology (1) Infection (12) Inflammation/Immunology (6)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (3) Human Pre-designed siRNA Sets (3) siRNAs (7)

Inhibitors & Agonists

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-162333

BAL-0028	NOD-like Receptor (NLR) Interleukin Related	Inflammation/Immunology
BAL-0028 is a reversible inhibitor of NLRP3 activation with an IC₅₀ value of 25 nM. BAL-0028 binds closely to the NACHT domain of the NLRP3 with K_D values of 104-123 nM. BAL-0028 can inhibit the secretion of IL-1β and has anti-inflammatory activity .

HY-14273

Isavuconazole 4 Publications Verification BaL-4815; RO-0094815	Fungal Cytochrome P450 Antibiotic	Infection Cancer
Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.

HY-100373

Isavuconazonium sulfate 2 Publications Verification BaL8557-002	Fungal	Infection
Isavuconazonium sulfate (BAL8557-002) is an orally active broad-spectrum antifungal molecule. Isavuconazonium sulfate is a precursor of the triazole antifungal active molecule Isavuconazole. Isavuconazonium sulfate can be used in the study of invasive aspergillosis, mucormycosis, blastomycosis, and Acanthamoeba keratitis .

HY-19916A

Lisavanbulin dihydrochloride BaL-101553 dihydrochloride	Microtubule/Tubulin TNF Receptor CTLA-4 PD-1/PD-L1 Checkpoint Kinase (Chk)	Cancer
Lisavanbulin (BAL-101553) dihydrochloride is the prodrug of the microtubule targeting agent Avanbulin (BAL 27862) (HY-106008). Lisavanbulin dihydrochloride exhibits antitumor activity, especially in tumors that express high levels of end-binding protein 1. Lisavanbulin dihydrochloride has ability to target tumor cell proliferation and affects the tumor microenvironment by reducing tumor microvasculature. Lisavanbulin dihydrochloride is also a spindle assembly checkpoint activator, agonistic anti-CD40 antibody, and double immune checkpoint blockade (anti-PD-1 and anti-CTLA-4). Lisavanbulin dihydrochloride induces cell cycle arrest and subsequent death or aberrant chromosome segregation. Lisavanbulin dihydrochloride can be studied in research for diffuse large B cell lymphoma (DLBCL) and glioblastoma .

HY-19916

Lisavanbulin BaL-101553	Microtubule/Tubulin Checkpoint Kinase (Chk) TNF Receptor PD-1/PD-L1 CTLA-4	Cancer
Lisavanbulin (BAL-101553) is the prodrug of the microtubule targeting agent Avanbulin (BAL 27862) (HY-106008). Lisavanbulin is a BBB-penetrant and orally active antitumor agent, especially in tumors that express high levels of end-binding protein 1. Lisavanbulin has ability to target tumor cell proliferation and affects the tumor microenvironment by reducing tumor microvasculature. Lisavanbulin is also a spindle assembly checkpoint activator, agonistic anti-CD40 antibody, and double immune checkpoint blockade (anti-PD-1 and anti-CTLA-4). Lisavanbulin induces cell cycle arrest and subsequent death or aberrant chromosome segregation. Lisavanbulin can be studied in research for diffuse large B cell lymphoma (DLBCL) and glioblastoma .

HY-14273R

Isavuconazole (Standard) BaL-4815 (Standard); RO-0094815 (Standard)	Reference Standards Fungal Cytochrome P450 Antibiotic	Infection
Isavuconazole (Standard) is the analytical standard of Isavuconazole. This product is intended for research and analytical applications. Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.

HY-14273S

Isavuconazole-d4 BaL-4815-d₄; RO-0094815-d₄	Fungal Cytochrome P450	Infection
Isavuconazole-d₄ is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi .

HY-106008

Avanbulin BaL27862	Microtubule/Tubulin	Cancer
Avanbulin (BAL27862) is a potent, Colchicine site-binding, tubulin assembly inhibitor. Avanbulin inhibits tubulin assembly at 37 °C with an IC₅₀ of 1.4 μM. Avanbulin binds to tubulin with an apparent K_d value of 244 nM. Avanbulin can be used for the research of cancer and cell division .

HY-19882

BAL-30072	Bacterial	Infection
BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC₉₀ values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively .

HY-106574

Ceftobiprole medocaril BaL5788	Bacterial	Infection Inflammation/Immunology
Ceftobiprole medocaril (BAL5788) is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .

HY-106574A

Ceftobiprole medocaril sodium BaL5788 sodium	Bacterial	Infection Inflammation/Immunology
Ceftobiprole medocaril (BAL5788) sodium is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .

HY-112579

Ceftobiprole 2 Publications Verification Ro 63-9141; BaL 9141	Bacterial Antibiotic	Infection Inflammation/Immunology
Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci with a MIC₉₀ value of 2 μg/mL for MRSA. Ceftobiprole also inhibits gram-positive and gram-negative pathogens. Ceftobiprole can be used for the study of hospital-acquired pneumonia (excluding ventilator-associated pneumonia) and community-acquired pneumonia .

HY-160408

*Mal-GGG-Bal-NHS ester*	ADC Linker	Cancer
Mal-GGG-Bal-NHS ester is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-B2078

Eprazinone	Neurokinin Receptor	Inflammation/Immunology
Eprazinone can enhance lung function and arterial oxygen levels and can be used in the study of chronic bronchitis. Higher doses of eprazinone increased phospholipid levels and decreased neutral lipid content in bronchoalveolar lavage (BAL) fluid, but had no effect on protein and cell levels in BAL. Eprazinone dose-dependently reduced short-circuit current (Isc), primarily by reducing chloride secretion at lower concentrations and affecting sodium and chloride transport at higher doses. Eprazinone may exert its anti-inflammatory effects by regulating BAL lipid composition and airway ion transport .

HY-RS17585

Dsg3 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Dsg3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dsg3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Dsg3 Mouse Pre-designed siRNA Set A Dsg3 Mouse Pre-designed siRNA Set A

HY-159927

TAK-661	CCR	Inflammation/Immunology
TAK-661 is a inhibitor of eosinophil chemotaxis. TAK-661 significantly reduces the bronchoconstriction during the late phase, along with the inhibition of eosinophilia in bronchoalveolar lavage (BAL) and the eosinophil infiltration into the airway wall .

HY-RS23564

Cel Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cel Rat Pre-designed siRNA Set A contains three designed siRNAs for Cel gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cel Rat Pre-designed siRNA Set A Cel Rat Pre-designed siRNA Set A

HY-164367

*Mal-Bal-Ph(β-D-Glucose)-7-MAD-MDCPT*	ADC Linker Drug-Linker Conjugates for ADC	Cancer
DBCO-PEG2-C2-acid is an ADC Linker. DBCO-PEG2-C2-acid can be used to synthesize Antibody-Drug Conjugates (ADCs) .

HY-17450A

Aplaviroc hydrochloride AK602 hydrochloride; GSK-873140 hydrochloride; GW-873140 hydrochloride	CCR HIV	Infection
Aplaviroc (AK 602) hydrochloride, a SDP derivative, is a CCR5 antagonist, with IC₅₀s of 0.1-0.4 nM for HIV-1_Ba-L, HIV-1_JRFL and HIV-1_MOKW.

HY-17450

Aplaviroc AK 602; GSK 873140; GW 873140	CCR HIV	Infection Endocrinology
Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist, with IC₅₀s of 0.1-0.4 nM for HIV-1_Ba-L, HIV-1_JRFL and HIV-1_MOKW.

HY-152132

CCR5 antagonist 3	CCR HIV	Infection
CCR5 antagonist 3 (Compound 26) is a CCR5 antagonist with an IC₅₀ of 15.90 nM. CCR5 antagonist 3 shows broad-spectrum anti-HIV-1 activities .

HY-152131

CCR5 antagonist 2	CCR HIV	Infection
CCR5 antagonist 2 (Compound 25) is a CCR5 antagonist with an IC₅₀ of 8.34 nM. CCR5 antagonist 2 shows broad-spectrum anti-HIV-1 activities .

HY-RS17119

Cel Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cel Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cel gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cel Mouse Pre-designed siRNA Set A Cel Mouse Pre-designed siRNA Set A

HY-114366

BC-1485	CXCR	Others
BC-1485 is a small molecule inhibitor of Fibrosis-inducing E3 ligase 1 (FIEL1). BC-1485 protects PIAS4 from ubiquitin-mediated degradation. BC-1485 decreases α-SMA, *BAL* and CXCL1. BC-1485 ameliorates fibrotic lung injury in murine models .

HY-123985

MFN2 agonist-1	Mitochondrial Metabolism	Others
MFN2 agonist-1 (B-A/l) potently stimulates mitochondrial fusion in mitofusin 2 (MFN2)-deficient cells. MFN2 agonist-1 reverses mitochondrial “clumping” (formation of static mitochondrial aggregates) and restores mitochondrial motility in cultured mouse neurons expressing the CMT2A mutant MFN2 T105M.

HY-RS10071

PARP9 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PARP9 Human Pre-designed siRNA Set A contains three designed siRNAs for PARP9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PARP9 Human Pre-designed siRNA Set A PARP9 Human Pre-designed siRNA Set A

HY-RS20074

Parp9 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Parp9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Parp9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Parp9 Mouse Pre-designed siRNA Set A Parp9 Mouse Pre-designed siRNA Set A

HY-RS02454

CEL Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CEL Human Pre-designed siRNA Set A contains three designed siRNAs for CEL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CEL Human Pre-designed siRNA Set A CEL Human Pre-designed siRNA Set A

HY-RS13148

SLC27A5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SLC27A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC27A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SLC27A5 Human Pre-designed siRNA Set A SLC27A5 Human Pre-designed siRNA Set A

Species:	Human (2) Mouse (1)
Tag:	His (2) Tag Free (1)
Source:	Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P74352

	Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His) Bile salt-activated lipase; BaL; BSSL; Cel; Lip1	Mouse	Sf9 insect cells
	Carboxyester lipase/CEL protein plays a crucial role in cellular processes as it catalyzes the hydrolysis of a variety of substrates, including cholesterol esters, phospholipids, lysophospholipids, diacylglycerols and triacylglycerols, and lipids of hydroxy fatty acids acid ester. FAHF). Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His) is the recombinant mouse-derived Carboxyl Ester Lipase/CEL protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P702072

	DTX3L Protein, Human DTX3L; E3 ubiquitin-protein ligase DTX3L; B-lymphoma- and BaL-associated protein; Protein deltex-3-like; RING-type E3 ubiquitin transferase DTX3L; Rhysin-2; Rhysin2	Human	E. coli
	DTX3L protein is an E3 ubiquitin protein ligase that cooperates with PARP9 in DNA damage repair and antiviral responses. It monoubiquitylates histones (H2A, H2B, H3, H4), especially “Lys-91” of H4, possibly signaling additional modifications. DTX3L Protein, Human is the recombinant human-derived DTX3L protein, expressed by E. coli , with tag free.

HY-P702073

	DTX3L Protein, Human (His) DTX3L; E3 ubiquitin-protein ligase DTX3L; B-lymphoma- and BaL-associated protein; Protein deltex-3-like; RING-type E3 ubiquitin transferase DTX3L; Rhysin-2; Rhysin2	Human	E. coli
	DTX3L protein is an E3 ubiquitin protein ligase that cooperates with PARP9 in DNA damage repair and antiviral responses. It monoubiquitylates histones (H2A, H2B, H3, H4), especially “Lys-91” of H4, possibly signaling additional modifications. DTX3L Protein, Human (His) is the recombinant human-derived DTX3L protein, expressed by E. coli , with N-6*His labeled tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Isavuconazole-d4
Isavuconazole-d₄ is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P84889

	SLC27A5 Antibody (YA4586) BaL; ACSB; BaCS; FATP5; ACSVL6; FACVL3; FATP-5; VLACSR; VLCSH2; VLCS-H2	IHC-P, ELISA	Human, Mouse
	SLC27A5 Antibody (YA4586) is a mouse-derived and non-conjugated IgG1 antibody, targeting to SLC27A5. It can be applicated for WB, IHC-P, ELISA assays, in the background of human, mouse.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Dsg3 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Dsg3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dsg3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cel Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Cel Rat Pre-designed siRNA Set A contains three designed siRNAs for Cel gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cel Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Cel Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cel gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

PARP9 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PARP9 Human Pre-designed siRNA Set A contains three designed siRNAs for PARP9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Parp9 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Parp9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Parp9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: