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BWA-6047

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-176128
    BWA-6047

    		PROTACs Androgen Receptor Molecular Glues Cancer
    BWA-6047 is a dual AR/AR-V7 and GSPT1 PROTAC degrader (AR: DC50 = 3.7 nM; AR-V7: DC50 = 3.0 nM; GSPT1: DC50 = 1.2 nM). BWA-6047 promotes ubiquitination and degradation of AR/AR-V7 and, through its molecular glue properties, induces the formation of a PPI between GSPT1 and CRBN, leading to GSPT1 degradation. BWA-6047 can be used in prostate cancer research (Pink: AR/AR-V7 ligand (HY-176129); Blue: E3 CRBN ligand (HY-W069604); Black: linker (HY-W069604)) .
    BWA-6047
  • HY-176129
    AR ligand 41

    		Ligands for Target Protein for PROTAC Cancer
    AR ligand 41 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). AR ligand 41 can be used for the synthesis of BWA-6047 (HY-176128) .
    AR ligand 41

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