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Results for "

BCL3

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-152177
    JS6

    		NF-κB Cancer
    JS6 is a Bcl3 inhibitor, and inhibits Bcl3-NF-kB1 binding. JS6 inhibits tumor cell growth in vitro and in vivo .
    JS6
  • HY-14454
    TPh A
    2 Publications Verification

    Triphenyl Compound A

    		 Others Cancer
    TPh A (Triphenyl Compound A) is a potent inhibitor of the nuclear protein pirin and binds specifically to pirin with a Ki of 0.6 uM. TPh A disrupts the formation of the bcl3–pirin complex. TPh A can be used as a novel small molecule tool to regulate pirin in cells .
    TPh A
  • HY-111152
    ML115
    4 Publications Verification

    		 STAT Cancer
    ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC50 of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-κB anti-targets. ML115 counteracts the effects of Ginsenoside Rc (HY-N0042) on cell viability and inflammatory responses in LPS (HY-D1056)-stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers .
    ML115
  • HY-RS18602
    Bcl3 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Bcl3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bcl3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Bcl3 Mouse Pre-designed siRNA Set A
    Bcl3 Mouse Pre-designed siRNA Set A
  • HY-RS25087
    Bcl3 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Bcl3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Bcl3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Bcl3 Rat Pre-designed siRNA Set A
    Bcl3 Rat Pre-designed siRNA Set A
  • HY-RS01437
    BCL3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    BCL3 Human Pre-designed siRNA Set A contains three designed siRNAs for BCL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    BCL3 Human Pre-designed siRNA Set A
    BCL3 Human Pre-designed siRNA Set A
  • HY-171579
    RS47

    		NF-κB Cancer
    RS47 (Compound 1a) is a selective inhibitor of the non-canonical NF-κB signaling pathway targeting RelB with a Kd of 1.1 μM. RS47 competitively blocks RelB binding to target DNA, inhibiting downstream gene (e.g., BCL3, PIM2) expression, thereby suppressing tumor cell proliferation. RS47 is promising for research of cancers with aberrant activation of the non-canonical NF-κB pathway, such as colorectal cancer and B lymphoma .
    RS47

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