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Results for "

BBC

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Recombinant Proteins

4

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162514
    BBC0403

    		Epigenetic Reader Domain Inflammation/Immunology
    BBC0403 is a selective BRD2 inhibitor with Kds of 7.64 μM and 41.37 μM for BRD2 (BD2) and BRD2 (BD1), respectively. BBC0403 exhibitS higher binding specificity for BRD2 compared to BRD3 and BRD4. BBC0403 has the potential for osteoarthritis (OA) research .
    BBC0403
  • HY-147098
    dTAG-47

    		PROTACs FKBP Cancer
    dTAG-47, heterobifunctional dTAG molecule, targets mutant FKBP12 (FKBP12 F36V). FKBP12 F36V serves as a degradation tag (dTAG) and is fused to a protein of interest. dTAG-47 can be used for the research of basal-like breast cancers (BBC) .
    dTAG-47
  • HY-RS01381
    BBC3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    BBC3 Human Pre-designed siRNA Set A contains three designed siRNAs for BBC3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    BBC3 Human Pre-designed siRNA Set A
    BBC3 Human Pre-designed siRNA Set A
  • HY-176535
    KB-0118

    BBC0115

    		 Epigenetic Reader Domain Interleukin Related STAT Inflammation/Immunology
    KB-0118 (BBC0115) is BET bromodomain inhibitor. KB-0118 selective binds to BRD2 and BRD4 over BRD3, with Kd values of 36.7 μM for BRD2 BD1 and 47.4 μM for BRD4 BD1. KB-0118 inhibits pro-inflammatory cytokines, including TNF, IL-1β, and IL-23a and selectively suppresses Th17 cell differentiation. KB-0118 modulates Th17-driven inflammation occurs through epigenetic suppression of BRD4, confirmed by downregulation of STAT3 and BRD4 target genes. KB-0118 has immunomodulatory effects in inflammatory bowel disease (IBD) model.
    KB-0118

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