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Pathways Recommended: GPCR/G Protein
Results for "

Apoptotic endonuclease G

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-176836
    PNR-3-82

    		Endonuclease Cancer
    PNR-3-82 is a selective Apoptotic endonuclease G (EndoG) inhibitor with an IC50 of 0.61  μM for EndoG over DNase I. PNR-3-82 does not inhibit five cell death-related enzymes including DNase II, RNase A, proteinase, lactate dehydrogenase and superoxide dismutase 1. PNR-3-82 has a cytoprotective activity and blocks Cisplatin (HY-17394) and Docetaxel (HY-B0011)-induced cell death. PNR-3-82 can be used for cell injuries research .
    PNR-3-82
  • HY-176835
    PNR-3-80

    		Endonuclease Cancer
    PNR-3-80 is a selective Apoptotic endonuclease G (EndoG) inhibitor with an IC50 of 0.67  μM for EndoG over DNase I. PNR-3-80 does not have inhibitory activities for DNase II, RNase A, proteinase, lactate dehydrogenase and superoxide dismutase 1. PNR-3-80 has a potent cytoprotective activity, and it significantly protects human prostate carcinoma cells from Cisplatin (HY-17394) and Docetaxel (HY-B0011)-induced cell death and represses Etoposide (HY-13629)-induced DNA damage and autophagy. PNR-3-80 can be used for cell injuries research .
    PNR-3-80

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