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Amino Acid Oxidase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Amino Acid Oxidase (4) Monoamine Oxidase (1) Xanthine Oxidase (2) Aryl Hydrocarbon Receptor (2) Bacterial (2) Biochemical Assay Reagents (2) Endogenous Metabolite (10) GABA Receptor (1) Histone Demethylase (1) iGluR (1) Isotope-Labeled Compounds (1) Reference Standards (4)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (1) Metabolic Disease (6) Neurological Disease (6)

Inhibitors & Agonists

Biochemical Assay Reagents

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Isotope-Labeled Compounds

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2987

L-Amino acid oxidase	Endogenous Metabolite Amino Acid Oxidase	Metabolic Disease
L-Amino acid oxidase is a homodimeric proteins containing flavin adenine dinucleotide. L-Amino acid oxidase can catalyze the stereospecific oxidative deamination of L-amino acids to α-keto acids and ammonia .

HY-P2986

*D-Amino* acid oxidase (Immobilized)**	Endogenous Metabolite Amino Acid Oxidase	Metabolic Disease
D-Amino acid oxidase is an enzyme to metabolize exogenous D-amino acids in animals for detoxifying action. D-Amino acid oxidase also modulates the level of D-serine in brain .

HY-E70082

Fructosyl amino acid oxidase	Biochemical Assay Reagents	Metabolic Disease
Fructosyl amino acid oxidase can be used to measure glycosylated protein. Glycosylated protein, especially glycosylated hemoglobin A1c, is an important marker to evaluate the efficacy of diabetes treatment .

HY-Y0127

D(-)-2-Aminobutyric acid 1 Publications Verification	Endogenous Metabolite	Others
D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.

HY-P2965

L-Lysine α-oxidase	Endogenous Metabolite	Cancer
L-Lysine α-oxidase is a potent anticancer agent. L-Lysine α-oxidase also a L-amino acid oxidase, deaminates L-lysine with the yield of H2O2, ammonia, and α-keto-ε-aminocaproate. L-Lysine α-oxidase shows cytotoxicity and anticancer activity .

HY-111412

DAAO inhibitor-1	iGluR	Neurological Disease
DAAO inhibitor-1 is a potent *D-amino* acid oxidase (DAAO) inhibitor with an IC₅₀** of 0.12 μM.

HY-116688

2-Hydroxy-4-(methylthio)butyric acid	Amino Acid Derivatives	Others
2-Hydroxy-4-(methylthio)butyric acid (2-Hydroxy-4-(Methylthio)-Butanoic Acid) is an orally active source of methionine. 2-Hydroxy-4-(methylthio)butyric acid reduces the expression of multiple mRNAs (BHMT, MTR, MAT1A, SAHH, and PCK1). 2-Hydroxy-4-(methylthio)butyric acid increases milk production in periparturient cows .

HY-W037417

DAO-IN-1	Xanthine Oxidase	Others
DAO-IN-1 is a potent inhibitor of D-amino acid oxidase (DAO) with an IC₅₀ value of 269 nM. DAO is an enzyme responsible for D-serine metabolism, D-serine is a co-agonist of NMDA receptors .

HY-W039920

1-Amino-1-deoxy-β-D-galactose, 98% β-D-Galactosylamine, 98%	Biochemical Assay Reagents	Others
1-Amino-1-deoxy-β-D-galactose, 98% is a galactose analog used as a competitive inhibitor to aid in the separation, purification, identification, differentiation, and characterization of β-D-galactosidase and galactose oxidase.

HY-Y0127S

D(-)-2-Aminobutyric acid-d6	Isotope-Labeled Compounds Endogenous Metabolite	Others
D(-)-2-Aminobutyric acid-d₆ is the deuterium labeled D(-)-2-Aminobutyric acid. D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.

HY-N14924

Oganomycin GA	Bacterial	Infection
Oganomycin GA is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria .

HY-Y0127R

D(-)-2-Aminobutyric acid (Standard)	Reference Standards Endogenous Metabolite	Others
D(-)-2-Aminobutyric acid (Standard) is the analytical standard of D(-)-2-Aminobutyric acid. This product is intended for research and analytical applications. D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.

HY-N14926

Oganomycin GB	Bacterial	Infection
Oganomycin GB is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria. The antibacterial activity of A and B was higher than that of GA and GB .

HY-117292

DAO-IN-2	Amino Acid Oxidase	Neurological Disease
DAO-IN-2 is a d-amino acid oxidase (DAO) inhibitor (h-DAO IC₅₀ = 245 nM). DAO-IN-2 is a moderate inhibitor of DAAO in vitro and in vivo. DAO-IN-2 can be used to study DAAO-related psychiatric disorders .

HY-117292R

DAO-IN-2 (Standard)	Reference Standards Amino Acid Oxidase	Neurological Disease
DAO-IN-2 (Standard) is the analytical standard of DAO-IN-2 (HY-117292). This product is intended for research and analytical applications. DAO-IN-2 is a novel D-amino acid oxidase (DAO) inhibitor. DAO-IN-2 demonstrates moderate potency for DAO in vitro and ex vivo .

HY-W001959

D-Allothreonine	Endogenous Metabolite	Metabolic Disease
D-Allothreonine is the D stereoisomer of Allothreonine. D-Allallreonine is a peptide lipid derived from bacteria. D-Allothreonine can be specifically oxidized by D-amino acid oxidase, while the L configuration has no reaction. D-Allallreonine is also a component of bacterial polysaccharides. D-Allallreonine can be used for researching bacterial pathogenicity, antigenic diversity and drug resistance .

HY-109183

Luvadaxistat TAK-831	Xanthine Oxidase	Others
Luvadaxistat (TAK-831) is an orally active, highly selective, potent *D-amino* acid oxidase (DAAO)** inhibitor. Luvadaxistat inhibits oxidative deamination of D-serine via the human recombinant DAAO enzyme with an IC₅₀ of 14 nM. Luvadaxistat significantly increases D-serine levels in the rodent brain, plasma, and cerebrospinal fluid. Luvadaxistat has the potential for schizophrenia research .

HY-33009

AS057278	Others	Neurological Disease
AS057278 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant non-peptidic *D-amino* acid oxidase (DAAO) inhibitor with an IC₅₀ value of 0.91 μM and EC₅₀** of 2.2-3.95 μM. AS057278 can normalize phencyclidine (PCP)-induced prepulse inhibition in mice. AS057278 can be used for researching schizophrenia .

HY-W014502

D-Kynurenine	Aryl Hydrocarbon Receptor Endogenous Metabolite	Cancer
D-kynurenine, a metabolite of D-tryptophan, can serve as the bioprecursor of kynurenic acid (KYNA) and 3-hydroxykynurenine. D-Kynurenine is an agonist for G protein-coupled receptor, GPR109B. D-Kynurenine is a substrate in a fluorometric assay of D-amino acid oxidase. D-kynurenine promotes epithelial-to-mesenchymal transition via activating aryl hydrocarbon receptor (AHR) .

HY-W001959R

D-Allothreonine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
D-Allothreonine (Standard) is an analytical standard for D-Allothreonine (HY-001959). This product is intended for research and analytical applications. D-Allothreonine is the D-stereoisomer of allothreonine. D-Allothreonine is a bacterial peptide lipid. D-Allothreonine is specifically oxidized by D-amino acid oxidase, while the L-form is unresponsive. D-Allothreonine is also a component of bacterial polysaccharides. D-Allothreonine can be used to study bacterial pathogenicity, antigenic diversity, and drug resistance.

HY-W014502R

D-Kynurenine (Standard)	Reference Standards Aryl Hydrocarbon Receptor Endogenous Metabolite	Cancer
D-Kynurenine (Standard) is the analytical standard of D-Kynurenine. This product is intended for research and analytical applications. D-kynurenine, a metabolite of D-tryptophan, can serve as the bioprecursor of kynurenic acid (KYNA) and 3-hydroxykynurenine. D-Kynurenine is an agonist for G protein-coupled receptor, GPR109B. D-Kynurenine is a substrate in a fluorometric assay of D-amino acid oxidase. D-kynurenine promotes epithelial-to-mesenchymal transition via activating aryl hydrocarbon receptor (AHR) .

HY-33009R

AS057278 (Standard)	Others	Neurological Disease
AS057278 (Standard) is the analytical standard of AS057278. This product is intended for research and analytical applications. AS057278 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant non-peptidic D-amino acid oxidase (DAAO) inhibitor with an IC50 value of 0.91 μM and EC50 of 2.2-3.95 μM. AS057278 can normalize phencyclidine (PCP)-induced prepulse inhibition in mice. AS057278 can be used for researching schizophrenia .

HY-B1018A

Phenelzine sulfate 5+ Cited Publications	Monoamine Oxidase GABA Receptor Histone Demethylase	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (K_i: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer .

Cat. No.	Product Name	Type

HY-W039920

1-Amino-1-deoxy-β-D-galactose, 98% β-D-Galactosylamine, 98%	Carbohydrates
1-Amino-1-deoxy-β-D-galactose, 98% is a galactose analog used as a competitive inhibitor to aid in the separation, purification, identification, differentiation, and characterization of β-D-galactosidase and galactose oxidase.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0127

D(-)-2-Aminobutyric acid 1 Publications Verification	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.

HY-116688

2-Hydroxy-4-(methylthio)butyric acid	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Amino Acid Derivatives
2-Hydroxy-4-(methylthio)butyric acid (2-Hydroxy-4-(Methylthio)-Butanoic Acid) is an orally active source of methionine. 2-Hydroxy-4-(methylthio)butyric acid reduces the expression of multiple mRNAs (BHMT, MTR, MAT1A, SAHH, and PCK1). 2-Hydroxy-4-(methylthio)butyric acid increases milk production in periparturient cows .

HY-W001959

D-Allothreonine	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
D-Allothreonine is the D stereoisomer of Allothreonine. D-Allallreonine is a peptide lipid derived from bacteria. D-Allothreonine can be specifically oxidized by D-amino acid oxidase, while the L configuration has no reaction. D-Allallreonine is also a component of bacterial polysaccharides. D-Allallreonine can be used for researching bacterial pathogenicity, antigenic diversity and drug resistance .

HY-W014502

D-Kynurenine	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Cancer	Aryl Hydrocarbon Receptor Endogenous Metabolite
D-kynurenine, a metabolite of D-tryptophan, can serve as the bioprecursor of kynurenic acid (KYNA) and 3-hydroxykynurenine. D-Kynurenine is an agonist for G protein-coupled receptor, GPR109B. D-Kynurenine is a substrate in a fluorometric assay of D-amino acid oxidase. D-kynurenine promotes epithelial-to-mesenchymal transition via activating aryl hydrocarbon receptor (AHR) .

HY-N14924

Oganomycin GA	Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial
Oganomycin GA is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria .

HY-Y0127R

D(-)-2-Aminobutyric acid (Standard)	Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
D(-)-2-Aminobutyric acid (Standard) is the analytical standard of D(-)-2-Aminobutyric acid. This product is intended for research and analytical applications. D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.

HY-N14926

Oganomycin GB	Natural Products Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial
Oganomycin GB is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria. The antibacterial activity of A and B was higher than that of GA and GB .

HY-W001959R

D-Allothreonine (Standard)	Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
D-Allothreonine (Standard) is an analytical standard for D-Allothreonine (HY-001959). This product is intended for research and analytical applications. D-Allothreonine is the D-stereoisomer of allothreonine. D-Allothreonine is a bacterial peptide lipid. D-Allothreonine is specifically oxidized by D-amino acid oxidase, while the L-form is unresponsive. D-Allothreonine is also a component of bacterial polysaccharides. D-Allothreonine can be used to study bacterial pathogenicity, antigenic diversity, and drug resistance.

HY-W014502R

D-Kynurenine (Standard)	Ketones, Aldehydes, Acids Endogenous metabolite	Reference Standards Aryl Hydrocarbon Receptor Endogenous Metabolite
D-Kynurenine (Standard) is the analytical standard of D-Kynurenine. This product is intended for research and analytical applications. D-kynurenine, a metabolite of D-tryptophan, can serve as the bioprecursor of kynurenic acid (KYNA) and 3-hydroxykynurenine. D-Kynurenine is an agonist for G protein-coupled receptor, GPR109B. D-Kynurenine is a substrate in a fluorometric assay of D-amino acid oxidase. D-kynurenine promotes epithelial-to-mesenchymal transition via activating aryl hydrocarbon receptor (AHR) .

Cat. No.	Compare	Product Name	Species	Source

HY-P7898

	*D-amino-acid oxidase/DAO Protein, Human (His)* rHuD-Amino-Acid Oxidase/DAO, His; D-Amino-Acid Oxidase; DAAO; DAMOX; DAO	Human	E. coli
	D-amino-acid oxidase Protein, Human (His) is a recombinant D-amino-acid oxidase protein with a His tag. D-amino acid oxidase (DAO) is a flavin adenine dinucleotide (FAD)-dependent oxidase metabolizing neutral and polar D-amino acids.

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HY-Y0127S

D(-)-2-Aminobutyric acid-d6
D(-)-2-Aminobutyric acid-d₆ is the deuterium labeled D(-)-2-Aminobutyric acid. D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.

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HY-P81480

	IL-4I1/LAO Antibody (YA1225) IL4I1; FIG1 ; UNQ636/PRO1265 ; L-Amino-Acid Oxidase ; Interleukin-4-induced protein 1; hIL4I1 ; Protein Fig-1 ; LAAO; LAO	IHC-P	Human
	IL-4I1/LAO Antibody (YA1225) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-4I1/LAO.

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Amino Acid Oxidase

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Natural
Products