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Amino Acid Decarboxylase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Decarboxylase (4) 5-HT Receptor (2) Amyloid-β (4) Autophagy (9) COMT (1) Drug Metabolite (9) Endogenous Metabolite (20) ERK (4) GABA Receptor (2) Isotope-Labeled Compounds (8) NF-κB (1) Pyruvate Kinase (4) Reference Standards (4)
By Research Areas:	Cancer (8) Infection (1) Inflammation/Immunology (1) Metabolic Disease (18) Neurological Disease (24)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Amino Acid Decarboxylase Amino acid Transporter Amino Acid Oxidase Amino Acid Derivatives Ornithine decarboxylase (ODC) Malonyl-CoA Decarboxylase EAAT Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N3394

Lecanoric acid	Others	Infection
Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase .

HY-113305

Dopamine 3-O-sulfate	Endogenous Metabolite	Metabolic Disease
Dopamine 3-O-sulfate mainly exists in plasma and can be used as a biomarker to characterize aromatic amino acid decarboxylase (AADC) deficiency .

HY-112619

TES-991 1 Publications Verification	Others	Metabolic Disease
TES-991 is a potent and selective human α Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) inhibitor, with an IC₅₀ of 3 nM.

HY-N0384

Homovanillic acid Vanilacetic Acid	Drug Metabolite Endogenous Metabolite Autophagy	Metabolic Disease
Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-111365

TES-1025 3 Publications Verification	Others	Metabolic Disease
TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC₅₀ of 13 nM .

HY-N0122

5-Hydroxytryptophan 1 Publications Verification 5-HTP; DL-5-Hydroxytryptophan	Endogenous Metabolite 5-HT Receptor	Neurological Disease Metabolic Disease
5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. .

HY-B0404A

Benserazide hydrochloride Maximum Cited Publications 6 Publications Verification Ro 4-4602 hydrochloride	Pyruvate Kinase	Neurological Disease Cancer
Benserazide hydrochloride (Serazide) is an *aromatic L-amino* acid decarboxylase (AADC)** and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2 inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .

HY-W015595

L-Allylglycine hydrochloride 1 Publications Verification L-2-Allylglycine hydrochloride	Amino Acid Decarboxylase GABA Receptor	Neurological Disease
L-Allylglycine (L-2-Allylglycine) hydrochloride is an amino acid derivative. L-Allylglycine hydrochloride is an inhibitor for *glutamate decarboxylase* (GAD)** that reduces the GABA biosynthesis in the brain. L-Allylglycine hydrochloride exhibits convulsant activity .

HY-122968

Brocresine NSD-1065	Endogenous Metabolite	Neurological Disease
Brocresine (NSD-1065) is an orally active histidine decarboxylase inhibitor and inhibits the formation of histamine from histidine. Brocresine is also a L-amino acid decarboxylase inhibitor with both a peripheral and central action. Brocresine inhibits gastric secretory response to administration of exogenous gastrin .

HY-121275

Benserazide Ro 4-4602	Pyruvate Kinase	Neurological Disease Cancer
Benserazide is an *aromatic L-amino* acid decarboxylase (AADC)** and L-DOPA decarboxylase inhibitor. Benserazide is also a PKM2 inhibitor. Benserazide directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide can be used for the study of Parkinson's disease and melanoma .

HY-W012906

L-Allylglycine 1 Publications Verification L-2-Allylglycine	Amino Acid Decarboxylase GABA Receptor	Neurological Disease
L-Allylglycine (L-2-Allylglycine) is an amino acid derivative. L-Allylglycine is an inhibitor for *glutamate decarboxylase* (GAD)** that reduces the GABA biosynthesis in the brain. L-Allylglycine exhibits convulsant activity .

HY-W003445

4-Bromo-3-hydroxybenzoic acid	Endogenous Metabolite	Neurological Disease
4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a *histidine decarboxylase* (HDC) inhibitor with IC₅₀s of 1 mM for both rat fetal and rat gastric HDC*. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino* acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC₅₀s of 1 mM for both enzymes .

HY-113468

3-O-Methyl-DL-DOPA 3-Methoxytyrosine	Endogenous Metabolite	Neurological Disease
3-O-Methyl-DL-DOPA is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Epilepsy, Purine Nucleoside Phosphorylase Deficiency and Aromatic L Amino Acid Decarboxylase Deficiency .

HY-B0404AS

Benserazide-d3 hydrochloride Ro 4-4602-d₃ hydrochloride	Isotope-Labeled Compounds Pyruvate Kinase	Neurological Disease Cancer
Benserazide-d₃ (hydrochloride) is the deuterium labeled Benserazide hydrochloride (HY-B0404A). Benserazide hydrochloride (Serazide) is an *aromatic L-amino* acid decarboxylase (AADC)** and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2 inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .

HY-B0404AR

Benserazide hydrochloride (Standard) Ro 4-4602 hydrochloride (Standard)	Reference Standards Pyruvate Kinase	Neurological Disease Cancer
Benserazide hydrochloride (Standard) (Serazide (Standard)) is the analytical standard of Benserazide hydrochloride (HY-B0404A). This product is intended for research and analytical applications. Benserazide hydrochloride (Serazide) is an *aromatic L-amino* acid decarboxylase (AADC)** and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2 inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .

HY-W777477

Homovanillic Acid-13C6 Vanilacetic Acid-¹³C₆	Isotope-Labeled Compounds Autophagy Drug Metabolite Endogenous Metabolite	Metabolic Disease
Homovanillic Acid- ¹³C₆ (Vanilacetic acid- ¹³C₆) is the ¹³C-labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

HY-N0122R

5-Hydroxytryptophan (Standard)	Endogenous Metabolite 5-HT Receptor	Neurological Disease Metabolic Disease
5-Hydroxytryptophan (Standard) is the analytical standard of 5-Hydroxytryptophan. This product is intended for research and analytical applications. 5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. .

HY-N0384R

Homovanillic acid (Standard) Vanilacetic Acid (Standard)	Reference Standards Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid (Standard) (Vanilacetic acid (Standard)) is the analytical standard of Homovanillic acid (HY-N0384). This product is intended for research and analytical applications. Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S

Homovanillic acid-d3 Vanilacetic Acid-d₃	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid-d₃ (Vanilacetic acid-d₃) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S2

Homovanillic acid-d5 Vanilacetic Acid-d₅	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid-d₅ (Vanilacetic acid-d₅) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S1

Homovanillic acid-d2 Vanilacetic Acid-d₂	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid-d₂ (Vanilacetic acid-d₂) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S4

Homovanillic acid-d3-1 Vanilacetic Acid-d₃-1	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid-d₃-1 (Vanilacetic acid-d₃-1) is deuterated labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S3

Homovanillic acid-13C6,18O Vanilacetic Acid-¹³C₆,¹⁸O	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid- ¹³C₆, ¹⁸O (Vanilacetic acid- ¹³C₆, ¹⁸O) is the ¹³C- and ¹⁸O-labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S5

Homovanillic acid-13C,d3 Vanilacetic Acid-¹³C,d₃	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid- ¹³C,d₃ (Vanilacetic acid- ¹³C,d₃) is ¹³C and deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N3548

Catalpalactone	NF-κB	Inflammation/Immunology
Catalpalactone has anti-inflammatory effect. Catalpalactone inhibits LPS-induced NO production and iNOS expression in RAW264.7 cells, and also inhibits IRF3, NF-κB, and IFN-β/STAT-1 activation. Catalpalactone also inhibits dopamine biosynthesis by reducing tyrosine hydroxylase (TH) and aromatic-l-amino acid decarboxylase (AADC) activities .

HY-W012264

3-O-Methyldopa monohydrate 1 Publications Verification 3-Methoxy-L-tyrosine monohydrate; 3-O-Methyl-L-DOPA monohydrate	COMT	Neurological Disease
3-O-Methyldopa monohydrate (3-Methoxy-L-tyrosine monohydrate) is a significant metabolite of L-DOPA produced through the action of catechol O-methyltransferase (COMT). Unlike its precursor, 3-O-Methyldopa does not serve as a substrate or inhibitor of L-amino acid decarboxylase activity. Additionally, the inhibition of COMT can amplify the anti-Parkinson effects of L-DOPA.

HY-113468R

3-O-Methyl-DL-DOPA (Standard) 3-Methoxytyrosine (Standard)	Endogenous Metabolite Reference Standards	Neurological Disease
3-O-Methyl-DL-DOPA (Standard) is the analytical standard of 3-O-Methyl-DL-DOPA. This product is intended for research and analytical applications. 3-O-Methyl-DL-DOPA is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Epilepsy, Purine Nucleoside Phosphorylase Deficiency and Aromatic L Amino Acid Decarboxylase Deficiency [4].

HY-W011727

Pyridoxal 5'-phosphate hydrate 2 Publications Verification Pyridoxal phosphate hydrate	Endogenous Metabolite Amyloid-β ERK	Neurological Disease Metabolic Disease Cancer
Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-W011727A

Pyridoxal 5'-phosphate monohydrate 2 Publications Verification Pyridoxal phosphate monohydrate	Endogenous Metabolite Amyloid-β ERK	Neurological Disease Metabolic Disease Cancer
Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) .

HY-W011727S

Pyridoxal Phosphate-d3 Pyridoxal 5'-phosphate-d₃	Endogenous Metabolite Amyloid-β ERK	Neurological Disease Metabolic Disease Cancer
Pyridoxal Phosphate-d₃ is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-W011727AR

Pyridoxal 5'-?phosphate monohydrate (Standard) Pyridoxal phosphate monohydrate (Standard)	Reference Standards Endogenous Metabolite Amyloid-β ERK	Neurological Disease Metabolic Disease Cancer
Pyridoxal 5'-phosphate (monohydrate) (Standard) is the analytical standard of Pyridoxal 5'-phosphate (monohydrate). This product is intended for research and analytical applications. Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-P5396A

GAD65 (524-543) acetate	Amino Acid Decarboxylase	Others
GAD65 (524-543) acetate is a biological active peptide with amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). GAD65 (524-543) acetate is one of the first fragments of the islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. GAD65 (524-543) acetate is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with GAD65 (524-543) acetate increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells .

HY-P5396

GAD65 (524-543)	Amino Acid Decarboxylase	Others
GAD65 (524-543) is a biological active peptide with amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). GAD65 (524-543) is one of the first fragments of islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. GAD65 (524-543) is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with GAD65 (524-543) increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells .

Cat. No.	Product Name	Target	Research Area

HY-W015595

L-Allylglycine hydrochloride 1 Publications Verification L-2-Allylglycine hydrochloride	Amino Acid Decarboxylase GABA Receptor	Neurological Disease
L-Allylglycine (L-2-Allylglycine) hydrochloride is an amino acid derivative. L-Allylglycine hydrochloride is an inhibitor for *glutamate decarboxylase* (GAD)** that reduces the GABA biosynthesis in the brain. L-Allylglycine hydrochloride exhibits convulsant activity .

HY-W012906

L-Allylglycine 1 Publications Verification L-2-Allylglycine	Amino Acid Decarboxylase GABA Receptor	Neurological Disease
L-Allylglycine (L-2-Allylglycine) is an amino acid derivative. L-Allylglycine is an inhibitor for *glutamate decarboxylase* (GAD)** that reduces the GABA biosynthesis in the brain. L-Allylglycine exhibits convulsant activity .

HY-P5396A

GAD65 (524-543) acetate	Amino Acid Decarboxylase	Others
GAD65 (524-543) acetate is a biological active peptide with amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). GAD65 (524-543) acetate is one of the first fragments of the islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. GAD65 (524-543) acetate is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with GAD65 (524-543) acetate increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells .

HY-P5396

GAD65 (524-543)	Amino Acid Decarboxylase	Others
GAD65 (524-543) is a biological active peptide with amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). GAD65 (524-543) is one of the first fragments of islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. GAD65 (524-543) is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with GAD65 (524-543) increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3394

Lecanoric acid	Infection Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	Others
Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase .

HY-113305

Dopamine 3-O-sulfate	Natural Products Classification of Application Fields Animals Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Dopamine 3-O-sulfate mainly exists in plasma and can be used as a biomarker to characterize aromatic amino acid decarboxylase (AADC) deficiency .

HY-N0384

Homovanillic acid Vanilacetic Acid	Monophenols Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields	Drug Metabolite Endogenous Metabolite Autophagy
Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0122

5-Hydroxytryptophan 1 Publications Verification 5-HTP; DL-5-Hydroxytryptophan	Monophenols Classification of Application Fields Source classification Disease markers Phenols Endocrine diseases Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite 5-HT Receptor
5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. .

HY-W003445

4-Bromo-3-hydroxybenzoic acid	Monophenols Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a *histidine decarboxylase* (HDC) inhibitor with IC₅₀s of 1 mM for both rat fetal and rat gastric HDC*. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino* acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC₅₀s of 1 mM for both enzymes .

HY-113468

3-O-Methyl-DL-DOPA 3-Methoxytyrosine	Monophenols Neurological Disease Classification of Application Fields Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-O-Methyl-DL-DOPA is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Epilepsy, Purine Nucleoside Phosphorylase Deficiency and Aromatic L Amino Acid Decarboxylase Deficiency .

HY-N0384R

Homovanillic acid (Standard) Vanilacetic Acid (Standard)	Monophenols Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Nervous System Disorder Endogenous metabolite	Reference Standards Autophagy Endogenous Metabolite Drug Metabolite
Homovanillic acid (Standard) (Vanilacetic acid (Standard)) is the analytical standard of Homovanillic acid (HY-N0384). This product is intended for research and analytical applications. Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-113468R

3-O-Methyl-DL-DOPA (Standard) 3-Methoxytyrosine (Standard)	Monophenols Source classification Phenols Endogenous metabolite	Endogenous Metabolite Reference Standards
3-O-Methyl-DL-DOPA (Standard) is the analytical standard of 3-O-Methyl-DL-DOPA. This product is intended for research and analytical applications. 3-O-Methyl-DL-DOPA is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Epilepsy, Purine Nucleoside Phosphorylase Deficiency and Aromatic L Amino Acid Decarboxylase Deficiency [4].

HY-N0122R

5-Hydroxytryptophan (Standard)	Monophenols Source classification Disease markers Phenols Endocrine diseases Amino acids Endogenous metabolite	Endogenous Metabolite 5-HT Receptor
5-Hydroxytryptophan (Standard) is the analytical standard of 5-Hydroxytryptophan. This product is intended for research and analytical applications. 5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. .

HY-N3548

Catalpalactone	Natural Products Catalpa ovata G. Don Source classification Plants Bignoniaceae	NF-κB
Catalpalactone has anti-inflammatory effect. Catalpalactone inhibits LPS-induced NO production and iNOS expression in RAW264.7 cells, and also inhibits IRF3, NF-κB, and IFN-β/STAT-1 activation. Catalpalactone also inhibits dopamine biosynthesis by reducing tyrosine hydroxylase (TH) and aromatic-l-amino acid decarboxylase (AADC) activities .

HY-W011727

Pyridoxal 5'-phosphate hydrate 2 Publications Verification Pyridoxal phosphate hydrate	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Amyloid-β ERK
Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-W011727A

Pyridoxal 5'-phosphate monohydrate 2 Publications Verification Pyridoxal phosphate monohydrate	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Amyloid-β ERK
Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) .

HY-W011727AR

Pyridoxal 5'-?phosphate monohydrate (Standard) Pyridoxal phosphate monohydrate (Standard)	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Amyloid-β ERK
Pyridoxal 5'-phosphate (monohydrate) (Standard) is the analytical standard of Pyridoxal 5'-phosphate (monohydrate). This product is intended for research and analytical applications. Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

Species:	Human (3) Mouse (1)
Tag:	His (3) Tag Free (1) Strep (1)
Source:	sf9 insect cells (1) Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P701909

	DDC Protein, Human DDC; Aromatic-L-Amino-Acid Decarboxylase; AADC; DOPA Decarboxylase; DDC	Human	E. coli
	DDC protein plays a central role in neurotransmitter synthesis by catalyzing the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to produce dopamine and L-5-hydroxytryptophan to produce serotonin. DDC Protein, Human is the recombinant human-derived DDC protein, expressed by E. coli , with tag free.

HY-P74204

	DDC Protein, Mouse (sf9, His) Aromatic-L-Amino-Acid Decarboxylase; AADC; DOPA Decarboxylase; DDC	Mouse	Sf9 insect cells
	The DDC protein plays a key role in neurotransmitter synthesis as it catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to produce dopamine and L-5-hydroxytryptophan to produce serotonin. These enzymatic reactions represent key steps in neurotransmitter biosynthesis and are essential for the normal functioning of the central nervous system. DDC Protein, Mouse (sf9, His) is the recombinant mouse-derived DDC protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P701910

	DDC Protein, Human (His, Strep II) DDC; Aromatic-L-Amino-Acid Decarboxylase; AADC; DOPA Decarboxylase; DDC	Human	E. coli
	DDC protein plays a central role in neurotransmitter synthesis by catalyzing the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to produce dopamine and L-5-hydroxytryptophan to produce serotonin. DDC Protein, Human (His, Strep II) is the recombinant human-derived DDC protein, expressed by E. coli , with N-Strep II, N-6*His labeled tag.

HY-P704655

	DDC Protein, Human (Sf9, His) DDC; Aromatic-L-Amino-Acid Decarboxylase; AADC; DOPA Decarboxylase; DDC	Human	sf9 insect cells
	DDC protein plays a central role in neurotransmitter synthesis by catalyzing the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to produce dopamine and L-5-hydroxytryptophan to produce serotonin. DDC Protein, Human (Sf9, His) is the recombinant human-derived DDC protein, expressed by sf9 insect cells, with C-His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-N0384S

Homovanillic acid-d3
Homovanillic acid-d₃ (Vanilacetic acid-d₃) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S2

Homovanillic acid-d5
Homovanillic acid-d₅ (Vanilacetic acid-d₅) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S3

Homovanillic acid-13C6,18O
Homovanillic acid- ¹³C₆, ¹⁸O (Vanilacetic acid- ¹³C₆, ¹⁸O) is the ¹³C- and ¹⁸O-labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-W011727S

Pyridoxal Phosphate-d3

Pyridoxal Phosphate-d₃ is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-B0404AS

Benserazide-d3 hydrochloride

Benserazide-d₃ (hydrochloride) is the deuterium labeled Benserazide hydrochloride (HY-B0404A). Benserazide hydrochloride (Serazide) is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2 inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .

HY-W777477

Homovanillic Acid-13C6
Homovanillic Acid- ¹³C₆ (Vanilacetic acid- ¹³C₆) is the ¹³C-labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

HY-N0384S1

Homovanillic acid-d2
Homovanillic acid-d₂ (Vanilacetic acid-d₂) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S4

Homovanillic acid-d3-1
Homovanillic acid-d₃-1 (Vanilacetic acid-d₃-1) is deuterated labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S5

Homovanillic acid-13C,d3
Homovanillic acid- ¹³C,d₃ (Vanilacetic acid- ¹³C,d₃) is ¹³C and deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

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HY-P82683

	DOPA Decarboxylase Antibody (YA2428) AADC; Aromatic L Amino Acid Decarboxylase; DDC; DOPA Decarboxylase (aromatic L-Amino Acid Decarboxylase); DOPA Decarboxylase	WB	Human, Mouse, Rat
	DOPA Decarboxylase Antibody (YA2428) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DOPA Decarboxylase.

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Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

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