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Results for "

Agelas

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125132
    Agelastatin A

    (-)-Agelastatin A; AglA

    		 Apoptosis Cancer
    Agelastatin A ((-)-Agelastatin A; AglA), a tetracyclic alkaloid isolated from the sponge Agelas dendromorpha, induces apoptosis and arrests cells in the G2/M phase of the cell cycle, exhibiting antitumor activity .
    Agelastatin A
  • HY-N1662
    2,4,6,6-Tetramethyl-3(6H)-pyridinone

    		Others Others
    2,4,6,6-Tetramethyl-3(6H)-pyridinone is a natural product that can be isolated from the tropical marine sponge Agelas oroides .
    2,4,6,6-Tetramethyl-3(6H)-pyridinone
  • HY-N7747
    Sceptrin dihydrochloride

    		Others Infection
    Sceptrin dihydrochloride is a compound isolated from the sea sponge Agelas sceptrum that is an antimicrobial agent .
    Sceptrin dihydrochloride
  • HY-113621B
    Ageladine A dihydrochloride

    		Fluorescent Dye MMP Cancer
    Ageladine A dihydrochloride is an inhibitor of matrix metalloproteinase (MMP) isolated from the marine sponge Agelas nakamurai, possessing anti-angiogenic activity. Ageladine A dihydrochloride not only inhibits MMP-2 but also MMP-1, MMP-8, MMP-9, MMP-12, and MMP-13, with IC50 values of 4.65 μM, 2.79 μM, 907.12 nM, 1.83 μM, 767.57 nM, and 1.09 μM, respectively. Additionally, Ageladine A dihydrochloride is a pH-sensitive membrane-permeable dye that emits fluorescence in the blue-green range upon UV excitation, featuring a maximum absorption peak at 370 nm. Furthermore, Ageladine A dihydrochloride serves as a reliable and stable fluorescent pH sensor for detecting changes in intracellular pH values .
    Ageladine A dihydrochloride
  • HY-116436
    Clathrodin

    		Sodium Channel Neurological Disease
    Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance .
    Clathrodin
  • HY-123888
    Viomellein

    		E1/E2/E3 Enzyme Bacterial Cancer
    Viomellein is a SUMOylation inhibitor with antibacterial and anticancer activities. Viomellein inhibits biofilm formation of strains produced from the fungus Aspergillus ochraceus from the Mediterranean sponge Agelas oroides. Viomellein exhibits cytotoxicity against A2780 human ovarian cancer cells with an IC50 value of 5.0 μM. Viomellein also inhibits SUMOylation of RanGAP1 (GTPase activating protein) with an IC50 of 10.2 μM .
    Viomellein

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