Acetoacetyl-CoA sodium

By Targets:	Endogenous Metabolite (6) Fatty Acid Synthase (FASN) (2) Reference Standards (1)
By Research Areas:	Cancer (1) Metabolic Disease (7)

Targets Recommended: Sodium Phosphate Cotransporter Sodium Channel Acetyl-CoA synthetase Malonyl-CoA Decarboxylase Stearoyl-CoA Desaturase (SCD) HMG-CoA Reductase (HMGCR) Acetyl-CoA Carboxylase Apical Sodium-Dependent Bile Acid Transporter Na+/H+ Exchanger (NHE) SGLT Na+/K+ ATPase Acyltransferase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113408

Tiglyl carnitine 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
Tiglyl carnitine is found to be associated with celiac disease and mitochondrial acetoacetyl-CoA thiolase (T2) deficiency.

HY-Y1125

6-Methyluracil Pseudothymine	Endogenous Metabolite	Metabolic Disease
6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo .

HY-113408R

Tiglyl carnitine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Tiglyl carnitine (Standard) is the analytical standard of Tiglyl carnitine. This product is intended for research and analytical applications. Tiglyl carnitine is found to be associated with celiac disease and mitochondrial acetoacetyl-CoA thiolase (T2) deficiency.

HY-12325

GSK2194069 4 Publications Verification	Fatty Acid Synthase (FASN)	Cancer
GSK2194069 is a potent inhibitor of β-ketoyl reductase (KR) of fatty acid synthase (FASN), with an IC₅₀ value of 7.7 nM. GSK2194069 shows specifically inhibitory effect on FAS expressing cancer cells, by acting potent efficacy on acetoacetyl-CoA, NADPH with IC₅₀ or K_i values of 4.8 nM and 5.6 nM, respectively .

HY-117769

GSK837149A	Fatty Acid Synthase (FASN)	Metabolic Disease
GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (K_i=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer .

HY-N7392A

Acetoacetyl-CoA sodium hydrate 3-Oxobutanoyl-coenzyme A sodium hydrate	Endogenous Metabolite	Metabolic Disease
Acetoacetyl CoA sodium hydrate is the precursor of HMG-CoA in the mevalonate pathway. Acetoacetyl-CoA thiolase catalyzes the reaction to form acetoacetyl-CoA sodium hydrate from two acetyl-CoA molecules. Acetoacetyl CoA sodium hydrate is essential for cholesterol biosynthesis. Acetoacetyl-CoA sodium hydrate is also a intermediate in the biological breakdown and synthesis of fatty acids .

HY-N7392

*Acetoacetyl-CoA* 3-Oxobutanoyl-coenzyme A	Endogenous Metabolite	Metabolic Disease
Acetoacetyl CoA is the precursor of HMG-CoA in the mevalonate pathway. Acetoacetyl-CoA thiolase catalyzes the reaction to form acetoacetyl-CoA from two acetyl-CoA molecules. Acetoacetyl CoA is essential for cholesterol biosynthesis. Acetoacetyl-CoA is also a intermediate in the biological breakdown and synthesis of fatty acids .

HY-Y1125R

6-Methyluracil (Standard)	Endogenous Metabolite	Metabolic Disease
6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo .

Cat. No.	Product Name	Type

HY-N7392

*Acetoacetyl-CoA* 3-Oxobutanoyl-coenzyme A	Biochemical Assay Reagents
Acetoacetyl CoA is the precursor of HMG-CoA in the mevalonate pathway. Acetoacetyl-CoA thiolase catalyzes the reaction to form acetoacetyl-CoA from two acetyl-CoA molecules. Acetoacetyl CoA is essential for cholesterol biosynthesis. Acetoacetyl-CoA is also a intermediate in the biological breakdown and synthesis of fatty acids .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113408

Tiglyl carnitine 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Tiglyl carnitine is found to be associated with celiac disease and mitochondrial acetoacetyl-CoA thiolase (T2) deficiency.

HY-Y1125

6-Methyluracil Pseudothymine	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo .

HY-113408R

Tiglyl carnitine (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Tiglyl carnitine (Standard) is the analytical standard of Tiglyl carnitine. This product is intended for research and analytical applications. Tiglyl carnitine is found to be associated with celiac disease and mitochondrial acetoacetyl-CoA thiolase (T2) deficiency.

HY-N7392A

Acetoacetyl-CoA sodium hydrate 3-Oxobutanoyl-coenzyme A sodium hydrate	Structural Classification Alkaloids Microorganisms Classification of Application Fields Source classification Metabolic Disease Disease Research Fields Indole Alkaloids	Endogenous Metabolite
Acetoacetyl CoA sodium hydrate is the precursor of HMG-CoA in the mevalonate pathway. Acetoacetyl-CoA thiolase catalyzes the reaction to form acetoacetyl-CoA sodium hydrate from two acetyl-CoA molecules. Acetoacetyl CoA sodium hydrate is essential for cholesterol biosynthesis. Acetoacetyl-CoA sodium hydrate is also a intermediate in the biological breakdown and synthesis of fatty acids .

HY-N7392

*Acetoacetyl-CoA* 3-Oxobutanoyl-coenzyme A	Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Acetoacetyl CoA is the precursor of HMG-CoA in the mevalonate pathway. Acetoacetyl-CoA thiolase catalyzes the reaction to form acetoacetyl-CoA from two acetyl-CoA molecules. Acetoacetyl CoA is essential for cholesterol biosynthesis. Acetoacetyl-CoA is also a intermediate in the biological breakdown and synthesis of fatty acids .

HY-Y1125R

6-Methyluracil (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
6-Methyluracil (Pseudothymine), a metabolite of Uracil, can be used as an indicator of acetoacetyl-CoA (AACoA) accumulation. 6-Methyluracil exhibits antiradiation effect in vivo .

Species:	Human (5)
Tag:	His (4) Tag Free (1) Myc (1) Trx (1)
Source:	Sf9 insect cells (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P71041

	ACAT2 Protein, Human (Trx-His) Acetyl-CoA acetyltransferase cytosolic; Acetyl-CoA transferase-like protein; Cytosolic Acetoacetyl-CoA thiolase; ACTL; ACAT2	Human	E. coli
	ACAT2, Human (Trx-His) is the major ACAT enzyme in human hepatocytes. ACAT2, Human is an important regulator of susceptibility to the development of atherosclerosis.

HY-P701332

	ACAT2 Protein, Human (His, Myc) Acetyl-CoA acetyltransferase cytosolic; Acetyl-CoA transferase-like protein; Cytosolic Acetoacetyl-CoA thiolase; ACTL; ACAT2	Human	E. coli
	ACAT2 Protein is essential in cholesterol biosynthesis. ACAT2 Protein, Human (His, Myc) is the recombinant human-derived ACAT2 protein, expressed by E. coli , with N-10*His, C-Myc labeled tag.

HY-P74435

	AACS Protein, Human (sf9, His) Acetoacetyl-CoA synthetase; AACS; ACSF1	Human	Sf9 insect cells
	AACS proteins play a key role in cellular metabolism by converting acetoacetate in the cytoplasm into acetoacetyl-CoA (by similarity). As a ketone body utilizing enzyme, AACS helps synthesize essential cellular components including cholesterol and fatty acids (by similarity). AACS Protein, Human (sf9, His) is the recombinant human-derived AACS protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P78986A

	ACAT1 Protein, Human Acetyl-CoA Acetyltransferase; THIL; ACAT; Acetyl-CoA Acetyltransferase, Mitochondrial; Acetyl-Coenzyme A Acetyltransferase; Acetoacetyl Coenzyme A Thiolase; Acetoacetyl-CoA Thiolase; EC 2.3.1.9; MAT; T2; Mitochondrial Acetoacetyl-CoA Thiolase; Testicular	Human	E. coli
	The ACAT1 protein is a key enzyme in mitochondrial beta-oxidation and plays a crucial role in breaking down fatty acids into acetyl-CoA. In the final step, ACAT1 catalyzes the thiolytic cleavage of 3-oxoacyl-CoA to generate acetyl-CoA and shortened fatty acyl-CoA. ACAT1 Protein, Human is the recombinant human-derived ACAT1, expressed by E. coli, with tag-free. The total length of ACAT1 Protein, Human is 394 a.a..

HY-P78986

	ACAT1 Protein, Human (His) Acetyl-CoA Acetyltransferase; THIL; ACAT; Acetyl-CoA Acetyltransferase, Mitochondrial; Acetyl-Coenzyme A Acetyltransferase; Acetoacetyl Coenzyme A Thiolase; Acetoacetyl-CoA Thiolase; EC 2.3.1.9; MAT; T2; Mitochondrial Acetoacetyl-CoA Thiolase; Testicular	Human	E. coli
	The ACAT1 protein is a key enzyme in mitochondrial beta-oxidation and plays a crucial role in breaking down fatty acids into acetyl-CoA. In the final step, ACAT1 catalyzes the thiolytic cleavage of 3-oxoacyl-CoA to generate acetyl-CoA and shortened fatty acyl-CoA. ACAT1 Protein Protein, Human (His) is the recombinant human-derived ACAT1 protein, expressed by E. coli , with N-His labeled tag.

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HY-P87299

	ACAT2 Antibody (YA6982) Acat2 antibody; Acetoacetyl CoA thiolase antibody; Acetoacetyl Coenzyme A thiolase antibody; Acetyl CoA acetyltransferase antibody; Acetyl CoA transferase like protein antibody; acetyl Coenzyme A acetyltransferase 2 antibody; Acetyl-CoA acetyltransferase antibody; Acetyl-CoA transferase-like protein antibody; Acyl Coenzyme A cholesterol acyltransferase 2 antibody; Cytosolic Acetoacetyl-CoA thiolase antibody	WB, IHC-P, FC	Human, Mouse, Rat
	ACAT2 Antibody (YA6982) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACAT2.

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Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

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Acetoacetyl-CoA sodium

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