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AZddCTP

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-171574
    3′-Azido-2′,3′-dideoxy-CTP

    AZddCTP

    		 HIV DNA/RNA Synthesis Infection
    3′-Azido-2′,3′-dideoxy-CTP (AZddCTP) is a cytidine analog containing a 3-azido group. As a chain terminator, 3′-Azido-2′,3′-dideoxy-CTP can be incorporated into the nascent DNA chain by HIV reverse transcriptase. 3′-Azido-2′,3′-dideoxy-CTP terminates DNA synthesis due to the lack of a 3'-hydroxyl group, thereby inhibiting viral replication. 3′-Azido-2′,3′-dideoxy-CTP has IC50 values of 15.6 μM and 160.8 μM for WT HIV and AZT R HIV. 3′-Azido-2′,3′-dideoxy-CTP has antiviral activity .
    3′-Azido-2′,3′-dideoxy-CTP

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