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Results for "

ALCL

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

3

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18315
    Bayer-18

    		JAK Apoptosis Cancer
    Bayer-18 is an inhibitor for TYK2. Bayer-18 inhibits the viability of ALCL cell K299, SR786, Mac1 and Mac2a with IC50 of 2-3 µM, and induces apoptosis in K299 and SR786 .
    Bayer-18
  • HY-10192
    NVP-TAE 684
    10+ Cited Publications

    TAE 684

    		 Anaplastic lymphoma kinase (ALK) Apoptosis Cancer
    NVP-TAE 684 (TAE 684) is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM .
    NVP-TAE 684
  • HY-P99669
    Iratumumab

    MDX-060

    		 TNF Receptor Cancer
    Iratumumab (MDX-060) a human anti-CD30 IgG1κ monoclonal antibody. Iratumumab inhibits the growth of CD30-expressing tumor cells. Iratumumab can be used for research of Hodgkin's lymphoma (HL) and anaplastic large-cell lymphoma (ALCL) .
    Iratumumab
  • HY-12331
    KRCA-0008
    1 Publications Verification

    		 Ack1 Anaplastic lymphoma kinase (ALK) Apoptosis Cancer
    KRCA-0008 is a selective ALK/Ack1 inhibitor with IC50s of 12 and 4 nM for ALK and Ack1, respectively. KRCA-0008 can be used for the research of cancer .
    KRCA-0008
  • HY-P991553
    HeFi-1

    		TNF Receptor Apoptosis Inflammation/Immunology Cancer
    HeFi-1 is a mouse anti-CD30 IgG1 monoclonal antibody. HeFi-1 recognizes the ligand-binding site on CD30. HeFi-1 can inhibit the growth of tumor cells with high expression of CD30. HeFi-1 can induce eosinophil apoptosis. HeFi-1 can be used for research on cancer or inflammation conditions such as anaplastic large-cell lymphoma (ALCL) and asthma .
    HeFi-1
  • HY-149473
    AChE-IN-39

    		Cholinesterase (ChE) Neurological Disease
    AChE-IN-39 (Compound 7c) is an AChE inhibitor (IC50: 0.058 μM). AChE-IN-39 has DPPH scavenging activity. AChE-IN-39 improves the cognitive impairment in AlCl3-induced amnesia animal model. AChE-IN-39 can be used for research of Alzheimer's disease .
    AChE-IN-39
  • HY-108230
    ALK-IN-12

    		Anaplastic lymphoma kinase (ALK) Cancer
    ALK-IN-12 is a potent and orally active ALK inhibitor with an IC50 of 0.18 nM. ALK-IN-12 also inhibits IGF1R and InsR (IC50=20.3 and 90.6 nM). Antitumor activities .
    ALK-IN-12
  • HY-P991512
    SGN-30

    		Apoptosis Cancer
    SGN-30 is a chimeric antibody derived from a mouse antihuman CD30 antibody, AC10, with the variable regions of AC10 and human α 1 heavy chain and κ light chain constant regions. SGN-30 induces apoptosis and cell-cycle arrest in cancer cells. SGN-30 can be used for the study of Hodgkin lymphoma (HL) and anaplastic large cell lymphoma (ALCL) .
    SGN-30

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