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Results for "

AFB

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y0337A
    L-Cysteine hydrochloride
    5+ Cited Publications

    		 Endogenous Metabolite Metabolic Disease Cancer
    L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .
    L-Cysteine hydrochloride
  • HY-111444
    Auxinole
    Maximum Cited Publications
    13 Publications Verification

    		 E1/E2/E3 Enzyme Others
    Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and so inhibits auxin-responsive gene expression.
    Auxinole
  • HY-112730
    PEO-IAA
    5 Publications Verification

    2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid

    		 Others Others
    PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).
    PEO-IAA
  • HY-137877
    7-Acetoxy-4-methylcoumarin

    4-Methylumbelliferyl acetate

    		 Glutathione S-transferase Others
    7-Acetoxy-4-methylcoumarin is an inhibitor of GST.7-Acetoxy-4-methylcoumarin inhibits AFB1-DNA binding in vitro with 36.7% inhibition .
    7-Acetoxy-4-methylcoumarin
  • HY-Y0337AR
    L-Cysteine (hydrochloride) (Standard)

    		Endogenous Metabolite Metabolic Disease Cancer
    L-Cysteine (hydrochloride) (Standard) is the analytical standard of L-Cysteine (hydrochloride). This product is intended for research and analytical applications. L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) [4].
    L-Cysteine (hydrochloride) (Standard)
  • HY-129247
    Versicolorin A

    		Biochemical Assay Reagents Others
    Versicolorin A, a precursor of aflatoxin B1 (AFB1), can serve as an early indicator of aflatoxin (AF) contamination, even when AFs themselves are present at undetectable levels .
    Versicolorin A
  • HY-Y0790R
    Cuminaldehyde (Standard)

    		α-synuclein Infection Neurological Disease Inflammation/Immunology Cancer
    Cuminaldehyde Standard is the analytical standard of Cuminaldehyde. This product is intended for research and analytical applications. Cuminaldehyde is the main component of Cuminum cyminum and has multiple biological activities, including anti-inflammatory, anti-cancer, anti-diabetic, anti-injury, anti-neuropathy and antibacterial effects. Cuminaldehyde is an inhibitor of aldose reductase (IC50= 0.00085 mg/mL) and α-glucosidase (IC50=0.5 mg/mL). Cuminaldehyde also inhibits the fibrillation of α-synuclein and prevents its aggregation Cuminaldehyde can induce apoptosis in colon adenocarcinoma cells by targeting topoisomerase I and II. In addition, Cuminaldehyde also exerts anti-inflammatory activity by inhibiting lipoxygenase. Cuminaldehyde has a strong inhibitory effect on the growth of Aspergillus flavus and the biosynthesis of aflatoxin B1 (AFB1). Cuminaldehyde can exert anti-injury and anti-neuropathy effects by participating in opioid receptors, L-arginine/NO/cGMP pathways and anti-inflammatory effects. Cuminaldehyde has potential application value in the research of neurodegenerative diseases, cancer, diabetes and neuropathic pain diseases .
    Cuminaldehyde (Standard)

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