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AChE-IN-94

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175758
    AChE-IN-94

    		Cholinesterase (ChE) Amyloid-β Neurological Disease
    AChE-IN-94 is an orally active and blood-brain barrier penetrable AChE inhibitor with an IC50 of 0.40 μM and Ki of 0.28 μM. AChE-IN-94 prevents self-induced and AChE-mediated Aβ1-42 aggregation. AChE-IN-94 alleviates cognitive/memory deficits in Scopolamine (HY-N0296)-induced amnesic model. AChE-IN-94 can be used for the study of Alzheimer's disease (AD) .
    AChE-IN-94

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