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ACBI4

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-176792
    ACBI-4

    		PROTACs Ras Cancer
    ACBI-4 is a selective GTP-loaded active state of KRAS (KRAS(on)) PROTAC degrader. ACBI-4 has significant anti-proliferative effect and potently degrades multiple KRAS mutants in cancer cells, such as KRASG12R .
    ACBI-4
  • HY-176917
    E3 ligase Ligand 76

    		Ligands for E3 Ligase Cancer
    E3 ligase Ligand 76 is a E3 ligase ligand that can be used in the recruitment of VHL protein. E3 ligase Ligand 76 can be connected to the KRAS ligand (HY-162960) by a linker to synthesis of PROTAC KRAS(on) degrader ACBI-4 (HY-176792) .
    E3 ligase Ligand 76
  • HY-176918
    K-Ras ligand-Linker Conjugate 8

    		Target Protein Ligand-Linker Conjugates Ras Cancer
    K-Ras ligand-Linker Conjugate 8 is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for KRAS (HY-162960) and a PROTAC linker, which recruits E3 ligases. K-Ras ligand-Linker Conjugate 8 can be used for synthesis of PROTAC KRAS(on) degrader ACBI-4 (HY-176792) .
    K-Ras ligand-Linker Conjugate 8

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