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8-OH-DPAT

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112061
    8-OH-DPAT
    3 Publications Verification

    8-Hydroxy-DPAT

    		 5-HT Receptor Neurological Disease
    8-OH-DPAT is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5).
    8-OH-DPAT
  • HY-15688
    8-OH-DPAT hydrobromide
    3 Publications Verification

    8-Hydroxy-DPAT hydrobromide

    		 5-HT Receptor Neurological Disease
    8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site .
    8-OH-DPAT hydrobromide
  • HY-136621
    5-HT1A modulator 2 hydrochloride

    		5-HT Receptor Neurological Disease
    5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT (HY-112061), is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding .
    5-HT1A modulator 2 hydrochloride
  • HY-112061R
    8-OH-DPAT (Standard)

    		5-HT Receptor Neurological Disease
    8-OH-DPAT (Standard) is the analytical standard of 8-OH-DPAT. This product is intended for research and analytical applications. 8-OH-DPAT is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5).
    8-OH-DPAT (Standard)
  • HY-101377B
    S(-)-8-OH-DPAT hydrobromide

    S(-)-8-Hydroxy-2-dipropylaminotetralin hydrobromide

    		 5-HT Receptor Neurological Disease
    S(-)-8-OH-DPAT (S(-)-8-Hydroxy-2-dipropylaminotetralin) hydrobromide is an enantiomer of 8-OH-DPAT hydrobromide. 8-OH-DPAT hydrobromide is a potent, selective 5-HT1A agonist with a pIC50 of 8.19 .
    S(-)-8-OH-DPAT hydrobromide
  • HY-101377A
    R(+)-8-OH-DPAT hydrobromide

    (R)-8-Hydroxy-2-dipropylaminotetralin hydrobromide

    		 5-HT Receptor Neurological Disease
    R(+)-8-OH-DPAT ((R)-8-Hydroxy-2-dipropylaminotetralin) hydrobromide is a potent 5-HT1A agonist. R(+)-8-OH-DPAT potentiates SUL (HY-B1059)-induced dopamine (DA) release in the medial prefrontal cortex (mPFC) .
    R(+)-8-OH-DPAT hydrobromide
  • HY-137111
    p-MPPF dihydrochloride

    		5-HT Receptor PERK
    p-MPPF dihydrochloride is a selective 5-HT antagonist that dose-dependently antagonizes the reduction of phosphorylated Erk1/2 levels in the hippocampus induced by 8-OH-DPAT (HY-112061) in rats. p-MPPF dihydrochloride can be used for neurological disease research .
    p-MPPF dihydrochloride
  • HY-137111A
    p-MPPF

    		5-HT Receptor PERK
    p-MPPF is a selective 5-HT antagonist that dose-dependently antagonizes the reduction of phosphorylated Erk1/2 levels in the hippocampus induced by 8-OH-DPAT (HY-112061) in rats. p-MPPF can be used for neurological disease research .
    p-MPPF
  • HY-19283
    DU125530

    		5-HT Receptor Neurological Disease
    DU125530 is a potent and selective5-HT1A receptor antagonist with Ki values of 0.7, 890, 1200, 240, 750, 1100 nM for 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2A, 5-HT2C, 5-HT3, respectively. DU125530 shows antidepressant effects .
    DU125530

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