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Results for "

7α-Thiospironolactone

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

6

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130465
    7α-Thiospironolactone

    Deacetylspironolactone; Mercaptospironolactone

    		 Drug Metabolite Metabolic Disease
    7α-Thiospironolactone is the transformation product of spironolactone (HY-B0561), which can be obtained by the metabolism of Thermomyces lanuginosus .
    7α-Thiospironolactone
  • HY-P1193
    GR 82334

    		Neurokinin Receptor Neurological Disease
    GR 82334 is a potent and specific reversible tachykinin NK1 receptor antagonist . GR 82334 inhibits substance P-induced sensitization by blocking SP NK1 receptors in naked mole-rats .
    GR 82334
  • HY-P2223
    Hypeptin

    		Antibiotic Bacterial Infection
    Hypeptin is a cyclo-deposited peptide antibiotic produced by Lysobacter sp.K5869. Hypeptin blocks bacterial cell wall biosynthesis by binding to multiple undecaprenyl pyrophosphate-containing biosynthesis intermediates，forming a stoichiometric 2:1 complex. Hypeptin has antibacterial activity .
    Hypeptin
  • HY-P2101
    Micropeptin 478A

    		Ser/Thr Protease Cardiovascular Disease
    Micropeptin 478A is a plasmin inhibitor from cyanobacteria with an IC50 of 0.1 μg/mL. Micropeptin 478A can be used to study bleeding disorders .
    Micropeptin 478A
  • HY-P1709
    Protactin

    		Bacterial Infection
    Protactin is a pentapeptide lactone produced by Streptomyces cucumeris strain L703-4 (ATCC 53784) with significant antioxidant properties. Protactin can be converted to actinomycin Zp by ferrocyanide oxidation. Actinomycin Zp exhibits potent antibacterial activity in vitro and has significant antitumor effects against P-388 leukemia in a mouse model .
    Protactin
  • HY-P3990
    Coibamide A

    		VEGFR Autophagy Apoptosis Cancer
    Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, shows potent antiproliferative activity. Coibamide A induces autophagosome accumulation via an mTOR-independent mechanism. Coibamide A induces apoptosis. Coibamide A inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts .
    Coibamide A
  • HY-P1720
    Telomycin

    		Antibiotic Bacterial Infection
    Telomycin is a calcium-dependent antibiotic, which can be produced by Streptomyces. Telomycin inhibits gram-positive bacteria, including multidrug-resistant (MDR) pathogens .
    Telomycin

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