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6PPD-Q

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By Targets:	Isotope-Labeled Compounds (1) α-synuclein (1)

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Natural
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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*6PPD-Q* 1 Publications Verification 6PPD-Quinone	α-synuclein	Others
6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. 6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders .

HY-152039S1

6PPD-Q-13C6 6PPD-Quinone-¹³C₆	Isotope-Labeled Compounds	Others
6PPD-quinone- ¹³C₆ is the ¹³C labeled 6PPD-quinone .

Cat. No.	Product Name	Category	Target	Chemical Structure

*6PPD-Q* 1 Publications Verification 6PPD-Quinone	Quinones Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Other Diseases Benzene Quinones Endogenous metabolite Disease Research Fields	α-synuclein
6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. 6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders .

Cat. No.	Product Name	Chemical Structure

HY-152039S1

6PPD-Q-13C6
6PPD-quinone- ¹³C₆ is the ¹³C labeled 6PPD-quinone .

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