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Results for "

4’-Thioinosine

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W354479
    6-Thioinosine Phosphate

    Thioinosinic acid

    		 Drug Metabolite Inflammation/Immunology
    6-Thioinosine Phosphate (Thioinosinic acid) is an intermediate metabolite of azathioprine (HY-B0256). Azathioprine is a purine analog immunosuppressive drug .
    6-Thioinosine Phosphate
  • HY-128671
    6-​Thioinosine

    6TI; 6-Mercaptopurine riboside

    		 PPAR LXR JNK NO Synthase Metabolic Disease
    6-Thioinosine (6TI) is a purine antimetabolite and an anti-adipogenic agent. 6-Thioinosine reduces the mRNA levels of PPARγ and C/EBPα and downregulates the mRNA levels of PPARγ target genes (LPL, CD36, aP2, and LXRα). 6-Thioinosine exerts its anti-adipogenic effects by downregulating PPARγ through JNK-dependent iNOS upregulation. 6-Thioinosine can be used to study adipocyte dysfunction .
    6-​Thioinosine
  • HY-152617
    4’-Thioinosine

    		Nucleoside Antimetabolite/Analog Cancer
    4’-Thioinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    4’-Thioinosine
  • HY-154467
    2′-Deoxy-6-thioinosine

    		Nucleoside Antimetabolite/Analog Cancer
    2′-Deoxy-6-thioinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2′-Deoxy-6-thioinosine
  • HY-115755
    Thio-ITP

    6-Thioinosine 5′-triphosphate; 6-Mercaptopurine-riboside-5'-triphosphate; 6-Thio-ITP

    		 DNA/RNA Synthesis Cancer
    Thio-ITP (6-Thioinosine 5′-triphosphate) is an RNA polymerase activity competitive inhibitor. Thio-ITP has a high apparent affinity for the polymerases (RNA polymerase I Ki: 40.9 μM; RNA polymerase II Ki: 38.0 μM) .
    Thio-ITP

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