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Results for "

2-pyridone

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y0191
    α-Pyridone

    2-pyridone

    		 Endogenous Metabolite Bacterial Infection Metabolic Disease
    α-Pyridone (2-Pyridone) is an antibacterial agent. α-Pyridone can be synthesized via the 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination. α-Pyridone can also be used to synthesize a wide range of heterocyclic compounds [2].
    α-Pyridone
  • HY-W018171
    3,5,6-Trichloro-2-pyridinol
    1 Publications Verification

    TCPy

    		 Herbicide Metabolic Disease Inflammation/Immunology
    3,5,6-Trichloro-2-pyridinol (TCPy) is a chloride of 2-pyridone with oral activity. 3,5,6-Trichloro-2-pyridinol is the main degradation product of the herbicide Triclopyr and the insecticides Chlorpyrifos and chlorpyrifos-methyl. 3,5,6-Trichloro-2-pyridinol is associated with attention deficit hyperactivity disorder (ADHD) and decreased testosterone levels. 3,5,6-Trichloro-2-pyridinol causes hearing loss, hepatotoxicity and nephrotoxicity in mice [2] .
    3,5,6-Trichloro-2-pyridinol
  • HY-65036
    4-Bromo-2-hydroxypyridine

    4-Bromo-2-pyridone

    		 Biochemical Assay Reagents Drug Intermediate Neurological Disease
    4-Bromo-2-hydroxypyridine is an intermediate. 4-Bromo-2-hydroxypyridine can be used to synthesize M1 muscarinic acetylcholine receptor (M1 mAChR) positive allosteric modulators. 4-Bromo-2-hydroxypyridine can be used in the research of Alzheimer's disease and schizophrenia [2].
    4-Bromo-2-hydroxypyridine
  • HY-122643
    NITD-916

    		Bacterial Infection
    NITD-916, a 4-hydroxy-2-pyridone derivative, is an orally active mycobacterial enoyl reductase InhA inhibitor with an IC50 of 570 nM. NITD-916 forms a ternary complex with InhA and NADH to block access to the fatty acyl substrate binding pocket. NITD-916 inhibition of InhA reduces the synthesis of mycolic acids and results in cell death. NITD-916 has potent anti-tuberculosis effects [2].
    NITD-916
  • HY-Y0191R
    α-Pyridone (Standard)

    2-pyridone (Standard)

    		 Reference Standards Endogenous Metabolite Bacterial Infection Metabolic Disease
    α-Pyridone (Standard) is the analytical standard of α-Pyridone. This product is intended for research and analytical applications. α-Pyridone (2-Pyridone) is an antibacterial agent. α-Pyridone can be synthesized via the 1,4-addition of 2-(phenylsulfinyl)acetamide to α,β-unsaturated ketones followed by cyclization and sulfoxide elimination. α-Pyridone can also be used to synthesize a wide range of heterocyclic compounds [2].
    α-Pyridone (Standard)
  • HY-W018171R
    3,5,6-Trichloro-2-pyridinol (Standard)

    TCPy (Standard)

    		 Herbicide Reference Standards Others
    3,5,6-Trichloro-2-pyridinol (Standard) is the analytical standard of 3,5,6-Trichloro-2-pyridinol. This product is intended for research and analytical applications. 3,5,6-Trichloro-2-pyridinol (TCPy) is a chloride of 2-pyridone with oral activity. 3,5,6-Trichloro-2-pyridinol is the main degradation product of the herbicide Triclopyr and the insecticides Chlorpyrifos and chlorpyrifos-methyl. 3,5,6-Trichloro-2-pyridinol is associated with attention deficit hyperactivity disorder (ADHD) and decreased testosterone levels. 3,5,6-Trichloro-2-pyridinol causes hearing loss, hepatotoxicity and nephrotoxicity in mice.
    3,5,6-Trichloro-2-pyridinol (Standard)
  • HY-147692
    COX-2-IN-14

    		COX Inflammation/Immunology
    COX-2-IN-14 (compound 2a) is a potent and selective COX-2 (cyclooxygenase-2) inhibitor. COX-2-IN-14 shows effective binding at the active site of COX-2 co-crystal. COX-2-IN-14 exhibits a high level of in vivo anti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity in mice .
    COX-2-IN-14

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