Search Result
Results for "
2′-deoxycytidine
" in MedChemExpress (MCE) Product Catalog:
8
Biochemical Assay Reagents
21
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W010771
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dCTP disodium; 2′-deoxycytidine-5′-triphosphate disodium
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Biochemical Assay Reagents
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Others
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Deoxycytidine triphosphate (disodium) (dCTP (disodium); 2′-Deoxycytidine-5′-triphosphate (disodium)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-101400S
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-
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- HY-101400S3
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- HY-101400
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-
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- HY-101400A
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dCTP (trisodium) solution (100mM); 2′-deoxycytidine-5′-triphosphate (trisodium) solution (100mM)
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DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Metabolic Disease
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Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing [2] .
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-
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- HY-101400S4
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-
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- HY-101400S1
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dCTP-15N3,d14 dilithium; 2′-deoxycytidine-5′-triphosphate-15N3,d14 dilithium
|
Isotope-Labeled Compounds
Nucleoside Antimetabolite/Analog
DNA/RNA Synthesis
Endogenous Metabolite
|
Metabolic Disease
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Deoxycytidine triphosphate- 15N3,d14 (dCTP- 15N3,d14 dilithium; 2′-Deoxycytidine-5′-triphosphate- 15N3,d14) dilithium is deuterium and 15N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
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- HY-101400S2
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dCTP-13C9,15N3 dilithium; 2′-deoxycytidine-5′-triphosphate-13C9,15N3 dilithium
|
Isotope-Labeled Compounds
Nucleoside Antimetabolite/Analog
DNA/RNA Synthesis
Endogenous Metabolite
|
Metabolic Disease
|
Deoxycytidine triphosphate- 13C9, 15N3 (dCTP- 13C9, 15N3 dilithium; 2′-Deoxycytidine-5′-triphosphate- 13C9, 15N3) dilithium is 13C and 15N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
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- HY-W010771A
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dCTP trisodium,100 mM Solution,PCR Grade; 2′-deoxycytidine-5′-triphosphate trisodium,100 mM Solution,PCR Grade
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Biochemical Assay Reagents
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Others
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Deoxycytidine triphosphate trisodium,100 mM Solution,PCR Grade (dCTP trisodium,100 mM Solution,PCR Grade) is one of the raw materials used by DNA polymerase to synthesize long DNA chains during DNA replication. This product is provided in the form of aqueous solution .
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- HY-17564R
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2'-deoxycytidine monohydrochloride (Standard); deoxycytidine hydrochloride (Standard); NSC 83251 (Standard)
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Reference Standards
Endogenous Metabolite
Nucleoside Antimetabolite/Analog
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Others
Cancer
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2'-Deoxycytidine (hydrochloride) (Standard) is an analytical standard for 2'-Deoxycytidine (hydrochloride). This product is intended for research and analytical applications. 2'-Deoxycytidine hydrochloride is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
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- HY-17564
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-
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- HY-D0184
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deoxycytidine; Cytosine deoxyriboside; Deoxyribose cytidine
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Endogenous Metabolite
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Cancer
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2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer [2].
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- HY-W338294
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deoxycytidine hydrate; Cytosine deoxyriboside hydrate; Deoxyribose cytidine hydrate
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Nucleoside Antimetabolite/Analog
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Others
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2'-Deoxycytidine (Deoxycytidine) hydrate is a building block of nucleic acid .
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- HY-W338294S
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- HY-W654136
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deoxycytidine-13C; Cytosine deoxyriboside-13C; Deoxyribose cytidine-13C
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Isotope-Labeled Compounds
Endogenous Metabolite
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Cancer
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2'-Deoxycytidine-2'- 13C is 13C labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer [2] .
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- HY-W338294S1
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- HY-D0184S2
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deoxycytidine-15N3; Cytosine deoxyriboside-15N3; Deoxyribose cytidine-15N3
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Endogenous Metabolite
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Others
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2'-Deoxycytidine- 15N3 is the 15N labeled 2'-Deoxycytidine . 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu) [2].
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- HY-W338294S3
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deoxycytidine-d2 monohydrate; Cytosine deoxyriboside-d2 monohydrate; Deoxyribose cytidine-d2 monohydrate
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Isotope-Labeled Compounds
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Others
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2'-Deoxycytidine-d2 monohydrate is the deuterium labeled 2'-Deoxycytidine monohydrate .
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- HY-D0184S4
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deoxycytidine-d13; Cytosine deoxyriboside-d13; Deoxyribose cytidine-d13
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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2'-Deoxycytidine-d13 (Deoxycytidine-d13; Cytosine deoxyriboside-d13; Deoxyribose cytidine-d13) is deuterium labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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- HY-D0184S5
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deoxycytidine-13C9; Cytosine deoxyriboside-13C9; Deoxyribose cytidine-13C9
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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2'-Deoxycytidine- 13C9 (Deoxycytidine- 13C9; Cytosine deoxyriboside- 13C9; Deoxyribose cytidine- 13C9) is 13C-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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- HY-D0184S6
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deoxycytidine-13C,15N3; Cytosine deoxyriboside-13C,15N3; Deoxyribose cytidine-13C,15N3
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Isotope-Labeled Compounds
Endogenous Metabolite
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Cancer
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2'-Deoxycytidine- 13C, 15N3 (Deoxycytidine- 13C, 15N3) is 13C and 15N labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer [2].
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- HY-D0184S3
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deoxycytidine-13C9,15N3; Cytosine deoxyriboside-13C9,15N3; Deoxyribose cytidine-13C9,15N3
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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2'-Deoxycytidine- 13C9, 15N3 (Deoxycytidine- 13C9, 15N3; Cytosine deoxyriboside- 13C9, 15N3; Deoxyribose cytidine- 13C9, 15N3) is 13C and 15N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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- HY-14920
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Reverset; d-d4FC
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Reverse Transcriptase
HIV
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Infection
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Dexelvucitabine (Reverset; d-d4FC), a Cytidine (HY-B0158) analog, is an orally active nucleoside reverse transcriptase inhibitor. Dexelvucitabine is a powerful agent against HIV-1-resistant viruses containing a thymidine analog and/or M184V mutation in the viral polymerase. Dexelvucitabine is a 2′-Deoxycytidine antiretroviral agent .
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- HY-W009216
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5'-dCMP; Deoxy-CMP; 2'-deoxycytidine-5'-monophosphoric acid
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Endogenous Metabolite
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Metabolic Disease
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2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite. 2'-Deoxycytidine-5'-monophosphate is a deoxynucleotide building block of which DNA is made. 2'-Deoxycytidine-5'-monophosphate can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP and supports DNA biosynthesis .
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- HY-W011376
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Biochemical Assay Reagents
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Others
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5-Bromo-2'-deoxycytidine is a DNA photosensitizer. 5-Bromo-2'-deoxycytidine modifies the double-stranded DNA, and determinate the DNA damage 300 nm photon .
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- HY-14920R
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Reverse Transcriptase
HIV
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Infection
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Dexelvucitabine (Standard) is the analytical standard of Dexelvucitabine. This product is intended for research and analytical applications. Dexelvucitabine (Reverset; d-d4FC), a Cytidine (HY-B0158) analog, is an orally active nucleoside reverse transcriptase inhibitor. Dexelvucitabine is a powerful agent against HIV-1-resistant viruses containing a thymidine analog and/or M184V mutation in the viral polymerase. Dexelvucitabine is a 2′-Deoxycytidine antiretroviral agent .
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- HY-161080
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Nucleoside Antimetabolite/Analog
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Cancer
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4'-Ethynyl-2'-deoxycytidine is an anticancer nucleoside. 4'-Ethynyl-2'-deoxycytidine can used in study acute lymphoblastic leukemia and diffuse large B-cell lymphoma .
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- HY-W009216R
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5'-dCMP (Standard); Deoxy-CMP (Standard); 2'-deoxycytidine-5'-monophosphoric acid (Standard)
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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2'-Deoxycytidine-5'-monophosphoric acid (Standard) is the analytical standard of 2'-Deoxycytidine-5'-monophosphoric acid. This product is intended for research and analytical applications. 2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite. 2'-Deoxycytidine-5'-monophosphate is a deoxynucleotide building block of which DNA is made. 2'-Deoxycytidine-5'-monophosphate can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP and supports DNA biosynthesis .
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- HY-116217R
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DNA Methyltransferase
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Cancer
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5-Fluoro-2'-deoxycytidine (Standard) is the analytical standard of 5-Fluoro-2'-deoxycytidine. This product is intended for research and analytical applications. 5-Fluoro-2'-deoxycytidine (FdCyd), a fluoropyrimidine nucleoside analogue, is a DNA methyltransferase (DNMT) inhibitor. 5-Fluoro-2'-deoxycytidine is a tumor-selective proagent of thymidylate synthase inhibitor 5-fluoro-2′-dUMP. 5-Fluoro-2'-deoxycytidine can induce cell cycle arrest in tumor cells through the DNA damage response, and it has anti-tumor activity [2] .
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- HY-131394
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5hmdC
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Drug Derivative
DNA/RNA Synthesis
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Cancer
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5-Hydroxymethyl-2’-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2’-deoxycytidine may serve as a marker of irreversibly damaged cells [2].
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- HY-129861
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HSV
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Infection
Cancer
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5'-Ethynyl-2'-deoxycytidine is an inhibitor for HSV, that inhibits the cytopathic effect of HSV-1 in primary rabbit kidney cell with a MIC of 0.2 μg/mL. 5'-Ethynyl-2'-deoxycytidine inhibits the proliferation of leukemia L1210 cell with an IC50 of 64.5 μg/mL .
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- HY-173258
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- HY-152448
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Nucleoside Antimetabolite/Analog
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Others
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2’-Azido-2’-deoxycytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2’-Azido-2’-deoxycytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. 2’-Azido-2’-deoxycytidine is an azidonucleoside,and it should be phosphorylated twice to become an inhibitor of the nucleotide reductase.
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- HY-160428
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- HY-W130204
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N4-Acetyl-2'-deoxycytidine
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Nucleoside Antimetabolite/Analog
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Cancer
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N-Acetyl-2′-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W012078
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5-Methyldeoxycytidine
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DNA Methyltransferase
Endogenous Metabolite
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Others
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5-Methyl-2'-deoxycytidine (5mdC) is an endogenous substrate of DNA methyltransferases (such as mammalian 5-C-MTase) and binds to DNA dependent on the formation of DNA stem-loop structures. 5-Methyl-2'-deoxycytidine guides de novo DNA methylation by acting as a methylation mark and activates the methylation of adjacent CpG sites in single-stranded DNA through cis action. 5-Methyl-2'-deoxycytidine regulates DNA methylation patterns by recruiting methyltransferases to specific chromatin regions, affecting chromatin condensation and gene expression. Its distribution in plant cells is related to cell proliferation and differentiation stages. The methylation level of 5-Methyl-2'-deoxycytidine is low in proliferating cells and high in differentiated cells [2] .
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- HY-W010861
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- HY-116217
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FdCyd; NSC-48006
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DNA Methyltransferase
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Cancer
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5-Fluoro-2'-deoxycytidine (FdCyd), a fluoropyrimidine nucleoside analogue, is a DNA methyltransferase (DNMT) inhibitor. 5-Fluoro-2'-deoxycytidine is a tumor-selective proagent of thymidylate synthase inhibitor 5-fluoro-2′-dUMP. 5-Fluoro-2'-deoxycytidine can induce cell cycle arrest in tumor cells through the DNA damage response, and it has anti-tumor activity [2] .
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- HY-129057
-
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HCV
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Infection
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2',5-Difluoro-2'-deoxycytidine, compound 13, has potent anti-HCV activity and toxicity to ribosomal RNA (rRNA) .
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- HY-W011152
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dCMP disodium
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Endogenous Metabolite
|
Others
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2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) is an endogenous metabolite .
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-
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- HY-W009139
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Biochemical Assay Reagents
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Others
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N4-Benzoyl-2'-deoxycytidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-138593
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-
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- HY-130801
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5-OHdU
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Endogenous Metabolite
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Metabolic Disease
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5-Hydroxy-2'-deoxyuridine (5-OHdU) is a major stable oxidation product of 2'-Deoxycytidine. 5-Hydroxy-2'-deoxyuridine can be incorporated into DNA in vitro by DNA polymerase .
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- HY-101904
-
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Nucleoside Antimetabolite/Analog
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Others
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2-Chloro-2'-deoxycytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-152452
-
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Nucleoside Antimetabolite/Analog
|
Others
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2′-Amino-2′-deoxycytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W740027
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-
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- HY-W654228
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-
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- HY-W009216S3
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5'-dCMP-d12 dilithium; Deoxy-CMP-d12 dilithium; 2'-deoxycytidine-5'-monophosphoric acid-d12 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
2'-Deoxycytidine-5'-monophosphoric acid-d12 dilithium is deuterium labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
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- HY-154472
-
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Nucleoside Antimetabolite/Analog
|
Cancer
|
N4-Ethyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
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- HY-W009216S
-
5'-dCMP-15N3; Deoxy-CMP-15N3; 2'-deoxycytidine-5'-monophosphoric acid-15N3
|
Endogenous Metabolite
|
Metabolic Disease
|
2'-Deoxycytidine-5'-monophosphoric acid- 15N3 is the 15N labeled 2'-Deoxycytidine-5'-monophosphoric acid . 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
|
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- HY-139015
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5-Aza-T-dCyd; NTX-301
|
DNA Methyltransferase
|
Cancer
|
5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd) is an orally active DNA methyltransferase I (DNMT1) inhibitor. 5-Aza-4'-thio-2'-deoxycytidine, a sulfur-containing deoxy-cytidine analog, has the potential for DNA hypomethylating and has antitumor effects .
|
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- HY-W009216S2
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5'-dCMP-15N3,d12 dilithium; Deoxy-CMP-15N3,d12 dilithium; 2'-deoxycytidine-5'-monophosphoric acid-15N3,d12 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
2'-Deoxycytidine-5'-monophosphoric acid- 15N3,d12 dilithium is deuterium and 15N labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
|
-
- HY-154035
-
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Nucleoside Antimetabolite/Analog
|
Cancer
|
N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-113659
-
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Endogenous Metabolite
|
Infection
|
3',5'-O-Bis(isobutyryl)-4'-azido-2'-β-C-methyl-2'-deoxycytidine functions as an NS5B inhibitor of RNA polymerase, and is utilized in the treatment of HCV infection.
|
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- HY-W009216S1
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5'-dCMP-13C9,15N3 dilithium; Deoxy-CMP-13C9,15N3 dilithium; 2'-deoxycytidine-5'-monophosphoric acid-13C9,15N3 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
2'-Deoxycytidine-5'-monophosphoric acid- 13C9, 15N3 dilithium is 13C and 15N-labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
|
-
- HY-W010706
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5'-O-DMT-N4-Bz-dC
|
Nucleoside Antimetabolite/Analog
|
Others
|
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA .
|
-
- HY-154212
-
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Nucleoside Antimetabolite/Analog
|
Cancer
|
N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-D0184R
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deoxycytidine (Standard); Cytosine deoxyriboside (Standard); Deoxyribose cytidine (Standard)
|
Reference Standards
Endogenous Metabolite
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Cancer
|
Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate). This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections [2] .
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-
- HY-A0004S
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5-Aza-2'-deoxycytidine-13C5; 5-AZA-CdR-13C5; NSC 127716-13C5
|
Isotope-Labeled Compounds
DNA Methyltransferase
Nucleoside Antimetabolite/Analog
Apoptosis
|
Cancer
|
Decitabine- 13C5 (5-Aza-2'-deoxycytidine- 13C5) is 13C labeled Decitabine. Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity [2].
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-
- HY-W011138
-
-
- HY-131813
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2'-deoxycytidine-5'-O-monophosphorothioate
|
Drug Derivative
|
Others
|
5'-dCMPS is an analogue of 5'-dCMP and a potential substrate, competitive inhibitor or regulator of enzymes that interact with 5'-dCMP .
|
-
- HY-W784574A
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2'-deoxycytidine-5'-O-1-thiotriphosphate (sodium)
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Biochemical Assay Reagents
DNA/RNA Synthesis
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Others
|
dCTPαS sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
|
-
- HY-155867
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5-Iodo-2′-deoxycytidine 5′-triphosphate
|
DNA/RNA Synthesis
|
Others
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5-Iodo-dCTP is a good substrates for DNA polymerases and can be used for DNA synthesis.
|
-
- HY-155869
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5-Fluoro-2′-deoxycytidine 5′-triphosphate
|
DNA/RNA Synthesis
|
Others
|
5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .
|
-
- HY-155869A
-
5-Fluoro-2′-deoxycytidine 5′-triphosphate sodium
|
DNA/RNA Synthesis
|
Others
|
5-fluoro-dCTP sodium is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase .
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-
- HY-145972
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Cyanine 3-6-propargylamino-2'-deoxycytidine-5'-triphosphate
|
DNA/RNA Synthesis
|
Others
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Cyanine 3-dCTP is a Cy3-labeled nucleotide and can be used for DNA synthesis.
|
-
- HY-A0004
-
Decitabine
Maximum Cited Publications
111 Publications Verification
5-Aza-2'-deoxycytidine; 5-AZA-CdR; NSC 127716
|
DNA Methyltransferase
Apoptosis
Nucleoside Antimetabolite/Analog
|
Cancer
|
Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity [2].
|
-
- HY-A0004R
-
5-Aza-2'-deoxycytidine (Standard); 5-AZA-CdR (Standard); NSC 127716 (Standard)
|
Reference Standards
DNA Methyltransferase
Apoptosis
Nucleoside Antimetabolite/Analog
|
Cancer
|
Decitabine (Standard) is the analytical standard of Decitabine. This product is intended for research and analytical applications. Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity [2].
|
-
- HY-P5443
-
|
Bacterial
|
Others
|
Pyrrhocoricin is a biological active peptide. (Antimicrobial activity against Gram-negative bacteria)
|
-
- HY-17365
-
-
Cat. No. |
Product Name |
Type |
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- HY-W010771
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dCTP disodium; 2′-deoxycytidine-5′-triphosphate disodium
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Gene Sequencing and Synthesis
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Deoxycytidine triphosphate (disodium) (dCTP (disodium); 2′-Deoxycytidine-5′-triphosphate (disodium)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-101400
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dCTP; 2′-deoxycytidine-5′-triphosphate
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Gene Sequencing and Synthesis
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Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing [2] .
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- HY-101400A
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dCTP (trisodium) solution (100mM); 2′-deoxycytidine-5′-triphosphate (trisodium) solution (100mM)
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Gene Sequencing and Synthesis
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Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing [2] .
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- HY-W011376
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Biochemical Assay Reagents
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5-Bromo-2'-deoxycytidine is a DNA photosensitizer. 5-Bromo-2'-deoxycytidine modifies the double-stranded DNA, and determinate the DNA damage 300 nm photon .
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- HY-W011152
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- HY-W011138
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- HY-W010771A
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dCTP trisodium,100 mM Solution,PCR Grade; 2′-deoxycytidine-5′-triphosphate trisodium,100 mM Solution,PCR Grade
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Cell Assay Reagents
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Deoxycytidine triphosphate trisodium,100 mM Solution,PCR Grade (dCTP trisodium,100 mM Solution,PCR Grade) is one of the raw materials used by DNA polymerase to synthesize long DNA chains during DNA replication. This product is provided in the form of aqueous solution .
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- HY-W784574A
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2'-deoxycytidine-5'-O-1-thiotriphosphate (sodium)
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Gene Sequencing and Synthesis
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dCTPαS sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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Category |
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Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-101400S
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Deoxycytidine triphosphate-d14 (dCTP-d14 dilithium; 2′-Deoxycytidine-5′-triphosphate-d14) dilithium is deuterium labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
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- HY-101400S3
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Deoxycytidine triphosphate- 15N3 (dCTP- 15N3 dilithium; 2′-Deoxycytidine-5′-triphosphate- 15N3) dilithium is 15N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
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- HY-W654136
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2'-Deoxycytidine-2'- 13C is 13C labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer [2] .
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- HY-D0184S2
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2'-Deoxycytidine- 15N3 is the 15N labeled 2'-Deoxycytidine . 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu) [2].
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- HY-101400S4
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Deoxycytidine triphosphate- 13C9 (dCTP- 13C9 dilithium; 2′-Deoxycytidine-5′-triphosphate- 13C9) dilithium is 13C-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
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- HY-101400S1
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Deoxycytidine triphosphate- 15N3,d14 (dCTP- 15N3,d14 dilithium; 2′-Deoxycytidine-5′-triphosphate- 15N3,d14) dilithium is deuterium and 15N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
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- HY-101400S2
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Deoxycytidine triphosphate- 13C9, 15N3 (dCTP- 13C9, 15N3 dilithium; 2′-Deoxycytidine-5′-triphosphate- 13C9, 15N3) dilithium is 13C and 15N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
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- HY-W338294S
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2'-Deoxycytidine- 13C (monohydrate) is the 13C labeled 2'-Deoxycytidine .
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- HY-W338294S1
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2'-Deoxycytidine- 13C-2 (monohydrate) Monohydrate is the 13C labeled 2'-Deoxycytidine .
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- HY-W338294S3
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2'-Deoxycytidine-d2 monohydrate is the deuterium labeled 2'-Deoxycytidine monohydrate .
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- HY-D0184S4
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2'-Deoxycytidine-d13 (Deoxycytidine-d13; Cytosine deoxyriboside-d13; Deoxyribose cytidine-d13) is deuterium labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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- HY-D0184S5
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2'-Deoxycytidine- 13C9 (Deoxycytidine- 13C9; Cytosine deoxyriboside- 13C9; Deoxyribose cytidine- 13C9) is 13C-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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- HY-D0184S6
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2'-Deoxycytidine- 13C, 15N3 (Deoxycytidine- 13C, 15N3) is 13C and 15N labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer [2].
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- HY-D0184S3
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2'-Deoxycytidine- 13C9, 15N3 (Deoxycytidine- 13C9, 15N3; Cytosine deoxyriboside- 13C9, 15N3; Deoxyribose cytidine- 13C9, 15N3) is 13C and 15N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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- HY-W740027
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5-Methyl-2'-deoxycytidine-d3 is the deuterium labeled Methyl-2'-deoxycytidine .
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- HY-W654228
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5-Hydroxymethyl-2'-deoxycytidine-d3 is the deuterium labeled 5-Hydroxymethyl-2'-deoxycytidine .
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- HY-W009216S3
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2'-Deoxycytidine-5'-monophosphoric acid-d12 dilithium is deuterium labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
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- HY-W009216S
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2'-Deoxycytidine-5'-monophosphoric acid- 15N3 is the 15N labeled 2'-Deoxycytidine-5'-monophosphoric acid . 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
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- HY-W009216S2
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2'-Deoxycytidine-5'-monophosphoric acid- 15N3,d12 dilithium is deuterium and 15N labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
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- HY-W009216S1
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2'-Deoxycytidine-5'-monophosphoric acid- 13C9, 15N3 dilithium is 13C and 15N-labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
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- HY-A0004S
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Decitabine- 13C5 (5-Aza-2'-deoxycytidine- 13C5) is 13C labeled Decitabine. Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity [2].
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Classification |
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- HY-129861
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Alkynes
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5'-Ethynyl-2'-deoxycytidine is an inhibitor for HSV, that inhibits the cytopathic effect of HSV-1 in primary rabbit kidney cell with a MIC of 0.2 μg/mL. 5'-Ethynyl-2'-deoxycytidine inhibits the proliferation of leukemia L1210 cell with an IC50 of 64.5 μg/mL .
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- HY-152448
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Azide
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2’-Azido-2’-deoxycytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2’-Azido-2’-deoxycytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. 2’-Azido-2’-deoxycytidine is an azidonucleoside,and it should be phosphorylated twice to become an inhibitor of the nucleotide reductase.
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Classification |
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- HY-W010771
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dCTP disodium; 2′-deoxycytidine-5′-triphosphate disodium
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Nucleotides and their Analogs
C
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Deoxycytidine triphosphate (disodium) (dCTP (disodium); 2′-Deoxycytidine-5′-triphosphate (disodium)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-101400
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dCTP; 2′-deoxycytidine-5′-triphosphate
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Nucleotides and their Analogs
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Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing [2] .
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- HY-101400A
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dCTP (trisodium) solution (100mM); 2′-deoxycytidine-5′-triphosphate (trisodium) solution (100mM)
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Nucleotides and their Analogs
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Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing [2] .
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- HY-17564
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2'-deoxycytidine monohydrochloride; deoxycytidine hydrochloride; NSC 83251
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Nucleosides and their Analogs
C
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2'-Deoxycytidine hydrochloride is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
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- HY-D0184
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deoxycytidine; Cytosine deoxyriboside; Deoxyribose cytidine
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Nucleosides and their Analogs
C
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2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer [2].
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- HY-W009216
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5'-dCMP; Deoxy-CMP; 2'-deoxycytidine-5'-monophosphoric acid
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Nucleosides and their Analogs
C
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2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite. 2'-Deoxycytidine-5'-monophosphate is a deoxynucleotide building block of which DNA is made. 2'-Deoxycytidine-5'-monophosphate can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP and supports DNA biosynthesis .
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- HY-W011376
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Nucleosides and their Analogs
C
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5-Bromo-2'-deoxycytidine is a DNA photosensitizer. 5-Bromo-2'-deoxycytidine modifies the double-stranded DNA, and determinate the DNA damage 300 nm photon .
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- HY-131394
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5hmdC
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Nucleosides and their Analogs
C
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5-Hydroxymethyl-2’-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2’-deoxycytidine may serve as a marker of irreversibly damaged cells [2].
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- HY-173258
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- HY-161080
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Nucleosides and their Analogs
C
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4'-Ethynyl-2'-deoxycytidine is an anticancer nucleoside. 4'-Ethynyl-2'-deoxycytidine can used in study acute lymphoblastic leukemia and diffuse large B-cell lymphoma .
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- HY-152448
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Nucleosides and their Analogs
C
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2’-Azido-2’-deoxycytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2’-Azido-2’-deoxycytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. 2’-Azido-2’-deoxycytidine is an azidonucleoside,and it should be phosphorylated twice to become an inhibitor of the nucleotide reductase.
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- HY-160428
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Nucleoside Phosphoramidites
C
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DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite (compound 1B) is a phosphoramidite of 5-Fluoro-2'-deoxycytidine .
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- HY-W130204
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N4-Acetyl-2'-deoxycytidine
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Nucleosides and their Analogs
C
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N-Acetyl-2′-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W010861
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- HY-W011152
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- HY-W009139
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Nucleosides and their Analogs
C
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N4-Benzoyl-2'-deoxycytidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-138593
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Nucleosides and their Analogs
C
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5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside. 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
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- HY-101904
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Nucleosides and their Analogs
C
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2-Chloro-2'-deoxycytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-152452
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Nucleosides and their Analogs
C
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2′-Amino-2′-deoxycytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154472
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Nucleosides and their Analogs
C
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N4-Ethyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-154035
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Nucleosides and their Analogs
C
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N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-113659
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Nucleosides and their Analogs
C
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3',5'-O-Bis(isobutyryl)-4'-azido-2'-β-C-methyl-2'-deoxycytidine functions as an NS5B inhibitor of RNA polymerase, and is utilized in the treatment of HCV infection.
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- HY-W010706
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5'-O-DMT-N4-Bz-dC
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Nucleosides and their Analogs
C
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N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA .
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- HY-154212
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Nucleosides and their Analogs
C
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N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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