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1,3-Diamino-2-hydroxypropane-N,N,N′,N′-tetraacetic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (12) ADC Cytotoxin (1) Amyloid-β (1) Antibiotic (1) ATF6 (1) Bacterial (4) Biochemical Assay Reagents (22) CD38 (1) CGRP Receptor (2) DNA/RNA Synthesis (1) Drug Derivative (1) Endogenous Metabolite (7) Ephrin Receptor (1) Ferroportin (1) Fluorescent Dye (5) Fungal (1) GCGR (5) GLP Receptor (6) GnRH Receptor (1) Isotope-Labeled Compounds (1) Liposome (1) MARCKS (2) Melanocortin Receptor (1) Natriuretic Peptide Receptor (NPR) (1) NO Synthase (2) NOD-like Receptor (NLR) (1) Nucleoside Antimetabolite/Analog (2) Oxytocin Receptor (1) Parasite (2) PD-1/PD-L1 (2) Peptide-Drug Conjugates (PDCs) (1) Phospholipase (2) Phytohormone (1) PKC (2) Potassium Channel (1) Reference Standards (1) Renin (1) Somatostatin Receptor (2) Topoisomerase (1) Vasopressin Receptor (3)
By Research Areas:	Cancer (16) Cardiovascular Disease (2) Endocrinology (4) Infection (5) Inflammation/Immunology (9) Metabolic Disease (14) Neurological Disease (8)
Oligonucleotides:	Nucleosides and their Analogs (2) Cationic Lipids (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

*2,4-Diamino-6-hydroxypyrimidine* 1 Publications Verification	NO Synthase	Inflammation/Immunology
2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis). 2,4-Diamino-6-hydroxypyrimidine blocks Tetrahydrobiopterin (BH4) synthesis and suppresses NO production .

*3,8-Diamino-6-phenylphenanthridine*	Biochemical Assay Reagents	Others
3,8-Diamino-6-phenylphenanthridine can bind to DNA by means of a non-specific binding along the DNA exterior .

*5,6-Diamino-1,10-phenanthroline*	Biochemical Assay Reagents	Others
5,6-Diamino-1,10-phenanthroline can be used as ligands for metal ions for drug synthesis .

*2-Hydroxypropane-1,3-diyl distearate-d75*	Isotope-Labeled Compounds	Others
2-Hydroxypropane-1,3-diyl distearate-d₇₅ is deuterium labeled Glyceryl 1,3-distearate .

*(S)-3-Hydroxypropane-1,2-diyl dioctanoate* 1,2-Dioctanoyl-sn-glycerol	Endogenous Metabolite	Others
(S)-3-Hydroxypropane-1,2-diyl dioctanoate (1,2-Dioctanoyl-sn-glycerol) is a cell-permeable analog of the PKC-activating second messenger DAG. (S)-3-Hydroxypropane-1,2-diyl dioctanoate induces acrosome reaction in human sperm.

*2,4-Diamino-6-hydroxypyrimidine (Standard)*	Reference Standards NO Synthase	Inflammation/Immunology
2,4-Diamino-6-hydroxypyrimidine (Standard) is the analytical standard of 2,4-Diamino-6-hydroxypyrimidine. This product is intended for research and analytical applications. 2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis). 2,4-Diamino-6-hydroxypyrimidine blocks Tetrahydrobiopterin (BH4) synthesis and suppresses NO production .

Diamino lipid DAL4	Liposome	Cancer
Diamino lipid DAL4 is diamino lipid for the preparation of lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12, IL-27 and GM-CSF. Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity .

*1,2-Diamino-3,4-ethylenedioxybenzene*	Fluorescent Dye	Others
1,2-Diamino-3,4-ethylenedioxybenzene is a carbonyl-reactive fluorometric labeling agent.

*[S-Methanethiosulfonylcysteaminyl]ethylenediamine-N,N,N',N'-tetraacetic* acid**	Biochemical Assay Reagents	Others
[S-Methanethiosulfonylcysteaminyl]ethylenediamine-N,N,N',N'-tetraacetic acid is a biochemical assay reagent.

*3,6-Diamino-9(10H)-acridone*	Topoisomerase	Others
3,6-Diamino-9(10H)-acridone is a topoisomerase inhibitor .

*1,2-Diamino-4,5-dimethoxybenzene hydrochloride*	Biochemical Assay Reagents	Others
1,2-Diamino-4,5-dimethoxybenzene hydrochloride is an aromatic diamine that reacts with aldehydes to produce highly fluorescent benzimidazole derivatives.

*5-Bromo-2,4-diamino-6-hydroxypyrimidine*	Biochemical Assay Reagents
5-Bromo-2,4-diamino-6-hydroxypyrimidine is a kind of biochemical reagent.

*Tetraacetoxymethyl bis(2-aminoethyl) ether N,N,N',N'-tetraacetic* acid**	Biochemical Assay Reagents	Others
Tetraacetoxymethyl bis(2-aminoethyl) ether N,N,N',N'-tetraacetic acid is a biochemical reagent.

*Ethylenediamine-N,N,N,N-tetraacetic* Acid Tetraethyl Ester** Tetraethyl ethylenediaminetetraacetate	Biochemical Assay Reagents	Others
Ethylenediamine-N,N,N,N-tetraacetic Acid Tetraethyl Ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

*1,3-Diaminopropane-N,N,N',N'-tetraacetic* acid** 1,3-DAPTA	Biochemical Assay Reagents
1,3-Diaminopropane-N,N,N',N'-tetraacetic acid (1,3-DAPTA) is a kind of biochemical reagent.

Reinecke Diamino-tetraisothiocyanato-chromium	Biochemical Assay Reagents	Others
Reinecke (Diamino-tetraisothiocyanato-chromium) is an ammonium salt. Reinecke participates in the quantitative precipitation of histones and basic compounds present in acidic tissue extracts by forming Reinecke complexes .

*N-(2,6-Diamino-6-hydroxymethylpimelyl)-L-alanine*	Bacterial	Infection
N-(2,6-Diamino-6-hydroxymethylpimelyl)-L-alanine shows anti-Escherichia coli activity, and is combined with several cell wall synthesis inhibitors such as Fosfomycin, Cycloserine, Penicillin, and Cephalosporin, the combination of sporozoin has obvious synergistic antibacterial effect .

mcK6A1	Amyloid-β	Neurological Disease
mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .

*5,6-Diamino-N,N,N',N'-tetraethyl-rhodamin*	Fluorescent Dye	Others
5,6-Diamino-N,N,N',N'-tetraethyl-rhodamin is a fluorescent indicator for NO .

*1,8-Diamino-4,5-dihydroxyanthraquinone*	Fluorescent Dye	Others
1,8-Diamino-4,5-dihydroxyanthraquinone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

*4,4'-Diamino-1,1'-iminodianthraquinone*	Fluorescent Dye	Others
4,4'-Diamino-1,1'-iminodianthraquinone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

(NH2)2bpy 4,4'-Diamino-2,2'-bipyridine	Biochemical Assay Reagents	Others
(NH2)2bpy (4,4'-Diamino-2,2'-bipyridine) is an organic compound commonly used as a catalyst and complexing reagent. It can form complexes with other metal ions or organic molecules, and can play a catalytic role in some organic synthesis reactions. In addition, this compound is also widely used in some chemical analysis and detection methods, such as in biological analysis and electrochemical analysis

ZP3022	GCGR	Metabolic Disease
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .

DSPE-DOTA sodium 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt	Biochemical Assay Reagents	Neurological Disease Inflammation/Immunology Cancer
DSPE-DOTA sodium (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt) is a chelating lipid used as a key contrast agent in magnetic resonance imaging (MRI). DSPE-DOTA sodium can be used for imaging detection of tumors, neurological and inflammatory diseases .

*4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine*	Nucleoside Antimetabolite/Analog	Others
4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

*2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine*	Nucleoside Antimetabolite/Analog	Others
2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

*4,5-Diamino-N,N,N',N'-tetraethyl-rhodamin*	Fluorescent Dye	Others
4,5-Diamino-N,N,N',N'-tetraethyl-rhodamin is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

F992 TFA	Vasopressin Receptor	Neurological Disease
F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

F992	Vasopressin Receptor	Neurological Disease
F992 is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

MANS peptide TFA	MARCKS PKC	Inflammation/Immunology Cancer
MANS peptide TFA is the TFA salt form of MANS peptide (HY-P10218). MANS peptide TFA is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .

MANS peptide	MARCKS PKC	Inflammation/Immunology Cancer
MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .

D-Asparagine monohydrate	Biochemical Assay Reagents	Others
(R)-2,4-diamino-4-oxobutanoic acid hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

dCNP	Natriuretic Peptide Receptor (NPR)	Inflammation/Immunology Cancer
dCNP binds to NPR-B/C receptor, activates cGMP signaling pathway, and regulates vascular function. dCNP exhibits anti-hypoxia property through downregulation of hypoxia-related genes expressions like HIF1α and HIF2α. dCNP inhibits the induction of tumor stroma and exhibits anti-fibrosis activity. dCNP upregulates CTLs, NK cells, and conventional type 1 dendritic cells in tumors, and activates immune responses .

CP7-FP13-2	Bacterial	Infection
CP7-FP13-2 is a peptide with antivirulence factor and antibacterial activity. CP7-FP13-2 inhibits the formation of Staphylococcus aureus biofilm and has good antibacterial efficacy in mice .

SHR-2042	GLP Receptor	Endocrinology
SHR-2042 is a selective agonist of the GLP-1 receptor.SHR-2042 improves glycemic control by activating the GLP-1 receptor, enhancing insulin secretion and inhibiting glucagon secretion. SHR-2042 combined with sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC) promotes monomerization through the formation of micelles and improves oral absorption efficiency .

Cagrilintide acetate 3 Publications Verification	CGRP Receptor	Metabolic Disease
Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity studies .

FC382K10W15	GLP Receptor GCGR	Metabolic Disease
FC382K10W15 is a glucagon analogue and GLP-1R/GCGR agonist. FC382K10W15 can be used in type 2 diabetes research .

FC382K10W15 TFA	GLP Receptor GCGR	Metabolic Disease
FC382K10W15 TFA is a glucagon analogue and GLP-1R/GCGR agonist. FC382K10W15 TFA can be used in type 2 diabetes research .

Cagrilintide 3 Publications Verification	CGRP Receptor	Metabolic Disease
Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity .

BMSpep-57	PD-1/PD-L1	Cancer
BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC₅₀ of 7.68 nM. BMSpep-57 binds to PD-L1 with K_ds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .

BMSpep-57 hydrochloride	PD-1/PD-L1	Cancer
BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC₅₀ of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with K_ds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .

RG7697	GLP Receptor	Metabolic Disease
RG7697 is a dual agonist for glucagon-like peptide receptor (GLP Receptor) and glucosedependent insulinotropic polypeptide receptor (GIPR), with EC₅₀ of 5 and 3 pM, respectively. RG7697 exhibits antihyperglycemic property .

Plipastatin B1	Antibiotic Fungal Phospholipase	Infection
Plipastatin B1 is a lipopeptide antibiotic, an inhibitor of phospholipase A₂ (PLA2), which has antifungal activity .

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin SKF 100273	Vasopressin Receptor	Metabolic Disease
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist .

Survodutide BI 456906	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

Survodutide TFA BI 456906 TFA	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

Cat. No.	Product Name	Type

HY-W324406

*1,2-Diamino-3,4-ethylenedioxybenzene*	Fluorescent Dyes/Probes
1,2-Diamino-3,4-ethylenedioxybenzene is a carbonyl-reactive fluorometric labeling agent.

HY-D0081A

*5,6-Diamino-N,N,N',N'-tetraethyl-rhodamin*	Fluorescent Dyes/Probes
5,6-Diamino-N,N,N',N'-tetraethyl-rhodamin is a fluorescent indicator for NO .

HY-D0299

1,8-Diamino-4,5-dihydroxyanthraquinone

Dyes

1,8-Diamino-4,5-dihydroxyanthraquinone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D0298

4,4'-Diamino-1,1'-iminodianthraquinone

Dyes

4,4'-Diamino-1,1'-iminodianthraquinone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D0081

4,5-Diamino-N,N,N',N'-tetraethyl-rhodamin

Fluorescent Dyes/Probes

4,5-Diamino-N,N,N',N'-tetraethyl-rhodamin is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

Cat. No.	Product Name	Type

HY-W011511

*3,8-Diamino-6-phenylphenanthridine*	Cell Assay Reagents
3,8-Diamino-6-phenylphenanthridine can bind to DNA by means of a non-specific binding along the DNA exterior .

HY-W128312

*1,3-Diaminopropane-N,N,N',N'-tetraacetic* acid** 1,3-DAPTA	Chelators
1,3-Diaminopropane-N,N,N',N'-tetraacetic acid (1,3-DAPTA) is a kind of biochemical reagent.

HY-W004547

(NH2)2bpy

4,4'-Diamino-2,2'-bipyridine

Biochemical Assay Reagents

(NH2)2bpy (4,4'-Diamino-2,2'-bipyridine) is an organic compound commonly used as a catalyst and complexing reagent. It can form complexes with other metal ions or organic molecules, and can play a catalytic role in some organic synthesis reactions. In addition, this compound is also widely used in some chemical analysis and detection methods, such as in biological analysis and electrochemical analysis

HY-151508

Diamino lipid DAL4	Drug Delivery
Diamino lipid DAL4 is diamino lipid for the preparation of lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12, IL-27 and GM-CSF. Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity .

HY-W127798

*[S-Methanethiosulfonylcysteaminyl]ethylenediamine-N,N,N',N'-tetraacetic* acid**	Chelators
[S-Methanethiosulfonylcysteaminyl]ethylenediamine-N,N,N',N'-tetraacetic acid is a biochemical assay reagent.

HY-W012467

*5-Bromo-2,4-diamino-6-hydroxypyrimidine*	Gene Sequencing and Synthesis
5-Bromo-2,4-diamino-6-hydroxypyrimidine is a kind of biochemical reagent.

HY-W127804

*Tetraacetoxymethyl bis(2-aminoethyl) ether N,N,N',N'-tetraacetic* acid**	Chelators
Tetraacetoxymethyl bis(2-aminoethyl) ether N,N,N',N'-tetraacetic acid is a biochemical reagent.

HY-W127811

*Ethylenediamine-N,N,N,N-tetraacetic* Acid Tetraethyl Ester** Tetraethyl ethylenediaminetetraacetate	Biochemical Assay Reagents
Ethylenediamine-N,N,N,N-tetraacetic Acid Tetraethyl Ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W034869

Reinecke Diamino-tetraisothiocyanato-chromium	Cell Assay Reagents
Reinecke (Diamino-tetraisothiocyanato-chromium) is an ammonium salt. Reinecke participates in the quantitative precipitation of histones and basic compounds present in acidic tissue extracts by forming Reinecke complexes .

HY-173384

DSPE-DOTA sodium 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt	Drug Delivery
DSPE-DOTA sodium (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt) is a chelating lipid used as a key contrast agent in magnetic resonance imaging (MRI). DSPE-DOTA sodium can be used for imaging detection of tumors, neurological and inflammatory diseases .

HY-W017444

D-Asparagine monohydrate	Cell Assay Reagents Amino acids and Derivatives
(R)-2,4-diamino-4-oxobutanoic acid hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W013178

DCTA monohydrate

Indicators

DCTA monohydrate is an organic acid. DCTA refers to N,N,N',N' -tetraacetic acid, which has a strong chelating ability. DCTA monohydrate can be used as a chelating agent and coordination reagent for metal ions. DCTA monohydrate, for example, forms stable complexes with many metal ions, including calcium, magnesium and zinc. DCTA modified with ethylene glycol is selective to calcium ions in the presence of magnesium ions .

HY-173383

DOPE-DOTA sodium 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt	Drug Delivery
DOPE-DOTA sodium is a chelated lipid that serves as a key contrast agent in magnetic resonance imaging (MRI). DOPE-DOTA sodium can be used for cancer, blood-brain barrier disruption, abnormalities such as aneurysms or plaque buildup, inflammation in arthritis, and liver function and lesions study

HY-W007978A

(S)-[1,1'-Binaphthalene]-2,2'-diamine S-(-)-2,2-Diamino-1,1-binaphthyl	Biochemical Assay Reagents
(S)-[1,1'-Binaphthalene]-2,2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Target	Research Area

HY-P0041A

F992 TFA	Vasopressin Receptor	Neurological Disease
F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

HY-P10218A

MANS peptide TFA	MARCKS PKC	Inflammation/Immunology Cancer
MANS peptide TFA is the TFA salt form of MANS peptide (HY-P10218). MANS peptide TFA is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .

HY-P10218

MANS peptide	MARCKS PKC	Inflammation/Immunology Cancer
MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .

HY-W017444

D-Asparagine monohydrate	Biochemical Assay Reagents	Others
(R)-2,4-diamino-4-oxobutanoic acid hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P10869

dCNP	Natriuretic Peptide Receptor (NPR)	Inflammation/Immunology Cancer
dCNP binds to NPR-B/C receptor, activates cGMP signaling pathway, and regulates vascular function. dCNP exhibits anti-hypoxia property through downregulation of hypoxia-related genes expressions like HIF1α and HIF2α. dCNP inhibits the induction of tumor stroma and exhibits anti-fibrosis activity. dCNP upregulates CTLs, NK cells, and conventional type 1 dendritic cells in tumors, and activates immune responses .

HY-P10381

palm11-TTDS-PrRP31	Peptides	Others
palm11-TTDS-PrRP31 is a strong agonist of GPR10 (EC₅₀: 84 pM). palm11-TTDS-PrRP31 has long-lasting anorexigenic effects .

HY-P10876

mcK6A1	Amyloid-β	Neurological Disease
mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .

HY-P10341

ZP3022	GCGR	Metabolic Disease
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .

HY-P0041

F992	Vasopressin Receptor	Neurological Disease
F992 is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

HY-P4837

Ac-Lys-D-Ala-D-lactic acid	Peptides	Others
Ac-Lys-D-Ala-D-lactic acid is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P10200

CP7-FP13-2	Bacterial	Infection
CP7-FP13-2 is a peptide with antivirulence factor and antibacterial activity. CP7-FP13-2 inhibits the formation of Staphylococcus aureus biofilm and has good antibacterial efficacy in mice .

HY-P10318

SHR-2042	GLP Receptor	Endocrinology
SHR-2042 is a selective agonist of the GLP-1 receptor.SHR-2042 improves glycemic control by activating the GLP-1 receptor, enhancing insulin secretion and inhibiting glucagon secretion. SHR-2042 combined with sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC) promotes monomerization through the formation of micelles and improves oral absorption efficiency .

HY-P3462A

Cagrilintide acetate 3 Publications Verification	CGRP Receptor	Metabolic Disease
Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity studies .

HY-P5161

FC382K10W15	GLP Receptor GCGR	Metabolic Disease
FC382K10W15 is a glucagon analogue and GLP-1R/GCGR agonist. FC382K10W15 can be used in type 2 diabetes research .

HY-P5161A

FC382K10W15 TFA	GLP Receptor GCGR	Metabolic Disease
FC382K10W15 TFA is a glucagon analogue and GLP-1R/GCGR agonist. FC382K10W15 TFA can be used in type 2 diabetes research .

HY-P3462

Cagrilintide 3 Publications Verification	CGRP Receptor	Metabolic Disease
Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity .

HY-P3143

BMSpep-57	PD-1/PD-L1	Cancer
BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC₅₀ of 7.68 nM. BMSpep-57 binds to PD-L1 with K_ds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .

HY-P3143A

BMSpep-57 hydrochloride	PD-1/PD-L1	Cancer
BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC₅₀ of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with K_ds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .

HY-P10271

RG7697	GLP Receptor	Metabolic Disease
RG7697 is a dual agonist for glucagon-like peptide receptor (GLP Receptor) and glucosedependent insulinotropic polypeptide receptor (GIPR), with EC₅₀ of 5 and 3 pM, respectively. RG7697 exhibits antihyperglycemic property .

HY-113560

Plipastatin B1	Antibiotic Fungal Phospholipase	Infection
Plipastatin B1 is a lipopeptide antibiotic, an inhibitor of phospholipase A₂ (PLA2), which has antifungal activity .

HY-P1162

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin SKF 100273	Vasopressin Receptor	Metabolic Disease
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist .

HY-P4146

Survodutide BI 456906	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P4146A

Survodutide TFA BI 456906 TFA	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P2595

SKF 103784	Peptides	Cardiovascular Disease
SKF 103784 is an vasopressin antagonist with activity against vasopressin. SKF 103784 inhibits the physiological response caused by antidiuretic and is therefore used to study biological processes related to water and salt balance. SKF 103784 can also be used to explore pathological mechanisms related to cardiovascular diseases and endocrine dysfunction .

HY-P4895

(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin	Oxytocin Receptor	Neurological Disease
(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. (d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin can be used for the research of neurological disease .

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

HY-P10881

Ganipatide	Peptide-Drug Conjugates (PDCs)	Metabolic Disease
Ganipatide is a 1-31-Glucose-dependent insulinotropic polypeptide. Ganipatide is promising for research of diabetes .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-105055

Didemnin B	Peptides	Cancer
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .

HY-P5524

C12-iE-DAP Lauroyl-γ-D-glutamyl-meso-Diaminopimelic acid; γ-D-glutamyl-meso-Diaminopimelic acid	NOD-like Receptor (NLR)	Others
C12-iE-DAP (Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid) is a biological active peptide. (a lauroyl (C12) group to the glutamic residue of iE-DAP , NOD1 agonist)

HY-P10579

123B9	Ephrin Receptor	Cancer
123B9, a tumor-homing agent, is a potent and selective EphA2 agonist with a K_d value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. 123B9 does not appreciably inhibit the ligand binding domains of the most closely related EphA3 and EphA4 receptors .

HY-125586

β-Amanitin	DNA/RNA Synthesis ADC Cytotoxin	Cancer
β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .

HY-P4755

*N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide*	Peptides	Others
N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-158104

LPPM-8	ATF6	Others
LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .

HY-P3100

Orfamide A	Parasite	Infection
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC₅₀ value of 34.5 μg/mL .

HY-P2075

EMD 55068	Renin	Endocrinology
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .

HY-P2336A

CCZ01048 TFA 2 Publications Verification	Melanocortin Receptor	Cancer
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-W037451

Methyl L-leucinate	Amino Acid Derivatives	Others
Methyl L-leucinate, methyl ester of L-leucine, is an alpha-amino acid ester. Methyl L-leucinate is a derivative of methyl ester and L-leucine, a class of compounds containing both amino and carboxyl groups in the molecule .

HY-117141

*N-Arachidonoyl-3-hydroxy-γ-aminobutyric acid* AGABA	Amino Acid Derivatives	Others
N-Arachidonoyl-3-hydroxy-γ-aminobutyric acid is an arachidonoyl amino acid .

HY-34611

Boc-L-2,4-Diaminobutyric acid N-Boc-L-2,4-Diaminobutyric acid; Boc-Dab-OH	Drug Derivative	Neurological Disease Cancer
Boc-L-2,4-Diaminobutyric acid is a derivative of L-2,4-Diaminobutyric acid (HY-101414) ^[1.

HY-W015424

N-Methyl-DL-glutamic acid 1 Publications Verification	Endogenous Metabolite	Others
N-Methyl-DL-glutamic acid is a L-Glutamic acid (HY-14608) analog with cytotoxic effects .

HY-41631

Boc-Pyr-Oet (S)-Ethyl-N-Boc-pyroglutamate	Amino Acid Derivatives	Others
Boc-Pyr-Oet is a derivative of L-Pyroglutamic acid (HY-76082). Boc-Pyr-Oet can be used for the synthesis of agents or other compounds .

HY-W145762

Fmoc-N-Me-D-Arg(Pbf)-OH	Amino Acid Derivatives	Others
Fmoc-N-Me-D-Arg(Pbf)-OH is an amino acid derivative .

HY-W291634

H-D-Glu-OtBu hydrochloride	Amino Acid Derivatives	Others
H-D-Glu-OtBu (hydrochloride) is a glutamic acid derivative .

HY-W016012

Glu-Glu	Amino Acid Derivatives	Others
Glu-Glu is a glutamic acid derivative containing amino and carboxyl groups. Glu-Glu is an analogs of acidic tripeptide and can contribute to calcium absorption .

HY-W016330

H-His(1-Me)-OMe	Amino Acid Derivatives	Others
H-His(1-Me)-OMe is a histidine derivative that can be used for amino acid synthesis .

HY-30216AR

Leucic acid (Standard)	Endogenous Metabolite	Others
Leucic acid (Standard) is the analytical standard of Leucic acid. This product is intended for research and analytical applications. Leucic acid is an amino acid metabolite .

HY-30216A

Leucic acid α-Hydroxyisocaproic acid	Endogenous Metabolite	Others
Leucic acid is an amino acid metabolite .

Cat. No.	Product Name		Classification

HY-151508

Diamino lipid DAL4		Cationic Lipids
Diamino lipid DAL4 is diamino lipid for the preparation of lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12, IL-27 and GM-CSF. Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity .

HY-154046

*4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine*		Nucleosides and their Analogs
4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152773

*2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine*		Nucleosides and their Analogs
2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

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1,3-Diamino-2-hydroxypropane-N,N,N′,N′-tetraacetic acid

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