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beta-Carotene

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (4) Bcl-2 Family (1) Biochemical Assay Reagents (1) Caspase (1) Cholinesterase (ChE) (1) COX (1) Drug Derivative (1) Drug Metabolite (2) Endogenous Metabolite (6) IAP (1) Isotope-Labeled Compounds (4) Nucleoside Antimetabolite/Analog (1) Organoid (1) Reactive Oxygen Species (ROS) (3) Reference Standards (1) TNF Receptor (1)
By Research Areas:	Cancer (5) Inflammation/Immunology (2) Metabolic Disease (3)
Click Chemistry:	Azide (1)

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Targets Recommended: Amyloid-β TGF-β Receptor Beta-secretase β-glucuronidase 3β-HSD TGF-beta/Smad 17β-HSD β-catenin 11β-HSD Beta-lactamase Dopamine β-hydroxylase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0411

*β-Carotene* 2 Publications Verification Provitamin A; beta-Carotene	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)	Metabolic Disease Cancer
β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-N0411R

β-Carotene (Standard) Provitamin A (Standard); beta-Carotene (Standard)	Reference Standards Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)	Metabolic Disease Cancer
β-Carotene (Standard) is the analytical standard of β-Carotene. This product is intended for research and analytical applications. β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-N0411S1

β-Carotene-d8 Provitamin A-d₈; beta-Carotene-d₈	Isotope-Labeled Compounds	Others
β-Carotene-d₈ is the deuterium labeled β-Carotene (HY-N0411) .

HY-N0411S4

β-Carotene-13C10 Provitamin A-_{13_{C_{10_{; beta-Carotene-_{13_C₁₀}}}}}	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)	Metabolic Disease Cancer
β-Carotene- ¹³C₁₀ (Provitamin A- ¹³C₁₀) is the ¹³C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-136234

9-cis-β-Carotene 9Z β-Carotene	Endogenous Metabolite	Others
9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. 9-cis-β-Carotene inhibits photoreceptor degeneration and restores retinal function in vivo. 9-cis-β-Carotene has the potential for the study of congenital stationary night blindness and fundus albipunctatus .

HY-W750682

β-Carotene 5,6-epoxide	Drug Derivative	Others
β-Carotene 5,6-epoxide, a carotenoid, is a degradation product of β-carotene. β-Carotene 5,6-epoxide can be found in isolated chloroplasts. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-N15378

β-Carotene-15,15'-epoxide	IAP Bcl-2 Family COX TNF Receptor Caspase Apoptosis	Inflammation/Immunology Cancer
β-carotene-15,15ʹ-epoxide is a XIAP antagonist with apoptosis-inducing and antitumor activity, found in the leaves of Spondias mombin. In a DMBA (HY-W011845)-induced rat model of breast cancer, β-carotene-15,15ʹ-epoxide binds to the BIR3 domain of the anti-apoptotic protein XIAP, blocking its interaction with caspase-9 and thereby promoting tumor cell apoptosis. In addition, β-carotene-15,15ʹ-epoxide significantly downregulates the expression of BCL-2, COX-2, and TNF-α in tumor tissues, reduces MDA levels, increases catalase activity, and modulates serum levels of LDH, ALP, and ALT, demonstrating strong antioxidant, anti-inflammatory, and metabolic protective effects. β-carotene-15,15ʹ-epoxide may be used in research on inflammation-related conditions and cancers such as breast cancer .

HY-133183

Urolignoside	Biochemical Assay Reagents	Others
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model .

HY-N15681

β-Apo-10'-carotenal 10'-Apo-β-carotenal	Drug Metabolite	Others
β-Apo-10'-carotenal is a degradation product of β,β-carotene. β-Apo-10'-carotenal can be used in flavor research .

HY-W750707

4-Hydroxyechinenone	Drug Metabolite	Others
4-Hydroxyechinenone is a trace carotenoid present in the carapaces of crabs. 4-Hydroxyechinenone is also an intermediate in the metabolism of β-Carotene (HY-N0411) to Astaxanthin (HY-B2163) .

HY-W009310

9-cis-Retinal	Endogenous Metabolite Organoid	Others
9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II with K_ds of 8 nM and 5 nM, respectively. 9-cis-Retinal expedites differentiation and maturation of rod photoreceptors in retinal organoids .

HY-W700062

β-Cyclocitral-d5	Isotope-Labeled Compounds	Others
β-Cyclocitral-d₅ is the deuterium labeled β-Cyclocitral (HY-W010231). β-Cyclocitral, a volatile oxidized derivative of β-carotene, is a grazer defence signal unique to the Cyanobacterium Microcystis. β-Cyclocitral, one of the predominant volatile terpenoid compounds, can upregulate the expression of defence genes to enhance excess light (EL) acclimation. β-Cyclocitral is a powerful repellent .

HY-131803

3'-Azido-3'-deoxyguanosine	Nucleoside Antimetabolite/Analog	Inflammation/Immunology
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-P5189A

*His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA*	Endogenous Metabolite Cholinesterase (ChE)	Others
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .

HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2	Isotope-Labeled Compounds	Cancer
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

Cat. No.	Product Name	Target	Research Area

HY-P5189A

*His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA*	Endogenous Metabolite Cholinesterase (ChE)	Others
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .

HY-P4285

β-Aspartylalanine	Peptides	Others
β-Aspartylalanine is a substrate for β-aspartyl peptidase and used to measure β-aspartyl peptidase activity in fecal supernatants .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0411

*β-Carotene* 2 Publications Verification Provitamin A; beta-Carotene	Structural Classification Classification of Application Fields Source classification Endocrine diseases Metabolic Disease Plants Endogenous metabolite Food Research Other Terpenoids Immune System Disorder other families Terpenoids Disease markers Pigments Disease Research Fields Cancer	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)
β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-N0411R

β-Carotene (Standard) Provitamin A (Standard); beta-Carotene (Standard)	Other Terpenoids Structural Classification Immune System Disorder other families Terpenoids Source classification Disease markers Endocrine diseases Plants Endogenous metabolite Cancer	Reference Standards Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)
β-Carotene (Standard) is the analytical standard of β-Carotene. This product is intended for research and analytical applications. β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-W009310

9-cis-Retinal	Structural Classification Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Endogenous metabolite Disease Research Fields	Endogenous Metabolite Organoid
9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II with K_ds of 8 nM and 5 nM, respectively. 9-cis-Retinal expedites differentiation and maturation of rod photoreceptors in retinal organoids .

HY-W750682

β-Carotene 5,6-epoxide	Structural Classification Natural Products Microorganisms Source classification	Drug Derivative
β-Carotene 5,6-epoxide, a carotenoid, is a degradation product of β-carotene. β-Carotene 5,6-epoxide can be found in isolated chloroplasts. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-N15378

β-Carotene-15,15'-epoxide	Structural Classification Natural Products Source classification Spondias mombin L. Plants Anacardiaceae	IAP Bcl-2 Family COX TNF Receptor Caspase Apoptosis
β-carotene-15,15ʹ-epoxide is a XIAP antagonist with apoptosis-inducing and antitumor activity, found in the leaves of Spondias mombin. In a DMBA (HY-W011845)-induced rat model of breast cancer, β-carotene-15,15ʹ-epoxide binds to the BIR3 domain of the anti-apoptotic protein XIAP, blocking its interaction with caspase-9 and thereby promoting tumor cell apoptosis. In addition, β-carotene-15,15ʹ-epoxide significantly downregulates the expression of BCL-2, COX-2, and TNF-α in tumor tissues, reduces MDA levels, increases catalase activity, and modulates serum levels of LDH, ALP, and ALT, demonstrating strong antioxidant, anti-inflammatory, and metabolic protective effects. β-carotene-15,15ʹ-epoxide may be used in research on inflammation-related conditions and cancers such as breast cancer .

HY-133183

Urolignoside	Structural Classification Natural Products Source classification Cinnamomum verum J. Presl Plants Lauraceae	Biochemical Assay Reagents
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model .

HY-N15681

β-Apo-10'-carotenal 10'-Apo-β-carotenal	Structural Classification Natural Products Microorganisms Source classification	Drug Metabolite
β-Apo-10'-carotenal is a degradation product of β,β-carotene. β-Apo-10'-carotenal can be used in flavor research .

HY-W750707

4-Hydroxyechinenone	Structural Classification Natural Products Animals Source classification	Drug Metabolite
4-Hydroxyechinenone is a trace carotenoid present in the carapaces of crabs. 4-Hydroxyechinenone is also an intermediate in the metabolism of β-Carotene (HY-N0411) to Astaxanthin (HY-B2163) .

Cat. No.	Product Name	Chemical Structure

HY-N0411S1

β-Carotene-d8
β-Carotene-d₈ is the deuterium labeled β-Carotene (HY-N0411) .

HY-N0411S4

β-Carotene-13C10
β-Carotene- ¹³C₁₀ (Provitamin A- ¹³C₁₀) is the ¹³C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

β-Carotene-13C10

β-Carotene- ¹³C₁₀ (Provitamin A- ¹³C₁₀) is the ¹³C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-W700062

β-Cyclocitral-d5
β-Cyclocitral-d₅ is the deuterium labeled β-Cyclocitral (HY-W010231). β-Cyclocitral, a volatile oxidized derivative of β-carotene, is a grazer defence signal unique to the Cyanobacterium Microcystis. β-Cyclocitral, one of the predominant volatile terpenoid compounds, can upregulate the expression of defence genes to enhance excess light (EL) acclimation. β-Cyclocitral is a powerful repellent .

β-Cyclocitral-d5

β-Cyclocitral-d₅ is the deuterium labeled β-Cyclocitral (HY-W010231). β-Cyclocitral, a volatile oxidized derivative of β-carotene, is a grazer defence signal unique to the Cyanobacterium Microcystis. β-Cyclocitral, one of the predominant volatile terpenoid compounds, can upregulate the expression of defence genes to enhance excess light (EL) acclimation. β-Cyclocitral is a powerful repellent .

HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

Cat. No.	Product Name		Classification

HY-131803

3'-Azido-3'-deoxyguanosine		Azide
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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beta-Carotene

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Isotope-Labeled Compounds

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