Search Result
Results for "
PEPS
" in MedChemExpress (MCE) Product Catalog:
4
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-137220
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-
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- HY-P5366
-
|
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Liposome
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Others
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PEP1 is a biological active peptide. (PEP1 binds to POPC SLBs at Low Concentration, High Concentration of PEP1 Leads to POPC SLBs Lysis)
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- HY-RS17812
-
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Lap; Pep7; PEPS; LAP-3; Lapep; Pep-7; Pep-S; 2410015L10Rik
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Small Interfering RNA (siRNA)
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Others
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Lap3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lap3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Lap3 Mouse Pre-designed siRNA Set A
Lap3 Mouse Pre-designed siRNA Set A
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- HY-RS07520
-
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LAP; PEPS; LAPEP; HEL-S-106
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Small Interfering RNA (siRNA)
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Others
|
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LAP3 Human Pre-designed siRNA Set A contains three designed siRNAs for LAP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
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LAP3 Human Pre-designed siRNA Set A
LAP3 Human Pre-designed siRNA Set A
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- HY-125432
-
-
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- HY-P10870
-
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Peptide-Drug Conjugates (PDCs)
FGFR
Apoptosis
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Cancer
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Pep1-DNP conjugate 9 is a functionalized peptide which is composed of the DNP-Hapten and the FGFR1 binding peptide. Pep1-DNP conjugate 9 exhibits good affinity to FGFR1 with KD of 5.01 μM. Pep1-DNP conjugate 9 recruits anti-DNP antibodies to the surface of FGFR1-positive cells, inhibits the FGF2-induced proliferation in rat skeletal myoblast cells, and induces apoptosis. Pep1-DNP conjugate 9 exhibits antitumor efficacy in mouse models .
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- HY-P10949
-
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Glycoprotein VI
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Cardiovascular Disease
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Pep-10L peptide is a glycoprotein VI (GPVI) antagonist with Ki values of 180, 225, and 179 μM for CPR, GPO-1, and Type 1 collagen, respectively. Pep-10L peptide has anti-thrombotic effects .
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- HY-172273B
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Liposome
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Cancer
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DSPE-PEG5000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-M2pep can be used for drug delivery .
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- HY-172273A
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Liposome
|
Cancer
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DSPE-PEG2000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-M2pep can be used for drug delivery .
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- HY-172273
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Liposome
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Cancer
|
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DSPE-PEG1000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-M2pep can be used for drug delivery .
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- HY-172273C
-
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Liposome
|
Cancer
|
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DSPE-PEG3400-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-M2pep can be used for drug delivery .
|
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-
- HY-P3496
-
|
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Pyroptosis
|
Inflammation/Immunology
|
|
Pep19-2.5 is an synthetic and antitoxin peptide, blocks the intracellular endotoxin signaling cascade. Pep19-2.5 inhibits signaling of lipopeptides (LP) and lipopolysaccharides (LPS) mediated by transmembrane and cytosolic pattern recognition receptors (PRRs). The signaling cascades lead to inflammation and cell pyroptosis .
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- HY-P10630
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Amyloid-β
|
Neurological Disease
|
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Pep63 is a neuroprotective peptide (VFQVRARTVA). Pep63 has a neuroprotective effect on synaptic plasticity and memory. Pep63 can competitively bind with Aβ1-42 oligomers, and can block Aβ fiber formation. Pep63 can be used for Alzheimer’s disease (AD) research .
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- HY-P2276
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PCSK9
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Cancer
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Pep2-8 is a PCSK9 inhibitor with a binding KD of 0.7 μM and an IC50 of 1.4 μM .
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- HY-P2276A
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-
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- HY-P0184
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NO Synthase
|
Neurological Disease
|
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Camstatin, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase .
|
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- HY-P0184A
-
|
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NO Synthase
|
Neurological Disease
|
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Camstatin TFA, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase .
|
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- HY-P1054
-
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YNVYGIEEVKI
|
PKC
|
Neurological Disease
|
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pep2-EVKI (YNVYGIEEVKI) is an inhibitor peptide that selectively blocks PICK1 interactions, caused the opposite effects on synaptic AMPAR function to PICK1 expression .
|
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- HY-19123
-
-
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- HY-P10292
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-
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- HY-P1399
-
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Myr-Pep2m
|
PKC
|
Neurological Disease
|
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Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .
|
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- HY-P1399A
-
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Myr-Pep2m TFA
|
PKC
|
Neurological Disease
|
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Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .
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- HY-P4490
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- HY-113167
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DL-2-phosphoglyceric acid
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Endogenous Metabolite
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Metabolic Disease
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2-Phosphoglyceric acid (DL-2-phosphoglyceric acid) is a glycolysis substrate. It is catalyzed by enolase into phosphoenolpyruvate (PEP) .
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- HY-15114
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S 17092-1
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Prolyl Endopeptidase (PREP)
Apoptosis
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Neurological Disease
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S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC50 of 1.2 nM. S 17092 inhibits cell apoptosis. S 17092 mechanism of action is to inhibit the activity of PEP, slowing down the degradation of neuroactive peptides and thus enhancing memory function. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging .
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- HY-113951
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Boc-Pro-prolinal; (Boc)-Prolyl-prolinal
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Prolyl Endopeptidase (PREP)
|
Neurological Disease
|
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Prolyl Endopeptidase Inhibitor 1 (Boc-Pro-prolinal) is a potent prolyl endopeptidase (PEP; PE) inhibitor, with a Ki value of 15 nM. Prolyl Endopeptidase Inhibitor 1 has anti-amnesic effect .
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- HY-162452
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Prolyl Endopeptidase (PREP)
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Neurological Disease
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Prolyl endopeptidase inhibitor 2 (Compound 8) was a proline endopeptidase (PEP) inhibitor with IC50 value 31.11 μM. Prolyl endopeptidase inhibitor 2 can be used in the study of neurodegenerative diseases .
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- HY-E70435
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PEP-Mx
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Biochemical Assay Reagents
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Others
|
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Prolylendopeptidase, myxococcus xanthus (PEP-Mx) is an endopeptidase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .
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- HY-N15009
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Prolyl Endopeptidase (PREP)
|
Infection
|
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Kynapcin-13 can non-competitively inhibit the activity of prolyl endopeptidase (PEP) with an IC50 of 76.80 μM. Kynapcin-13 has a little inhibitory effect on other serine proteases .
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- HY-N15010
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Prolyl Endopeptidase (PREP)
|
Infection
|
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Kynapcin-28 can non-competitively inhibit the activity of prolyl endopeptidase (PEP) with an IC50 of 76.80 μM. Kynapcin-28 has a little inhibitory effect on other serine proteases .
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- HY-P99792
-
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NM57; rhRIG
|
RABV
|
Infection
|
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Ormutivimab (rhRIG) is a recombinant human monoclonal antibody, targeting rabies virus. Ormutivimab neutralizes a variety of rabies virus strains. Ormutivimab exhibits potent potency against rabies post-exposure prophylaxis (PEP) model .
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- HY-110124
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Pyruvate Kinase
|
Cancer
|
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ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), which can affect the cooperativity of phosphoenolpyruvate (PEP) binding, while adenosine diphosphate (ADP) binding almost no effect .
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- HY-148331
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|
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Prolyl Endopeptidase (PREP)
|
Neurological Disease
|
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Z-Thioprolyl-Thioproline is a bovine brain prolyl endopeptidase (PEP) inhibitor (IC50=16 µM; Ki=37 µM). Z-Thioprolyl-Thioproline is used in the study of neurological disorders such as memory disorders and cognitive disorders .
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- HY-106364
-
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Bleomycin PEP; Pepleomycin
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Antibiotic
|
Cancer
|
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Peplomycin (Bleomycin PEP; Pepleomycin) is an antibiotic analogue of Bleomycin (HY-108345), with high antitumor effect and less pulmonary toxicity. Peplomycin induce apoptosis in oral squamous carcinoma cell line SSCKN cells and pulmonary fibrosis in rats .
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- HY-141436
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Sucrose octasulfate potassium
|
Biochemical Assay Reagents
|
Cancer
|
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Sucrosofate (Sucrose octasulfate) potassium is a sucrose acid that can be used to prepare liposomes to deliver Irinotecan (HY-16562). Irinotecan is an inhibitor of topoisomerase Topo I and is commonly used in colon and rectal cancer research. Sucrosofate nanoliposome preparation loaded with Irinotecan, also known as PEP02 or MM-398 .
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- HY-W712327
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Biochemical Assay Reagents
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Others
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D-Xylulose 5-phosphate (sodium) is a pentose phosphate ester and an essential intermediate metabolite in the pentose phosphate pathway (PPP) and the non-oxidative phase of the pentose phosphate pathway. D-xylulose-5-phosphate can be efficiently synthesized through the phosphorylation of D-xylulose catalyzed by D-xylulokinase (XKS1 from Saccharomyces cerevisiae), with ATP regeneration facilitated by the phosphoenolpyruvate (PEP)/pyruvate kinase (PK) system .
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- HY-141436R
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Sucrose octasulfate potassium (Standard)
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Biochemical Assay Reagents
Reference Standards
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Cancer
|
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Sucrosofate (potassium) (Standard) is the analytical standard of Sucrosofate (potassium). This product is intended for research and analytical applications. Sucrosofate (Sucrose octasulfate) potassium is a sucrose acid that can be used to prepare liposomes to deliver Irinotecan (HY-16562). Irinotecan is an inhibitor of topoisomerase Topo I and is commonly used in colon and rectal cancer research. Sucrosofate nanoliposome preparation loaded with Irinotecan, also known as PEP02 or MM-398 .
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- HY-P2819A
-
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Endogenous Metabolite
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Metabolic Disease
|
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Phosphofructokinase from Bacillus stearothermophilus is a key enzyme in sugar metabolism that catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate during glycolysis. The enzyme's ability to bind fructose-6-phosphate can be inhibited by phosphoenolpyruvate (PEP), thereby regulating the rate of glycolysis. Phosphofructokinase from Bacillus stearothermophilus can be used for the measurement of fructose-6-phosphate levels .
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- HY-D1313
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|
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Fluorescent Dye
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Others
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PEP azide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
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| Cat. No. |
Product Name |
Type |
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- HY-D1313
-
|
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Fluorescent Dyes/Probes
|
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PEP azide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
| Cat. No. |
Product Name |
Type |
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- HY-172273B
-
|
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Drug Delivery
|
|
DSPE-PEG5000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-M2pep can be used for drug delivery .
|
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- HY-172273A
-
|
|
Drug Delivery
|
|
DSPE-PEG2000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-M2pep can be used for drug delivery .
|
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- HY-172273
-
|
|
Drug Delivery
|
|
DSPE-PEG1000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-M2pep can be used for drug delivery .
|
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- HY-172273C
-
|
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Drug Delivery
|
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DSPE-PEG3400-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-M2pep can be used for drug delivery .
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P1848
-
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- HY-P4119A
-
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Peptides
|
Others
|
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Pep-1-Cysteamine TFA is a chimeric cell-penetrating peptide (CPP) with a primary amphipathicity. Pep-1-Cysteamine TFA has the ability to translocate across biological membranes and introduce active proteins inside cells .
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- HY-P5366
-
|
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Liposome
|
Others
|
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PEP1 is a biological active peptide. (PEP1 binds to POPC SLBs at Low Concentration, High Concentration of PEP1 Leads to POPC SLBs Lysis)
|
-
- HY-P3496
-
|
|
Pyroptosis
|
Inflammation/Immunology
|
|
Pep19-2.5 is an synthetic and antitoxin peptide, blocks the intracellular endotoxin signaling cascade. Pep19-2.5 inhibits signaling of lipopeptides (LP) and lipopolysaccharides (LPS) mediated by transmembrane and cytosolic pattern recognition receptors (PRRs). The signaling cascades lead to inflammation and cell pyroptosis .
|
-
- HY-P2276
-
|
|
PCSK9
|
Cancer
|
Pep2-8 is a PCSK9 inhibitor with a binding KD of 0.7 μM and an IC50 of 1.4 μM .
|
-
- HY-125432
-
-
- HY-P4119
-
|
|
Peptides
|
Others
|
|
Pep-1-Cysteamine is a chimeric cell-penetrating peptide (CPP) with a primary amphipathicity. Pep-1-Cysteamine has the ability to translocate across biological membranes and introduce active proteins inside cells .
|
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- HY-P10870
-
|
|
Peptide-Drug Conjugates (PDCs)
FGFR
Apoptosis
|
Cancer
|
|
Pep1-DNP conjugate 9 is a functionalized peptide which is composed of the DNP-Hapten and the FGFR1 binding peptide. Pep1-DNP conjugate 9 exhibits good affinity to FGFR1 with KD of 5.01 μM. Pep1-DNP conjugate 9 recruits anti-DNP antibodies to the surface of FGFR1-positive cells, inhibits the FGF2-induced proliferation in rat skeletal myoblast cells, and induces apoptosis. Pep1-DNP conjugate 9 exhibits antitumor efficacy in mouse models .
|
-
- HY-P10949
-
|
|
Glycoprotein VI
|
Cardiovascular Disease
|
|
Pep-10L peptide is a glycoprotein VI (GPVI) antagonist with Ki values of 180, 225, and 179 μM for CPR, GPO-1, and Type 1 collagen, respectively. Pep-10L peptide has anti-thrombotic effects .
|
-
- HY-P10630
-
|
|
Amyloid-β
|
Neurological Disease
|
|
Pep63 is a neuroprotective peptide (VFQVRARTVA). Pep63 has a neuroprotective effect on synaptic plasticity and memory. Pep63 can competitively bind with Aβ1-42 oligomers, and can block Aβ fiber formation. Pep63 can be used for Alzheimer’s disease (AD) research .
|
-
- HY-P2276A
-
-
- HY-P0184
-
|
|
NO Synthase
|
Neurological Disease
|
|
Camstatin, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase .
|
-
- HY-P0184A
-
|
|
NO Synthase
|
Neurological Disease
|
|
Camstatin TFA, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase .
|
-
- HY-P1054
-
|
YNVYGIEEVKI
|
PKC
|
Neurological Disease
|
|
pep2-EVKI (YNVYGIEEVKI) is an inhibitor peptide that selectively blocks PICK1 interactions, caused the opposite effects on synaptic AMPAR function to PICK1 expression .
|
-
- HY-113871
-
-
- HY-P10292
-
-
- HY-P1399
-
|
Myr-Pep2m
|
PKC
|
Neurological Disease
|
|
Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .
|
-
- HY-P1399A
-
|
Myr-Pep2m TFA
|
PKC
|
Neurological Disease
|
|
Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .
|
-
- HY-P4490
-
-
- HY-P10374
-
|
|
Peptides
|
Cancer
|
|
Pep42, a cyclic peptide ligand of GPR78, internalizes selectively into highly metastatic human melanoma cells through a receptor-mediated process .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P99792
-
|
NM57; rhRIG
|
RABV
|
Infection
|
|
Ormutivimab (rhRIG) is a recombinant human monoclonal antibody, targeting rabies virus. Ormutivimab neutralizes a variety of rabies virus strains. Ormutivimab exhibits potent potency against rabies post-exposure prophylaxis (PEP) model .
|
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Product Name |
Category |
Target |
Chemical Structure |
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* This product has been "discontinued".
Optimized version of product available:
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| Cat. No. |
Product Name |
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Classification |
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- HY-D1313
-
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Azide
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PEP azide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-RS17812
-
|
Lap; Pep7; PEPS; LAP-3; Lapep; Pep-7; Pep-S; 2410015L10Rik
|
|
siRNAs
Mouse Pre-designed siRNA Sets
|
|
Lap3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lap3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
- HY-RS07520
-
|
LAP; PEPS; LAPEP; HEL-S-106
|
|
siRNAs
Human Pre-designed siRNA Sets
|
|
LAP3 Human Pre-designed siRNA Set A contains three designed siRNAs for LAP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
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