Search Result
Results for "
γ-lactone
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
2
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W050049
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Biochemical Assay Reagents
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Others
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2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate is a chemically synthesized fluorinated carbohydrate derivative that can be used in glycobiology research .
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- HY-W053519
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Drug Intermediate
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Infection
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DL-Pantolactone is a γ-lactone that can be hydrolyzed to Pantoic acid (HY-W399035) by the lactonohydrolase of Fusarium oxysporum. DL-Pantolactone also can be used in the preparation of 3,5-dinitrobenzoyl-DL-pantolactone .
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- HY-150980S
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Isotope-Labeled Compounds
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Others
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1,2-O-Isopropylidene-β-L-idofuranuronic-6- 13C acid γ-lactone is the 13C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid γ-lactone .
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- HY-150981S
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Isotope-Labeled Compounds
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Others
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1,2-O-Isopropylidene-a-D-glucofuranuronic-6- 13C acid, γ-lactone is the 13C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid, γ-lactone .
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- HY-W077275
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Biochemical Assay Reagents
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Others
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5,6-Isopropylidene-L-gulonic acid γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-41357
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Biochemical Assay Reagents
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Others
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2,3-O-(1-Methylethylidene)-L-lyxonic acid γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-N1108
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Others
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Others
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Uvedalin is a conjugated γ-lactone and oxygenated germacranolide that can be isolated from Polymnia uvedalia (L.) .
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- HY-N13911
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- HY-W416216
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- HY-W705252
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Biochemical Assay Reagents
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Others
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D-Talonic acid,γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W795499
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Biochemical Assay Reagents
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Others
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D-Erythro-L-talo-octonic acid,γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W698427
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Biochemical Assay Reagents
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Others
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D-Mannonic acid,2-(acetylamino)-2-deoxy,γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W698426
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Biochemical Assay Reagents
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Others
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D-Galactonic acid,2-(acetylamino)-2-deoxy,γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-I0596
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Biochemical Assay Reagents
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Others
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D-Ribonic acid,2-C-methyl,γ-lactone,2,3,5-tribenzoate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W053519R
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Drug Intermediate
Reference Standards
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Infection
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DL-Pantolactone (Standard) is the analytical standard of DL-Pantolactone (HY-W053519). This product is intended for research and analytical applications. DL-Pantolactone is a γ-lactone that can be hydrolyzed to Pantoic acid (HY-W399035) by the lactonohydrolase of Fusarium oxysporum. DL-Pantolactone also can be used in the preparation of 3,5-dinitrobenzoyl-DL-pantolactone.
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- HY-W015892
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γ-Caprolactone
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Endogenous Metabolite
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Others
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γ-Hexalactone is a gamma-lactone found in ripe fruits. γ-Hexalactone induces DNA damage and acts a substrate of paraoxonase 1 (PON1) .
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- HY-N10272
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Fungal
Bacterial
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Infection
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Avenaciolide is an antifungal bis-γ-lactone found in Aspergillus avenaceus. Avenaciolide has also antibacterial action. Avenaciolide is a specific inhibitor of glutamate transport in rat liver mitochondria. Avenaciolide interferes with the ability of ADP to stimulate the rate of glutamate oxidation .
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- HY-W015892R
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Endogenous Metabolite
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Others
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γ-Hexalactone (Standard) is the analytical standard of γ-Hexalactone. This product is intended for research and analytical applications. γ-Hexalactone is a gamma-lactone found in ripe fruits. γ-Hexalactone induces DNA damage and acts a substrate of paraoxonase 1 (PON1) .
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- HY-41982
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D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone
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Endogenous Metabolite
Drug Derivative
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Cardiovascular Disease
Metabolic Disease
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D-Glucuronic acid lactone (D-Glucurono-6,3-lactone) is an endogenous metabolite, which is a glucuronic acid derivative. D-Glucuronic acid lactone can be used as starting regents in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, requirement for the preparation of 1-O-acyl glucuronide of the anti-inflammatory agent ML-3000 (HY-B1452), synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides. D-Glucuronic acid lactone is promising for research of reversible cerebral vasoconstriction syndrome (RCVS) .
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- HY-P2223
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Antibiotic
Bacterial
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Infection
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Hypeptin is a cyclo-deposited peptide antibiotic produced by Lysobacter sp.K5869. Hypeptin blocks bacterial cell wall biosynthesis by binding to multiple undecaprenyl pyrophosphate-containing biosynthesis intermediates，forming a stoichiometric 2:1 complex. Hypeptin has antibacterial activity .
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- HY-P2101
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- HY-P1709
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Bacterial
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Infection
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Protactin is a pentapeptide lactone produced by Streptomyces cucumeris strain L703-4 (ATCC 53784) with significant antioxidant properties. Protactin can be converted to actinomycin Zp by ferrocyanide oxidation. Actinomycin Zp exhibits potent antibacterial activity in vitro and has significant antitumor effects against P-388 leukemia in a mouse model .
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- HY-136410
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Endogenous Metabolite
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Metabolic Disease
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4-hydroxy Nonenal Mercapturic Acid (4-HNE) is generated by the peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid. 4-hydroxy Nonenal Mercapturic Acid is rapidly cleared from plasma and enters the enterohepatic circulation in rats as a glutathione conjugate. Approximately two-thirds of 4-hydroxy Nonenal Mercapturic Acid is excreted in the urine within 48 hours, primarily as mercapturic acid conjugates. Approximately half of the metabolites are C-1 aldehydes of 4-hydroxy Nonenal Mercapturic Acid that are reduced to alcohols. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form gamma-lactols and gamma-lactones, respectively, resulting in at least four or five final urinary metabolites of 4-HNE in vivo.
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- HY-P3990
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VEGFR
Autophagy
Apoptosis
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Cancer
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Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, shows potent antiproliferative activity. Coibamide A induces autophagosome accumulation via an mTOR-independent mechanism. Coibamide A induces apoptosis. Coibamide A inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts .
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- HY-P1720
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Antibiotic
Bacterial
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Infection
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Telomycin is a calcium-dependent antibiotic, which can be produced by Streptomyces. Telomycin inhibits gram-positive bacteria, including multidrug-resistant (MDR) pathogens .
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| Cat. No. |
Product Name |
Type |
-
- HY-W050049
-
|
|
Carbohydrates
|
|
2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-Lactone 3,5-dibenzoate is a chemically synthesized fluorinated carbohydrate derivative that can be used in glycobiology research .
|
-
- HY-W077275
-
|
|
Carbohydrates
|
|
5,6-Isopropylidene-L-gulonic acid γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-41357
-
|
|
Carbohydrates
|
|
2,3-O-(1-Methylethylidene)-L-lyxonic acid γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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- HY-W416216
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Carbohydrates
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D-Gulonic acid,γ-lactone,2,3,5,6-tetraacetate is a biochemical assay reagent.
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- HY-W705252
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Carbohydrates
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D-Talonic acid,γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W795499
-
|
|
Carbohydrates
|
|
D-Erythro-L-talo-octonic acid,γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W698427
-
|
|
Carbohydrates
|
|
D-Mannonic acid,2-(acetylamino)-2-deoxy,γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W698426
-
|
|
Carbohydrates
|
|
D-Galactonic acid,2-(acetylamino)-2-deoxy,γ-lactone is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-I0596
-
|
|
Carbohydrates
|
|
D-Ribonic acid,2-C-methyl,γ-lactone,2,3,5-tribenzoate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-N10272
-
|
|
Microbial Culture
|
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Avenaciolide is an antifungal bis-γ-lactone found in Aspergillus avenaceus. Avenaciolide has also antibacterial action. Avenaciolide is a specific inhibitor of glutamate transport in rat liver mitochondria. Avenaciolide interferes with the ability of ADP to stimulate the rate of glutamate oxidation .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P2223
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Hypeptin is a cyclo-deposited peptide antibiotic produced by Lysobacter sp.K5869. Hypeptin blocks bacterial cell wall biosynthesis by binding to multiple undecaprenyl pyrophosphate-containing biosynthesis intermediates，forming a stoichiometric 2:1 complex. Hypeptin has antibacterial activity .
|
-
- HY-P2101
-
-
- HY-P1709
-
|
|
Bacterial
|
Infection
|
|
Protactin is a pentapeptide lactone produced by Streptomyces cucumeris strain L703-4 (ATCC 53784) with significant antioxidant properties. Protactin can be converted to actinomycin Zp by ferrocyanide oxidation. Actinomycin Zp exhibits potent antibacterial activity in vitro and has significant antitumor effects against P-388 leukemia in a mouse model .
|
-
- HY-P3990
-
|
|
VEGFR
Autophagy
Apoptosis
|
Cancer
|
|
Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, shows potent antiproliferative activity. Coibamide A induces autophagosome accumulation via an mTOR-independent mechanism. Coibamide A induces apoptosis. Coibamide A inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts .
|
-
- HY-P1720
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Telomycin is a calcium-dependent antibiotic, which can be produced by Streptomyces. Telomycin inhibits gram-positive bacteria, including multidrug-resistant (MDR) pathogens .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W053519
-
-
-
- HY-W015892
-
-
-
- HY-41982
-
|
D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone
|
Structural Classification
Microorganisms
Classification of Application Fields
Ketones, Aldehydes, Acids
Source classification
Metabolic Disease
Endogenous metabolite
Disease Research Fields
|
Endogenous Metabolite
Drug Derivative
|
|
D-Glucuronic acid lactone (D-Glucurono-6,3-lactone) is an endogenous metabolite, which is a glucuronic acid derivative. D-Glucuronic acid lactone can be used as starting regents in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, requirement for the preparation of 1-O-acyl glucuronide of the anti-inflammatory agent ML-3000 (HY-B1452), synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides. D-Glucuronic acid lactone is promising for research of reversible cerebral vasoconstriction syndrome (RCVS) .
|
-
-
- HY-N1108
-
-
-
- HY-N13911
-
-
-
- HY-W053519R
-
-
-
- HY-N10272
-
-
-
- HY-W015892R
-
-
-
- HY-P1709
-
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-150980S
-
|
|
|
1,2-O-Isopropylidene-β-L-idofuranuronic-6- 13C acid γ-lactone is the 13C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid γ-lactone .
|
-
-
- HY-150981S
-
|
|
|
1,2-O-Isopropylidene-a-D-glucofuranuronic-6- 13C acid, γ-lactone is the 13C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid, γ-lactone .
|
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